chloroquine has been researched along with Fabry Disease in 10 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Fabry Disease: An X-linked inherited metabolic disease caused by a deficiency of lysosomal ALPHA-GALACTOSIDASE A. It is characterized by intralysosomal accumulation of globotriaosylceramide and other GLYCOSPHINGOLIPIDS in blood vessels throughout the body leading to multi-system complications including renal, cardiac, cerebrovascular, and skin disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following dose-response studies, 0." | 1.62 | Chloroquine may induce endothelial injury through lysosomal dysfunction and oxidative stress. ( Barreto, FC; Biagini, G; Bosquetti, B; Budag, J; da Cunha, RS; Gregório, P; Ortiz, A; Sánchez-Niño, MD; Stinghen, AEM, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hanneman, K | 1 |
| Alberdi, HV | 1 |
| Karur, GR | 1 |
| Tselios, K | 1 |
| Harvey, PJ | 1 |
| Gladman, DD | 1 |
| Akhtari, S | 1 |
| Osuntokun, T | 1 |
| Wald, RM | 1 |
| Thavendiranathan, P | 1 |
| Butany, J | 1 |
| Urowitz, MB | 1 |
| Gregório, P | 1 |
| da Cunha, RS | 1 |
| Biagini, G | 1 |
| Bosquetti, B | 1 |
| Budag, J | 1 |
| Ortiz, A | 1 |
| Sánchez-Niño, MD | 1 |
| Barreto, FC | 1 |
| Stinghen, AEM | 1 |
| Navratil, M | 1 |
| Ivković Jureković, I | 1 |
| Müller-Höcker, J | 1 |
| Schmid, H | 1 |
| Weiss, M | 1 |
| Dendorfer, U | 1 |
| Braun, GS | 1 |
| Linthorst, GE | 1 |
| Hollak, CE | 1 |
| Albay, D | 1 |
| Adler, SG | 1 |
| Philipose, J | 1 |
| Calescibetta, CC | 1 |
| Romansky, SG | 1 |
| Cohen, AH | 1 |
| Pieroni, M | 1 |
| Bellocci, F | 1 |
| Crea, F | 1 |
| D'Amico, DJ | 1 |
| Kenyon, KR | 1 |
| Inagaki, M | 1 |
| Katsumoto, T | 1 |
| Nanba, E | 1 |
| Ohno, K | 1 |
| Suehiro, S | 1 |
| Takeshita, K | 1 |
| Bron, AJ | 1 |
10 other studies available for chloroquine and Fabry Disease
| Article | Year |
|---|---|
Antimalarial-Induced Cardiomyopathy Resembles Fabry Disease on Cardiac MRI.
Topics: Adult; Aged; Antimalarials; Biopsy; Cardiomyopathies; Cardiotoxicity; Chloroquine; Diagnosis, Differ | 2020 |
Chloroquine may induce endothelial injury through lysosomal dysfunction and oxidative stress.
Topics: Cell Survival; Cells, Cultured; Chloroquine; COVID-19 Drug Treatment; Endothelial Cells; Endothelium | 2021 |
Chloroquine Toxicity Misdiagnosed as Fabry Disease Associated with Systemic Lupus Erythematosus and Hashimoto Thyroiditis.
Topics: Adolescent; Antirheumatic Agents; Chloroquine; Diagnostic Errors; Fabry Disease; Female; Hashimoto D | 2017 |
Chloroquine-induced phospholipidosis of the kidney mimicking Fabry's disease: case report and review of the literature.
Topics: alpha-Galactosidase; Chloroquine; Diagnosis, Differential; Fabry Disease; Female; Humans; Hypertensi | 2003 |
Chloroquine-induced phospholipidosis of the kidney mimicking Fabry's disease.
Topics: alpha-Galactosidase; Antirheumatic Agents; Chloroquine; Diagnosis, Differential; Fabry Disease; Fema | 2003 |
Chloroquine-induced lipidosis mimicking Fabry disease.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Diagnosis, Differential; Fabry Disease; Fe | 2005 |
Letter by Pieroni et al regarding article, "Contrast-enhanced magnetic resonance imaging of a patient with chloroquine-induced cardiomyopathy confirmed by endomyocardial biopsy".
Topics: Cardiomyopathies; Chloroquine; Contrast Media; Diagnosis, Differential; Endocardium; Fabry Disease; | 2007 |
Drug-induced lipidoses of the cornea and conjunctiva.
Topics: Amiodarone; Amodiaquine; Chloroquine; Conjunctival Diseases; Corneal Diseases; Fabry Disease; Female | 1981 |
Lysosomal glycosphingolipid storage in chloroquine-induced alpha-galactosidase-deficient human endothelial cells with transformation by simian virus 40: in vitro model of Fabry disease.
Topics: Cell Transformation, Viral; Chloroquine; Clomipramine; Endothelium, Vascular; Fabry Disease; Galacto | 1993 |
Vortex patterns of the corneal epithelium.
Topics: Chloroquine; Cornea; Corneal Dystrophies, Hereditary; Corneal Transplantation; Epithelium; Fabry Dis | 1973 |