chloroquine has been researched along with Fetal Death in 10 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a cohort of pregnant women enrolled at first antenatal clinic visit in rural Malawi, we evaluated reported fever, determined parasitemia, and placed the women on antimalarial regimens containing chloroquine (CQ) or mefloquine (MQ)." | 7.69 | Malaria treatment and prevention in pregnancy: indications for use and adverse events associated with use of chloroquine or mefloquine. ( Breman, JG; Heymann, DL; Khoromana, CO; Slutsker, L; Steketee, RW; Wirima, JJ, 1996) |
| "Although the use of chloroquine (C) and hydroxychloroquine (HC) in the treatment of malaria prophylaxis during pregnancy is probably safe, the use of much higher doses for treatment of systemic lupus erythematosus (SLE) and rheumatoid arthritis during pregnancy has been controversial." | 7.68 | Pregnancy outcome following first trimester exposure to chloroquine. ( Buskila, D; Gladman, DD; Koren, G; Levy, M; Urowitz, MB, 1991) |
| " In a cohort of pregnant women enrolled at first antenatal clinic visit in rural Malawi, we evaluated reported fever, determined parasitemia, and placed the women on antimalarial regimens containing chloroquine (CQ) or mefloquine (MQ)." | 3.69 | Malaria treatment and prevention in pregnancy: indications for use and adverse events associated with use of chloroquine or mefloquine. ( Breman, JG; Heymann, DL; Khoromana, CO; Slutsker, L; Steketee, RW; Wirima, JJ, 1996) |
| "Although the use of chloroquine (C) and hydroxychloroquine (HC) in the treatment of malaria prophylaxis during pregnancy is probably safe, the use of much higher doses for treatment of systemic lupus erythematosus (SLE) and rheumatoid arthritis during pregnancy has been controversial." | 3.68 | Pregnancy outcome following first trimester exposure to chloroquine. ( Buskila, D; Gladman, DD; Koren, G; Levy, M; Urowitz, MB, 1991) |
| " All drug dosing was performed under supervision by the study team, making this an evaluation of intervention efficacy (excluding the role of patient compliance)." | 2.68 | Objectives and methodology in a study of malaria treatment and prevention in pregnancy in rural Malawi: The Mangochi Malaria Research Project. ( Breman, JG; Heymann, DL; Khoromana, CO; Slutsker, WL; Steketee, RW; Wirima, JJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Flici, O | 1 |
| Tadjerouni, A | 1 |
| Leroy, F | 1 |
| Teys, JP | 1 |
| Hubinont, PO | 1 |
| Nyirjesy, P | 1 |
| Kavasya, T | 1 |
| Axelrod, P | 1 |
| Fischer, PR | 1 |
| Steketee, RW | 2 |
| Wirima, JJ | 2 |
| Slutsker, L | 1 |
| Khoromana, CO | 2 |
| Heymann, DL | 2 |
| Breman, JG | 2 |
| Slutsker, WL | 1 |
| Martínez-Rueda, JO | 1 |
| Arce-Salinas, CA | 1 |
| Kraus, A | 1 |
| Alcocer-Varela, J | 1 |
| Alarcón-Segovia, D | 1 |
| Fontes, CJ | 1 |
| Munhoz, S | 1 |
| Toan, NG | 1 |
| Levy, M | 1 |
| Buskila, D | 1 |
| Gladman, DD | 1 |
| Urowitz, MB | 1 |
| Koren, G | 1 |
| Parke, AL | 1 |
| Harrison, KA | 1 |
| Ibeziako, PA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Comparative Study of Mefloquine and Sulphadoxine-pyrimethamine as Prophylaxis Against Malaria in Pregnant Human Immunodeficiency Virus Positive Patients[NCT02524444] | Phase 1 | 142 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chloroquine and Fetal Death
| Article | Year |
|---|---|
[Malaria in pregnant women. Presentation of 2 cases and review of the literature].
Topics: Abortion, Spontaneous; Acute Kidney Injury; Adult; Anemia, Hemolytic; Antimalarials; Brain Diseases; | 1982 |
1 trial available for chloroquine and Fetal Death
| Article | Year |
|---|---|
Objectives and methodology in a study of malaria treatment and prevention in pregnancy in rural Malawi: The Mangochi Malaria Research Project.
Topics: Antimalarials; Chloroquine; Female; Fetal Death; Follow-Up Studies; Humans; Infant, Low Birth Weight | 1996 |
8 other studies available for chloroquine and Fetal Death
| Article | Year |
|---|---|
Malaria during pregnancy: neonatal morbidity and mortality and the efficacy of chloroquine chemoprophylaxis.
Topics: Birth Weight; Chloroquine; Drug Resistance; Female; Fetal Death; Humans; Infant, Newborn; Malaria, F | 1993 |
Malaria treatment and prevention in pregnancy: indications for use and adverse events associated with use of chloroquine or mefloquine.
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Female; Fetal Death; Fever; Humans; Malaria, Falcipar | 1996 |
Factors associated with fetal losses in severe systemic lupus erythematosus.
Topics: Adult; Analysis of Variance; Azathioprine; Case-Control Studies; Chloroquine; Cohort Studies; Congen | 1996 |
Severe falciparum malaria with hyperparasitaemia: management without exchange blood transfusion.
Topics: Adolescent; Animals; Antimalarials; Chloroquine; Female; Fetal Death; Humans; Malaria, Falciparum; P | 1996 |
[Malaria and pregnancy].
Topics: Adult; Chloroquine; Female; Fetal Death; Humans; Malaria, Falciparum; Malaria, Vivax; Pregnancy; Pre | 1992 |
Pregnancy outcome following first trimester exposure to chloroquine.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adolescent; Adult; Arthritis, Rheumatoid; Chloro | 1991 |
Antimalarial drugs, systemic lupus erythematosus and pregnancy.
Topics: Abortion, Spontaneous; Antimalarials; Chloroquine; Female; Fetal Death; Humans; Hydroxychloroquine; | 1988 |
Maternal anaemia and fetal birthweight.
Topics: Anemia; Anemia, Sickle Cell; Birth Weight; Blood Transfusion; Body Height; Chloroquine; Embryonic an | 1973 |