chloroquine has been researched along with Granulocytic Leukemia, Chronic in 9 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| He, W | 1 |
| Zhao, CF | 1 |
| Chen, L | 1 |
| Hu, HX | 1 |
| Chiou, JT | 1 |
| Lee, YC | 1 |
| Chang, LS | 1 |
| Hseu, YC | 1 |
| Shen, YC | 1 |
| Kao, MC | 1 |
| Mathew, DC | 1 |
| Karuppaiya, P | 1 |
| Li, ML | 1 |
| Yang, HL | 1 |
| Kamitsuji, Y | 1 |
| Kuroda, J | 1 |
| Kimura, S | 1 |
| Toyokuni, S | 1 |
| Watanabe, K | 1 |
| Ashihara, E | 1 |
| Tanaka, H | 1 |
| Yui, Y | 1 |
| Watanabe, M | 1 |
| Matsubara, H | 1 |
| Mizushima, Y | 1 |
| Hiraumi, Y | 1 |
| Kawata, E | 1 |
| Yoshikawa, T | 1 |
| Maekawa, T | 1 |
| Nakahata, T | 1 |
| Adachi, S | 1 |
| Bellodi, C | 1 |
| Lidonnici, MR | 1 |
| Hamilton, A | 1 |
| Helgason, GV | 1 |
| Soliera, AR | 1 |
| Ronchetti, M | 1 |
| Galavotti, S | 1 |
| Young, KW | 1 |
| Selmi, T | 1 |
| Yacobi, R | 1 |
| Van Etten, RA | 1 |
| Donato, N | 1 |
| Hunter, A | 1 |
| Dinsdale, D | 1 |
| Tirrò, E | 1 |
| Vigneri, P | 1 |
| Nicotera, P | 1 |
| Dyer, MJ | 1 |
| Holyoake, T | 1 |
| Salomoni, P | 2 |
| Calabretta, B | 2 |
| Patel, H | 1 |
| Marley, SB | 1 |
| Gordon, MY | 1 |
| Carew, JS | 1 |
| Nawrocki, ST | 1 |
| Kahue, CN | 1 |
| Zhang, H | 1 |
| Yang, C | 1 |
| Chung, L | 1 |
| Houghton, JA | 1 |
| Huang, P | 1 |
| Giles, FJ | 1 |
| Cleveland, JL | 1 |
| Jiang, YZ | 1 |
| Mavroudis, D | 1 |
| Dermime, S | 1 |
| Hensel, N | 1 |
| Couriel, D | 1 |
| Molldrem, J | 1 |
| Barrett, AJ | 1 |
1 review available for chloroquine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Suppression of autophagy by BCR/ABL.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Benzamides; Chloroquine; Drug Sy | 2012 |
8 other studies available for chloroquine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
[Chloroquine Enhances BIIB021-induced Apoptosis in Chronic Myeloid Leukemia Cells Bearing T315I Mutation].
Topics: Adenine; Animals; Apoptosis; Autophagy; Caspase 3; Cell Line, Tumor; Chloroquine; Fusion Proteins, b | 2022 |
Hydroquinone-selected chronic myelogenous leukemia cells are sensitive to chloroquine-induced cytotoxicity via MCL1 suppression and glycolysis inhibition.
Topics: Apoptosis; Chloroquine; Glycolysis; Humans; Hydroquinones; K562 Cells; Leukemia, Myelogenous, Chroni | 2023 |
Ganoderma tsugae induced ROS-independent apoptosis and cytoprotective autophagy in human chronic myeloid leukemia cells.
Topics: Adenine; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Sur | 2019 |
The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias.
Topics: Animals; Apoptosomes; Autophagy; Caspases; Cell Line, Tumor; Chloroquine; Cytoprotection; Disease Mo | 2008 |
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.
Topics: Animals; Antineoplastic Agents; Autophagy; Benzamides; Calcium; Cell Death; Cell Line, Tumor; Chloro | 2009 |
Detection in primary chronic myeloid leukaemia cells of p210BCR-ABL1 in complexes with adaptor proteins CBL, CRKL, and GRB2.
Topics: Adaptor Proteins, Signal Transducing; Caspases; Cell Line, Tumor; Chloroquine; Fusion Proteins, bcr- | 2006 |
Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance.
Topics: Antineoplastic Agents; Autophagy; Cathepsin D; Cell Line, Tumor; Chloroquine; Drug Resistance, Neopl | 2007 |
Alloreactive CD4+ T lymphocytes can exert cytotoxicity to chronic myeloid leukaemia cells processing and presenting exogenous antigen.
Topics: Bone Marrow Transplantation; Brefeldin A; CD4-Positive T-Lymphocytes; Chloroquine; Cyclopentanes; Cy | 1996 |