Page last updated: 2024-10-24

chloroquine and Fungal Diseases

chloroquine has been researched along with Fungal Diseases in 6 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Research Excerpts

ExcerptRelevanceReference
" Chloroquine and hydroxychloroquine, with an original indication to prevent or cure malaria, have been successfully used to treat several infectious (HIV, Q fever, Whipple's disease, fungal infections), rheumatological (systemic lupus erythematosus, antiphospholipid antibody syndrome, rheumatoid arthritis, Sjögren's syndrome), and other immunological diseases."4.98Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review. ( Koudriavtseva, T; Plantone, D, 2018)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karad, SC1
Purohit, VB1
Thakor, P1
Thakkar, VR1
Raval, DK1
Wu, S1
Wang, Y1
Liu, N1
Dong, G1
Sheng, C1
Plantone, D1
Koudriavtseva, T1
Kabbage, M1
Williams, B1
Dickman, MB1
Rolain, JM1
Colson, P1
Raoult, D1
Vischer, WA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Proflaxis for Healthcare Professionals Using Hydroxychloroquine Plus Vitamin Combining Vitamins C, D and Zinc During COVID-19 Pandemia: An Observational Study[NCT04326725]80 participants (Anticipated)Observational2020-03-20Active, not recruiting
Rapid Development and Implementation of a Remote ECG-monitored Prospective Randomized Clinical Trial During a Pandemic: Hydroxychloroquine Prophylaxis in COVID-19 Household Contacts[NCT04652648]Phase 454 participants (Actual)Interventional2020-05-27Completed
A Randomized Trial of Efficacy and Safety of an Early OUTpatient Treatment of COVID-19 in Patients With Risk Factor for Poor Outcome: a Strategy to Prevent Hospitalization[NCT04365582]Phase 30 participants (Actual)Interventional2020-05-07Withdrawn (stopped due to The PI decided.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for chloroquine and Fungal Diseases

ArticleYear
Tackling Fungal Resistance by Biofilm Inhibitors.
    Journal of medicinal chemistry, 2017, 03-23, Volume: 60, Issue:6

    Topics: Animals; Antifungal Agents; Biofilms; Drug Discovery; Drug Resistance, Fungal; Fungi; Humans; Models

2017
Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review.
    Clinical drug investigation, 2018, Volume: 38, Issue:8

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antimalarials; Antineoplastic Agents; Antirheumatic

2018
Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century.
    International journal of antimicrobial agents, 2007, Volume: 30, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antiviral Agents; Bacterial Infecti

2007
Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century.
    International journal of antimicrobial agents, 2007, Volume: 30, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antiviral Agents; Bacterial Infecti

2007
Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century.
    International journal of antimicrobial agents, 2007, Volume: 30, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antiviral Agents; Bacterial Infecti

2007
Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century.
    International journal of antimicrobial agents, 2007, Volume: 30, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antiviral Agents; Bacterial Infecti

2007

Other Studies

3 other studies available for chloroquine and Fungal Diseases

ArticleYear
Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities.
    European journal of medicinal chemistry, 2016, Apr-13, Volume: 112

    Topics: Anti-Infective Agents; Antimalarials; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi;

2016
Cell death control: the interplay of apoptosis and autophagy in the pathogenicity of Sclerotinia sclerotiorum.
    PLoS pathogens, 2013, Volume: 9, Issue:4

    Topics: Adenine; Androstadienes; Antifungal Agents; Apoptosis; Arabidopsis; Ascomycota; Autophagy; Chloroqui

2013
Antimicrobial activity of the leprostatic drug 3-(p-chloranilino)-10-(p-chlorphenyl-2,10-dihydro-2-(isopropylimino)-phenazine (G 30'320, B. 663).
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:5

    Topics: Animals; Antitubercular Agents; Aspergillosis; Candidiasis; Chloroquine; Cricetinae; Disease Models,

1970