chloroquine has been researched along with Frontotemporal Lobar Degeneration in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Frontotemporal Lobar Degeneration: Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Capell, A | 1 |
| Liebscher, S | 1 |
| Fellerer, K | 1 |
| Brouwers, N | 1 |
| Willem, M | 1 |
| Lammich, S | 1 |
| Gijselinck, I | 1 |
| Bittner, T | 1 |
| Carlson, AM | 1 |
| Sasse, F | 1 |
| Kunze, B | 1 |
| Steinmetz, H | 1 |
| Jansen, R | 1 |
| Dormann, D | 1 |
| Sleegers, K | 1 |
| Cruts, M | 1 |
| Herms, J | 1 |
| Van Broeckhoven, C | 1 |
| Haass, C | 1 |
1 other study available for chloroquine and Frontotemporal Lobar Degeneration
| Article | Year |
|---|---|
Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase.
Topics: Alkalies; Amiodarone; Animals; Animals, Newborn; Autophagy-Related Protein 5; Bepridil; Blotting, No | 2011 |