chloroquine has been researched along with Genome Instability in 3 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The gene responsible for Werner syndrome codes for a RecQ-type DNA helicase and is believed to be involved in different aspects of DNA repair, replication, and transcription." | 1.34 | Werner syndrome protein prevents DNA breaks upon chromatin structure alteration. ( Chavez, A; Johnson, FB; Lebel, M; Massip, L; Turaga, RV, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiong, X | 1 |
| Liu, X | 1 |
| Li, H | 1 |
| He, H | 1 |
| Sun, Y | 1 |
| Zhao, Y | 1 |
| Alonso-Villaverde, C | 1 |
| Menéndez, JA | 1 |
| Joven, J | 1 |
| Turaga, RV | 1 |
| Massip, L | 1 |
| Chavez, A | 1 |
| Johnson, FB | 1 |
| Lebel, M | 1 |
3 other studies available for chloroquine and Genome Instability
| Article | Year |
|---|---|
Ribosomal protein S27-like regulates autophagy via the β-TrCP-DEPTOR-mTORC1 axis.
Topics: Animals; Apoptosis; Autophagy; beta-Transducin Repeat-Containing Proteins; Breast Neoplasms; Cell Li | 2018 |
Metabolic stress in infected cells may represent a therapeutic target for human immunodeficiency virus infection.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Chloroquine; Genomic Instability; HIV Infections; HIV-1 | 2013 |
Werner syndrome protein prevents DNA breaks upon chromatin structure alteration.
Topics: Animals; Bloom Syndrome; Cell Line; Cell Line, Tumor; Cellular Senescence; Chloroquine; Chromatin; D | 2007 |