Page last updated: 2024-10-24

chloroquine and Giardiasis

chloroquine has been researched along with Giardiasis in 37 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Giardiasis: An infection of the SMALL INTESTINE caused by the flagellated protozoan GIARDIA. It is spread via contaminated food and water and by direct person-to-person contact.

Research Excerpts

ExcerptRelevanceReference
"In a comparative trial, 165 Cuban children with confirmed giardiasis were randomized to receive albendazole (400 mg/day for 5 days), chloroquine (10 mg/kg twice daily for 5 days) or tinidazole (50 mg/kg, as a single dose)."9.10Comparison of chloroquine, albendazole and tinidazole in the treatment of children with giardiasis. ( Almirall, P; Escobedo, AA; Moreira, I; Núñez, FA; Pareja, A; Vega, E, 2003)
"This prospective, open-label, multicenter study assessed the efficacy and tolerability of quinacrine monotherapy (100 mg 3 times per day for 5 days) and albendazole plus chloroquine combination therapy (400 mg twice daily plus 155 mg twice daily for 5 days) in nitroimidazole-refractory giardiasis."8.02Efficacy and Tolerability of Quinacrine Monotherapy and Albendazole Plus Chloroquine Combination Therapy in Nitroimidazole-Refractory Giardiasis: A TropNet Study. ( Bottieau, E; Hatz, C; Kuenzli, E; Mechain, M; Mørch, K; Neumayr, A; Rothe, C; Schunk, M; Soriano Pérez, MJ; Sothmann, P; Sydow, V; Theunissen, C; Van Esbroeck, M, 2021)
"In a comparative trial, 165 Cuban children with confirmed giardiasis were randomized to receive albendazole (400 mg/day for 5 days), chloroquine (10 mg/kg twice daily for 5 days) or tinidazole (50 mg/kg, as a single dose)."5.10Comparison of chloroquine, albendazole and tinidazole in the treatment of children with giardiasis. ( Almirall, P; Escobedo, AA; Moreira, I; Núñez, FA; Pareja, A; Vega, E, 2003)
"This prospective, open-label, multicenter study assessed the efficacy and tolerability of quinacrine monotherapy (100 mg 3 times per day for 5 days) and albendazole plus chloroquine combination therapy (400 mg twice daily plus 155 mg twice daily for 5 days) in nitroimidazole-refractory giardiasis."4.02Efficacy and Tolerability of Quinacrine Monotherapy and Albendazole Plus Chloroquine Combination Therapy in Nitroimidazole-Refractory Giardiasis: A TropNet Study. ( Bottieau, E; Hatz, C; Kuenzli, E; Mechain, M; Mørch, K; Neumayr, A; Rothe, C; Schunk, M; Soriano Pérez, MJ; Sothmann, P; Sydow, V; Theunissen, C; Van Esbroeck, M, 2021)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199031 (83.78)18.7374
1990's0 (0.00)18.2507
2000's1 (2.70)29.6817
2010's4 (10.81)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Neumayr, A1
Schunk, M1
Theunissen, C1
Van Esbroeck, M1
Mechain, M1
Hatz, C1
Mørch, K1
Soriano Pérez, MJ1
Sydow, V1
Sothmann, P1
Kuenzli, E1
Rothe, C1
Bottieau, E1
Carter, ER1
Nabarro, LE1
Hedley, L1
Chiodini, PL1
Escobedo, AA4
Almirall, P4
González-Fraile, E1
Ballesteros, J1
Cimerman, S1
Lalle, M1
Pacheco, F1
Acanda, CZ1
Sánchez, N1
HAMBLY, AS1
SWARTZWELDER, JC1
PAPERMASTER, TC1
Cañete, R1
Rivas, DE1
González, ME1
Brito, K1
Núñez, FA1
Moreira, I1
Vega, E1
Pareja, A1
MAISON, E1
BRUMPT, LC2
ANSARI, AR2
ROSENBAUM, S1
GONDARD, L1
LAMADRID-MONTEMAYOR, F1
GIOSEFFI, G1
COUTELEN, F1
BRETON, A1
BIGUET, J1
DEBLOCK, S1
MULLET, S1
DOBY, JM1
DEY, NC2
KUAR, B2
MARCHESE, MJ1
CANEPA, BC1
ARTIA, R1
SAPP, OL1
BRACKEN, EC1
MONNET, P1
GAUTHIER, J1
KRAJCI LAZARYOVA, M1
BRUCHACOVA, V1
NOVAK, A1
HALSTEAD, SB1
SADUN, EH1
KUZMICKI, R1
SWITALSKA KOWALEWSKA, E1
CARRI, EL1
SCHISANI, JO1
GONDARD, ML1
Wolfe, MS1
von Sonnenburg, F1
Prüfer, L1
Fleischer, NK1
Strik, WO1
Genç, S1
Most, H1
Knight, R1
Schultz, MG1
Hoskins, DW1
Marsden, PD1
Kumar, S1
Nigam, PD1
Sikand, PC1
Werner, GT1
Behrends, R1
Sareen, DK1
Stickl, H1
Wagner, I1
Huggins, D1
Doust, JY1
Haghighi, L1
Kavoussi, KM1
Bengtsson, E1
Boĭko, GF1
Savel'ev, IA1
Zolotarev, AE1

Reviews

9 reviews available for chloroquine and Giardiasis

ArticleYear
Nitroimidazole-refractory giardiasis: a growing problem requiring rational solutions.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2018, Volume: 24, Issue:1

    Topics: Albendazole; Antiprotozoal Agents; Chloroquine; Drug Resistance; Drug Therapy, Combination; Giardia

2018
Efficacy of 5-nitroimidazole compounds for giardiasis in Cuban children: systematic review and meta-analysis.
    Le infezioni in medicina, 2019, Mar-01, Volume: 27, Issue:1

    Topics: Antiprotozoal Agents; Benzimidazoles; Child; Chloroquine; Cuba; Giardiasis; Humans; Nitro Compounds;

2019
Chloroquine: An Old Drug with New Perspective Against Giardiasis.
    Recent patents on anti-infective drug discovery, 2015, Volume: 10, Issue:2

    Topics: Chloroquine; Drug Repositioning; Giardiasis; Humans

2015
The treatment of intestinal protozoan infections.
    The Medical clinics of North America, 1982, Volume: 66, Issue:3

    Topics: Amebicides; Antimalarials; Antiprotozoal Agents; Balantidiasis; Chloroquine; Coccidiosis; Dientamoeb

1982
[Progress in immunodiagnosis and chemotherapy of protozoan infections].
    Der Internist, 1983, Volume: 24, Issue:11

    Topics: Amebiasis; Animals; Antibodies; Babesiosis; Chloroquine; Drug Resistance, Microbial; Giardiasis; Hum

1983
[Lambliasis. Pathogenicity, clinical picture, diagnosis and therapy].
    Medizinische Klinik, 1978, Mar-24, Volume: 73, Issue:12

    Topics: Chloroquine; Diarrhea; England; Female; Gastrointestinal Diseases; Germany; Giardia; Giardiasis; Hum

1978
Drug therapy. Treatment of common parasitic infections of man encountered in the United States. 2.
    The New England journal of medicine, 1972, Oct-05, Volume: 287, Issue:14

    Topics: Amebiasis; Amebicides; Anthelmintics; Antimalarials; Antimony; Benzenesulfonates; Chloroquine; Clono

1972
Intestinal parasites.
    Gut, 1973, Volume: 14, Issue:2

    Topics: Animals; Anthelmintics; Antimony; Chloroquine; Coccidiosis; Diphyllobothriasis; Dysentery, Amebic; E

1973
[Management of parasitic intestinal diseases].
    Revista brasileira de medicina, 1968, Volume: 25, Issue:10

    Topics: Amebicides; Anthelmintics; Balantidiasis; Brazil; Chloroquine; Chloroquinolinols; Dysentery, Amebic;

1968

Trials

2 trials available for chloroquine and Giardiasis

ArticleYear
A randomized, controlled, open-label trial evaluating the efficacy and safety of chloroquine in the treatment of giardiasis in children.
    The West Indian medical journal, 2010, Volume: 59, Issue:6

    Topics: Adolescent; Amebicides; Child; Child, Preschool; Chloroquine; Cuba; Feces; Female; Giardiasis; Human

2010
Comparison of chloroquine, albendazole and tinidazole in the treatment of children with giardiasis.
    Annals of tropical medicine and parasitology, 2003, Volume: 97, Issue:4

    Topics: Adolescent; Albendazole; Antiprotozoal Agents; Child; Child, Preschool; Chloroquine; Feces; Female;

2003

Other Studies

26 other studies available for chloroquine and Giardiasis

ArticleYear
Efficacy and Tolerability of Quinacrine Monotherapy and Albendazole Plus Chloroquine Combination Therapy in Nitroimidazole-Refractory Giardiasis: A TropNet Study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 10-20, Volume: 73, Issue:8

    Topics: Albendazole; Antiprotozoal Agents; Chloroquine; Giardia lamblia; Giardiasis; Humans; Nitroimidazoles

2021
Chloroquine in human giardiasis.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Chloroquine; Giardiasis

1948
The effect of aralen on Giardia lambia infections in children.
    The Journal of parasitology, 1947, Volume: 33, Issue:2

    Topics: Child; Chloroquine; Giardia; Giardiasis; Humans; Protozoan Infections

1947
[The treatment of giardiasis; nivaquine or quinacrine].
    Archives des maladies de l'appareil digestif et des maladies de la nutrition, 1952, Volume: 41, Issue:4

    Topics: Chloroquine; Giardiasis; Quinacrine; Quinolines

1952
Enteritis due to flagellata in children.
    Harefuah, 1952, Apr-15, Volume: 42, Issue:8

    Topics: Child; Chloroquine; Enteritis; Giardiasis; Humans; Infant; Quinacrine

1952
[Superiority of premaline over quinacrine and nivaquine in the treatment of lambliasis].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1953, Volume: 46, Issue:1

    Topics: Aminoquinolines; Chloroquine; Giardiasis; Humans; Quinacrine; Quinolines

1953
Comparative study of chloroquine and amodiaquin in the treatment of giardiasis.
    The American journal of tropical medicine and hygiene, 1954, Volume: 3, Issue:4

    Topics: Amodiaquine; Antimalarials; Chloroquine; Giardiasis

1954
[Therapeutic efficacy of chloroquine apart from its antimalarial properties].
    Bollettino chimico farmaceutico, 1954, Volume: 93, Issue:8

    Topics: Amebiasis; Antimalarials; Cestode Infections; Chloroquine; Dysentery, Amebic; Giardiasis; Humans; Lu

1954
[Comparative study of the effect of quinacrine, nivaquine B and C on giardiasis].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1955, Volume: 48, Issue:3

    Topics: Chloroquine; Giardiasis; Humans; Quinacrine; Quinolines

1955
One day treatment of giardiasis with 7-chloroquinoline.
    Journal of the Indian Medical Association, 1956, Nov-16, Volume: 27, Issue:10

    Topics: Chloroquine; Giardiasis; Humans

1956
One day treatment of giardiasis with 7-chloroquinoline.
    Journal of the Indian Medical Association, 1956, Nov-16, Volume: 27, Issue:10

    Topics: Chloroquine; Giardiasis; Humans

1956
One day treatment of giardiasis with 7-chloroquinoline.
    Journal of the Indian Medical Association, 1956, Nov-16, Volume: 27, Issue:10

    Topics: Chloroquine; Giardiasis; Humans

1956
One day treatment of giardiasis with 7-chloroquinoline.
    Journal of the Indian Medical Association, 1956, Nov-16, Volume: 27, Issue:10

    Topics: Chloroquine; Giardiasis; Humans

1956
[Giardiasis of the bile ducts].
    Prensa medica argentina, 1957, Jan-25, Volume: 44, Issue:4

    Topics: Acridines; Bile Duct Diseases; Bile Ducts; Chloroquine; Giardiasis; Humans

1957
TOXIC PSYCHOSIS DUE TO QUINARCRINE AND CHLOROQUINE.
    JAMA, 1964, Feb-01, Volume: 187

    Topics: Amebiasis; Chloroquine; Giardiasis; Humans; Psychoses, Substance-Induced; Psychotic Disorders; Quina

1964
ANTIHELMINTHIC THERAPY: A SIMPLIFIED APPROACH.
    Southern medical journal, 1964, Volume: 57

    Topics: Amebiasis; Anthelmintics; Ascariasis; Chloroquine; Dysentery, Amebic; Giardiasis; Hookworm Infection

1964
[LAMBLIASIS IN CHILDREN. CELIACA CAUSED BY LAMBLIASIS].
    Archives francaises de pediatrie, 1964, Volume: 21

    Topics: Celiac Disease; Child; Chloroquine; Diagnosis; Giardiasis; Humans; Imidazoles; Intestinal Diseases;

1964
[APROPOS OF LAMBLIASIS IN CHILDHOOD].
    Bratislavske lekarske listy, 1964, Aug-15, Volume: 44

    Topics: Acridines; Adolescent; Child; Chloroquine; Drug Therapy; Giardiasis; Humans; Quinacrine; Quinolines

1964
ALIMENTARY HYPERSENSITIVITY INDUCED BY GIARDIA LAMBLIA; REPORT OF A CASE OF ACUTE MEAT INTOLERANCE.
    Annals of internal medicine, 1965, Volume: 62

    Topics: Abdomen; Abdomen, Acute; Chloroquine; Drug Therapy; Food Hypersensitivity; Giardia lamblia; Giardias

1965
[PRELIMINARY OBSERVATIONS ON THE EFFECT OF ARECHIN POLFA IN LAMBLIASIS].
    Wiadomosci parazytologiczne, 1964, Volume: 10

    Topics: Chloroquine; Drug Therapy; Giardiasis

1964
[Experimental treatment of giardiosis].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1951, Volume: 145, Issue:3-4

    Topics: Chloroquine; Giardiasis; Therapies, Investigational

1951
[Intestinal giardiasis; treatment of nivaquine (3377 R. P.)].
    La Semana medica, 1951, Apr-12, Volume: 58, Issue:15

    Topics: Animals; Chloroquine; Giardiasis; Humans; Intestinal Diseases, Parasitic; Parasites

1951
[Nivaquine is not the medication of choice in lambliasis].
    Archives des maladies de l'appareil digestif et des maladies de la nutrition, 1951, Volume: 40, Issue:12

    Topics: Chloroquine; Choice Behavior; Giardiasis; Quinolines

1951
[The treatment of giardiasis and trichomoniasis with resochin and metronidazole].
    Mikrobiyoloji bulteni, 1976, Volume: 10, Issue:3

    Topics: Child; Chloroquine; Giardiasis; Humans; Intestinal Diseases, Parasitic; Male; Metronidazole; Trichom

1976
'Intesep' in protozoal diarrhoeas.
    The Journal of the Association of Physicians of India, 1972, Volume: 20, Issue:10

    Topics: Adult; Chloroquine; Drug Combinations; Dysentery, Amebic; Female; Giardiasis; Humans; Male; Middle A

1972
[Propagation of intestinal parasites among the inhabitants of northwestern India].
    Medizinische Klinik, 1974, Feb-22, Volume: 69, Issue:8

    Topics: Age Factors; Amebiasis; Ancylostomiasis; Anthelmintics; Ascariasis; Cestode Infections; Chloroquine;

1974
Duodenitis and giardiasis.
    The Journal of tropical medicine and hygiene, 1969, Volume: 72, Issue:11

    Topics: Adult; Chloroquine; Diagnosis, Differential; Duodenal Diseases; Gastrointestinal Diseases; Giardiasi

1969
[Tropical diseases treated at Roslagstulls Hospital].
    Lakartidningen, 1967, Sep-20, Volume: 64, Issue:38

    Topics: Adolescent; Adult; Aged; Amebiasis; Anti-Bacterial Agents; Antimony; Child; Chloroquine; Diethylcarb

1967
[Clinical course and treatment of biliary tract lambliasis].
    Vrachebnoe delo, 1967, Volume: 11

    Topics: Biliary Tract Diseases; Chloroquine; Erythromycin; Female; Giardiasis; Humans; Male

1967