chloroquine has been researched along with Glioma in 38 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The autophagy inhibitor chloroquine (CQ) potentiates temozolomide (TMZ) cytotoxicity in glioma cells, but it is not known whether CQ does this by inhibiting mitochondrial autophagy." | 7.81 | Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells. ( Akiyama, Y; Hori, YS; Horio, Y; Hosoda, R; Kuno, A; Maruyama, M; Mikami, T; Mikuni, N; Sebori, R; Sugino, T; Suzuki, K; Tsukamoto, M; Wanibuchi, M, 2015) |
| "Chloroquine has been shown to increase the cellular retention and nuclear incorporation of 125I-labeled monoclonal antibody (MAb) 425, a murine anti-epidermal growth factor receptor monoclonal antibody, in human high-grade glioma cells in vitro." | 7.69 | Biodistribution of 125I-MAb 425 in a human glioma xenograft model: effect of chloroquine. ( Bender, H; Brady, LW; Class, R; Dilling, TJ; Emrich, JG; Hand, CM, 1997) |
| "Targeting of toxic substances to the epidermal growth factor, EGF, receptor might be an attractive therapeutic approach because of the increased receptor-expression in some human tumours such as, for example, malignant gliomas and squamous lung carcinomas." | 7.68 | Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGF: studies on cultured glioma cells. ( Capala, J; Carlsson, J, 1991) |
| "Tritium-labeled neoglycolipids consisting of the oligosaccharide of ganglioside GM1 attached to cholesterol (GM1OSNH-X-CHOL), phosphatidylethanolamine (GM1OS-PE) and stearylamine (GM1OSNHC18) were synthesized and their uptake and metabolism by GM1-deficient rat glioma C6 cells were determined." | 7.68 | Metabolism of cholesterol, phosphatidylethanolamine and stearylamine analogues of GM1 ganglioside by rat glioma C6 cells. ( Fishman, PH; Pacuszka, T, 1991) |
| "Magnolol, a neolignan, has been known for its apoptotic role in glioma." | 5.91 | Magnolol induces cytotoxic autophagy in glioma by inhibiting PI3K/AKT/mTOR signaling. ( Das, CK; Das, S; Dhara, D; Kulkarni, G; Kundu, M; Mandal, M, 2023) |
| "Baicalein (BAI) is a natural flavonoid." | 5.51 | Baicalein Induces Autophagy and Apoptosis through AMPK Pathway in Human Glioma Cells. ( Ding, L; Li, L; Liu, B; Wang, B; Wang, S; Wang, Y; Zhang, L, 2019) |
| "Glioblastoma is the most common and aggressive primary brain tumor in adults." | 5.48 | Nitazoxanide, an antiprotozoal drug, inhibits late-stage autophagy and promotes ING1-induced cell cycle arrest in glioblastoma. ( Chen, X; Han, D; Hou, X; Liu, H; Liu, Z; Ma, J; Peng, F; Shen, C; Shu, M; Wang, K; Wang, L; Wang, X; Wu, J; Yang, G; Yin, Z; Zhang, D; Zhao, B; Zhao, S; Zhao, W; Zheng, Z; Zhong, C, 2018) |
| "Malignant glioma is the most aggressive brain tumor." | 5.46 | Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway. ( Chen, JT; Chen, RM; Cheng, BC; Chio, CC; Liu, SH; Yang, ST, 2017) |
| "Quercetin can inhibit cell viability and induce autophagy of U87 and U251 glioma cells in a dose-dependent manner." | 5.43 | Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells. ( Bi, Y; Gao, D; Hou, X; Li, C; Liu, H; Liu, Y; Liu, Z; Peng, F; Shen, C; Shi, C; Wang, K; Wang, X; Wu, J; Zhang, J; Zhao, B; Zhao, S; Zheng, Z; Zhong, C; Zou, H, 2016) |
| " The autophagy inhibitor chloroquine (CQ) potentiates temozolomide (TMZ) cytotoxicity in glioma cells, but it is not known whether CQ does this by inhibiting mitochondrial autophagy." | 3.81 | Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells. ( Akiyama, Y; Hori, YS; Horio, Y; Hosoda, R; Kuno, A; Maruyama, M; Mikami, T; Mikuni, N; Sebori, R; Sugino, T; Suzuki, K; Tsukamoto, M; Wanibuchi, M, 2015) |
| "These data suggest that the anti-proliferative activity of ADS-I in human glioma cells is associated with the activation of autophagy in addition to cell cycle arrest and apoptosis, and the antagonistic effect of chloroquine suggests an important role of autophagy in ADS-I-mediated cell death against tumor growth." | 3.80 | Stimulation of autophagic activity in human glioma cells by anti-proliferative ardipusilloside I isolated from Ardisia pusilla. ( Du, C; Guan, Q; Wang, L; Wang, PY; Wang, R; Wang, XJ; Xiao, X, 2014) |
| "Chloroquine has been shown to increase the cellular retention and nuclear incorporation of 125I-labeled monoclonal antibody (MAb) 425, a murine anti-epidermal growth factor receptor monoclonal antibody, in human high-grade glioma cells in vitro." | 3.69 | Biodistribution of 125I-MAb 425 in a human glioma xenograft model: effect of chloroquine. ( Bender, H; Brady, LW; Class, R; Dilling, TJ; Emrich, JG; Hand, CM, 1997) |
| "Targeting of toxic substances to the epidermal growth factor, EGF, receptor might be an attractive therapeutic approach because of the increased receptor-expression in some human tumours such as, for example, malignant gliomas and squamous lung carcinomas." | 3.68 | Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGF: studies on cultured glioma cells. ( Capala, J; Carlsson, J, 1991) |
| "Tritium-labeled neoglycolipids consisting of the oligosaccharide of ganglioside GM1 attached to cholesterol (GM1OSNH-X-CHOL), phosphatidylethanolamine (GM1OS-PE) and stearylamine (GM1OSNHC18) were synthesized and their uptake and metabolism by GM1-deficient rat glioma C6 cells were determined." | 3.68 | Metabolism of cholesterol, phosphatidylethanolamine and stearylamine analogues of GM1 ganglioside by rat glioma C6 cells. ( Fishman, PH; Pacuszka, T, 1991) |
| "Magnolol, a neolignan, has been known for its apoptotic role in glioma." | 1.91 | Magnolol induces cytotoxic autophagy in glioma by inhibiting PI3K/AKT/mTOR signaling. ( Das, CK; Das, S; Dhara, D; Kulkarni, G; Kundu, M; Mandal, M, 2023) |
| "Baicalein (BAI) is a natural flavonoid." | 1.51 | Baicalein Induces Autophagy and Apoptosis through AMPK Pathway in Human Glioma Cells. ( Ding, L; Li, L; Liu, B; Wang, B; Wang, S; Wang, Y; Zhang, L, 2019) |
| "Glioblastoma is the most common and aggressive primary brain tumor in adults." | 1.48 | Nitazoxanide, an antiprotozoal drug, inhibits late-stage autophagy and promotes ING1-induced cell cycle arrest in glioblastoma. ( Chen, X; Han, D; Hou, X; Liu, H; Liu, Z; Ma, J; Peng, F; Shen, C; Shu, M; Wang, K; Wang, L; Wang, X; Wu, J; Yang, G; Yin, Z; Zhang, D; Zhao, B; Zhao, S; Zhao, W; Zheng, Z; Zhong, C, 2018) |
| "Treatment with chloroquine, or knockdown of the autophagy gene ATG5, inhibited the formation of VM and KDR phosphorylation in GSCs." | 1.46 | Autophagy-induced KDR/VEGFR-2 activation promotes the formation of vasculogenic mimicry by glioma stem cells. ( Bian, XW; Chen, Q; Fu, WJ; Niu, Q; Ping, YF; Wang, JM; Weng, HY; Wu, HB; Yang, S; Yao, XH; Zhang, X; Zhao, XL, 2017) |
| "Malignant glioma is the most aggressive brain tumor." | 1.46 | Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway. ( Chen, JT; Chen, RM; Cheng, BC; Chio, CC; Liu, SH; Yang, ST, 2017) |
| "Quercetin can inhibit cell viability and induce autophagy of U87 and U251 glioma cells in a dose-dependent manner." | 1.43 | Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells. ( Bi, Y; Gao, D; Hou, X; Li, C; Liu, H; Liu, Y; Liu, Z; Peng, F; Shen, C; Shi, C; Wang, K; Wang, X; Wu, J; Zhang, J; Zhao, B; Zhao, S; Zheng, Z; Zhong, C; Zou, H, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (10.53) | 18.7374 |
| 1990's | 7 (18.42) | 18.2507 |
| 2000's | 4 (10.53) | 29.6817 |
| 2010's | 19 (50.00) | 24.3611 |
| 2020's | 4 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Jing, Y | 1 |
| Kobayashi, M | 3 |
| Vu, HT | 2 |
| Kasahara, A | 2 |
| Chen, X | 3 |
| Pham, LT | 1 |
| Kurayoshi, K | 1 |
| Tadokoro, Y | 2 |
| Ueno, M | 2 |
| Todo, T | 2 |
| Nakada, M | 2 |
| Hirao, A | 2 |
| Kundu, M | 1 |
| Das, S | 3 |
| Das, CK | 1 |
| Kulkarni, G | 1 |
| Dhara, D | 1 |
| Mandal, M | 1 |
| Ou, M | 1 |
| Cho, HY | 1 |
| Fu, J | 1 |
| Thein, TZ | 1 |
| Wang, W | 2 |
| Swenson, SD | 1 |
| Minea, RO | 1 |
| Stathopoulos, A | 1 |
| Schönthal, AH | 1 |
| Hofman, FM | 1 |
| Tang, L | 1 |
| Chen, TC | 1 |
| Liu, B | 1 |
| Ding, L | 1 |
| Zhang, L | 3 |
| Wang, S | 3 |
| Wang, Y | 3 |
| Wang, B | 1 |
| Li, L | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 10 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 3 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Zhang, S | 2 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 3 |
| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
| Hammad, N | 1 |
| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
| Xu, X | 1 |
| Zhou, L | 2 |
| Dong, X | 1 |
| Tang, S | 1 |
| Gao, XC | 1 |
| Wei, CH | 1 |
| Zhang, RG | 1 |
| Cai, Q | 1 |
| He, Y | 1 |
| Tong, F | 1 |
| Dong, JH | 1 |
| Wu, G | 1 |
| Dong, XR | 1 |
| Tang, X | 1 |
| Tao, F | 1 |
| Xiang, W | 1 |
| Zhao, Y | 2 |
| Jin, L | 1 |
| Tao, H | 1 |
| Lei, Y | 1 |
| Gan, H | 1 |
| Huang, Y | 1 |
| Chen, Y | 3 |
| Chen, L | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
| Zhang, J | 4 |
| Li, Y | 5 |
| Xue, F | 1 |
| Deng, L | 1 |
| Liu, L | 2 |
| Yan, Z | 2 |
| Meng, J | 1 |
| Chen, G | 2 |
| Anastassiadou, M | 1 |
| Bernasconi, G | 1 |
| Brancato, A | 1 |
| Carrasco Cabrera, L | 1 |
| Greco, L | 1 |
| Jarrah, S | 1 |
| Kazocina, A | 1 |
| Leuschner, R | 1 |
| Magrans, JO | 1 |
| Miron, I | 1 |
| Nave, S | 1 |
| Pedersen, R | 1 |
| Reich, H | 1 |
| Rojas, A | 1 |
| Sacchi, A | 1 |
| Santos, M | 1 |
| Theobald, A | 1 |
| Vagenende, B | 1 |
| Verani, A | 1 |
| Du, L | 1 |
| Liu, X | 1 |
| Ren, Y | 1 |
| Li, J | 7 |
| Li, P | 1 |
| Jiao, Q | 1 |
| Meng, P | 1 |
| Wang, F | 2 |
| Wang, YS | 1 |
| Wang, C | 3 |
| Zhou, X | 2 |
| Hou, J | 1 |
| Zhang, A | 1 |
| Lv, B | 1 |
| Gao, C | 1 |
| Pang, D | 1 |
| Lu, K | 1 |
| Ahmad, NH | 1 |
| Wang, L | 3 |
| Zhu, J | 2 |
| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 8 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
| Zhao, Q | 1 |
| Hu, W | 1 |
| Zhang, Y | 4 |
| Wu, X | 1 |
| Lu, J | 2 |
| Li, M | 1 |
| Li, W | 2 |
| Wu, W | 1 |
| Du, F | 1 |
| Ji, H | 1 |
| Yang, X | 2 |
| Xu, Z | 1 |
| Wan, L | 1 |
| Wen, Q | 1 |
| Cho, CH | 1 |
| Zou, C | 1 |
| Xiao, Z | 1 |
| Liao, J | 1 |
| Su, X | 1 |
| Bi, Z | 1 |
| Su, Q | 1 |
| Huang, H | 2 |
| Wei, Y | 2 |
| Gao, Y | 2 |
| Na, KJ | 1 |
| Choi, H | 1 |
| Oh, HR | 1 |
| Kim, YH | 1 |
| Lee, SB | 1 |
| Jung, YJ | 1 |
| Koh, J | 1 |
| Park, S | 1 |
| Lee, HJ | 1 |
| Jeon, YK | 1 |
| Chung, DH | 1 |
| Paeng, JC | 1 |
| Park, IK | 1 |
| Kang, CH | 1 |
| Cheon, GJ | 1 |
| Kang, KW | 1 |
| Lee, DS | 1 |
| Kim, YT | 1 |
| Pajuelo-Lozano, N | 1 |
| Alcalá, S | 1 |
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| Engelmann, D | 1 |
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| Murr, N | 1 |
| Alpers, M | 1 |
| Singh, KP | 1 |
| Wolkenhauer, O | 1 |
| Heckl, D | 1 |
| Spitschak, A | 1 |
| Pützer, BM | 1 |
| Liao, Y | 1 |
| Cheng, J | 1 |
| Kong, X | 1 |
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| Zhang, M | 4 |
| Zhang, H | 1 |
| Yang, T | 2 |
| Dong, Y | 1 |
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| Liu, Z | 4 |
| Liang, C | 1 |
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| Hu, J | 2 |
| Wang, H | 2 |
| Liu, Y | 5 |
| Mi, Y | 1 |
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| Yan, W | 1 |
| Luo, X | 1 |
| Ning, Q | 1 |
| Chang, X | 2 |
| Zhang, T | 2 |
| Wang, Q | 2 |
| Rathore, MG | 1 |
| Reddy, K | 1 |
| Chen, H | 1 |
| Shin, SH | 1 |
| Ma, WY | 1 |
| Bode, AM | 1 |
| Dong, Z | 1 |
| Mu, W | 1 |
| Liu, C | 3 |
| Gao, F | 1 |
| Qi, Y | 1 |
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| Zhang, X | 5 |
| Cai, X | 1 |
| Ji, RY | 1 |
| Hou, Y | 3 |
| Tian, J | 2 |
| Shi, Y | 1 |
| Ying, S | 1 |
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| Chen, D | 1 |
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| Zhu, ZQ | 1 |
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| Celestrin, CP | 1 |
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| Saad, MJA | 1 |
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| Li, C | 2 |
| Chen, W | 2 |
| Hu, X | 1 |
| Zhang, F | 1 |
| Wei, H | 1 |
| Wang, Z | 1 |
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| Jung, I | 1 |
| Sugimura, H | 2 |
| Stefan-van Staden, RI | 1 |
| Yamada, H | 1 |
| Natsume, H | 1 |
| Iwashita, Y | 1 |
| Szodorai, R | 1 |
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| Validad, MH | 1 |
| Langroudi, FH | 1 |
| Esfandiari, H | 1 |
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| Hassanpour, K | 1 |
| Kurup, SP | 1 |
| Mets-Halgrimson, R | 1 |
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| Zeid, JL | 1 |
| Mets, MB | 1 |
| Rahmani, B | 1 |
| Araujo-Castillo, RV | 1 |
| Culquichicón, C | 1 |
| Solis Condor, R | 1 |
| Efendi, F | 1 |
| Sebayang, SK | 1 |
| Astutik, E | 1 |
| Hadisuyatmana, S | 1 |
| Has, EMM | 1 |
| Kuswanto, H | 1 |
| Foroutan, T | 1 |
| Ahmadi, F | 1 |
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| Khalvati, S | 1 |
| Zhang, Q | 2 |
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3 reviews available for chloroquine and Glioma
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Autophagy in glioma cells: An identity crisis with a clinical perspective.
Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Proteins; Brain Neoplasms; Cell Survival; Chloroqui | 2018 |
Retina and optic nerve.
Topics: Adult; Aged; Angiography; Animals; Blood Circulation; Brain Neoplasms; Carcinogens; Cats; Chloroquin | 1968 |
1 trial available for chloroquine and Glioma
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
35 other studies available for chloroquine and Glioma
| Article | Year |
|---|---|
Therapeutic advantage of targeting lysosomal membrane integrity supported by lysophagy in malignant glioma.
Topics: Autophagy; Chloroquine; Glioblastoma; Glioma; Humans; Lysosomes; Macroautophagy | 2022 |
Magnolol induces cytotoxic autophagy in glioma by inhibiting PI3K/AKT/mTOR signaling.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Chloroquine; Glioma; Insulin | 2023 |
Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate.
Topics: Autophagy; Cell Death; Chloroquine; Glioblastoma; Glioma; Humans; Lysosomes; Monoterpenes; Rolipram; | 2023 |
Baicalein Induces Autophagy and Apoptosis through AMPK Pathway in Human Glioma Cells.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagic Cell Death; | 2019 |
Autophagy-induced KDR/VEGFR-2 activation promotes the formation of vasculogenic mimicry by glioma stem cells.
Topics: Animals; Autophagy; Autophagy-Related Protein 5; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cel | 2017 |
Autophagy inhibition synergizes with calcium mobilization to achieve efficient therapy of malignant gliomas.
Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Calcium; Cell Line, Tumor; Chloroquine; | 2018 |
Nitazoxanide, an antiprotozoal drug, inhibits late-stage autophagy and promotes ING1-induced cell cycle arrest in glioblastoma.
Topics: Animals; Antiprotozoal Agents; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Checkpoints; Cell L | 2018 |
Silencing of mitochondrial NADP(+)-dependent isocitrate dehydrogenase gene enhances glioma radiosensitivity.
Topics: Apoptosis; Autophagy; Chloroquine; Glioma; Humans; Isocitrate Dehydrogenase; Mitochondrial Proteins; | 2013 |
Stimulation of autophagic activity in human glioma cells by anti-proliferative ardipusilloside I isolated from Ardisia pusilla.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Ardisia; Autophagy; Bec | 2014 |
Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells.
Topics: Animals; Antimalarials; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Chloroquine; Dacarb | 2015 |
Heparanase Enhances Tumor Growth and Chemoresistance by Promoting Autophagy.
Topics: Amino Acids; Animals; Antineoplastic Agents; Autophagy; Carcinoma; Cell Division; Cell Line, Tumor; | 2015 |
Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells.
Topics: Adenine; Animals; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chloroquine; Gli | 2016 |
Chloroquine-induced glioma cells death is associated with mitochondrial membrane potential loss, but not oxidative stress.
Topics: Acetylcysteine; Cell Death; Cell Line, Tumor; Chloroquine; Glioma; Humans; Membrane Potential, Mitoc | 2016 |
Chloroquine, an autophagy inhibitor, potentiates the radiosensitivity of glioma initiating cells by inhibiting autophagy and activating apoptosis.
Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Chloroquine; Dose-Response Relationship, Dr | 2016 |
Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway.
Topics: Adenine; Antimutagenic Agents; Apoptosis; Autophagy; Brain Neoplasms; Caspase 3; Cell Hypoxia; Cell | 2017 |
Vaccine therapy with dendritic cells transfected with Il13ra2 mRNA for glioma in mice.
Topics: Animals; Bone Marrow Cells; Brain Neoplasms; Cancer Vaccines; Cell Line, Tumor; Chloroquine; Dendrit | 2010 |
Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells.
Topics: Animals; Antimalarials; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Proliferation; Chloroqui | 2010 |
Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent.
Topics: Antineoplastic Agents; Autophagy; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Chloroquine; | 2010 |
Akt and autophagy cooperate to promote survival of drug-resistant glioma.
Topics: Animals; Autophagy; Cell Line, Tumor; Chloroquine; Drug Synergism; Flow Cytometry; Furans; Glioma; H | 2010 |
Inhibition of autophagy enhances the effects of E1A-defective oncolytic adenovirus dl922-947 against glioma cells in vitro and in vivo.
Topics: Adenine; Adenoviridae; Adenovirus E1A Proteins; Adjuvants, Immunologic; Animals; Autophagy; Cell Lin | 2012 |
Chloroquine or chloroquine-PI3K/Akt pathway inhibitor combinations strongly promote γ-irradiation-induced cell death in primary stem-like glioma cells.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Chloroquine; Drug Synergism; Enzyme Inhibitors; Gamma Rays; | 2012 |
Chloroquine induces the expression of inducible nitric oxide synthase in C6 glioma cells.
Topics: Animals; Cell Line, Tumor; Chloroquine; Dose-Response Relationship, Drug; Enzyme Induction; Gene Exp | 2005 |
Unexpected skin reaction induced by radiotherapy after chloroquine use.
Topics: Antimalarials; Brain Stem Neoplasms; Child; Chloroquine; Female; Glioma; Humans; Radiation Injuries; | 2006 |
Risks and benefits of chloroquine use in anticancer strategies.
Topics: Antimalarials; Brain Stem Neoplasms; Chloroquine; Glioma; Humans; Models, Biological; Radiation-Sens | 2006 |
Enhancing the effect of radionuclide tumor targeting, using lysosomotropic weak bases.
Topics: Amantadine; Ammonium Chloride; Antimalarials; Antipsychotic Agents; Antiviral Agents; Astatine; Carc | 2007 |
Delivery of aclacinomycin A to human glioma cells in vitro by the low-density lipoprotein pathway.
Topics: Aclarubicin; Antibiotics, Antineoplastic; Biological Availability; Cell Division; Chloroquine; Fibro | 1983 |
Down-regulation of opiate receptor in neuroblastoma x glioma NG108-15 hybrid cells. Chloroquine promotes accumulation of tritiated enkephalin in the lysosomes.
Topics: Animals; Cell Line; Chloroquine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glioma; Hybrid | 1984 |
Evidence that secretase cleavage of cell surface Alzheimer amyloid precursor occurs after normal endocytic internalization.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; As | 1995 |
Brefeldin A blocks the response of cultured cells to cholera toxin. Implications for intracellular trafficking in toxin action.
Topics: Adenocarcinoma; Adenylyl Cyclases; Animals; Biological Transport; Brefeldin A; Cell Line; Chloroquin | 1993 |
Biodistribution of 125I-MAb 425 in a human glioma xenograft model: effect of chloroquine.
Topics: Animals; Antibodies, Monoclonal; Brain Neoplasms; Chloroquine; Disease Models, Animal; ErbB Receptor | 1997 |
Intoxication of cultured cells by cholera toxin: evidence for different pathways when bound to ganglioside GM1 or neoganglioproteins.
Topics: Animals; Chloroquine; Cholera Toxin; Cyclic AMP; Endocytosis; G(M1) Ganglioside; Glioma; HeLa Cells; | 1992 |
Protease inhibitors generate cytotoxic fragments from Alzheimer amyloid protein precursor in cDNA-transfected glioma cells.
Topics: Amyloid beta-Protein Precursor; Cells, Cultured; Chloroquine; Cytotoxins; Fluorescent Antibody Techn | 1992 |
Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGF: studies on cultured glioma cells.
Topics: Cells, Cultured; Chloroquine; Epidermal Growth Factor; Glioma; Humans; Iodine Radioisotopes; Lidocai | 1991 |
Metabolism of cholesterol, phosphatidylethanolamine and stearylamine analogues of GM1 ganglioside by rat glioma C6 cells.
Topics: Amines; Animals; Carbohydrate Sequence; Chloroquine; Cholesterol; G(M1) Ganglioside; Glioma; Molecul | 1991 |
Subcellular compartmentation of opioid receptors: modulation by enkephalin and alkaloids.
Topics: Animals; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Chloroquine; Diprenorphine; Enk | 1986 |