chloroquine has been researched along with Experimental Hepatoma in 15 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "adjuvant arthritis, were found to increase tumour cell 3H-TdR incorporation, compared to macrophages from nonarthritic rats." | 1.26 | Antirheumatic drugs and macrophage function: effects on tumour cell growth in vitro. ( Arrigoni-Martelli, E; Binderup, L; Bramm, E, 1982) |
| "Treatment with chloroquine, a lysosomal enzyme inhibitor, resulted in a large increase of cell-associated insulin compared to control cells." | 1.26 | In vitro characterization of the mechanism of insulin degradation and the effect of chloroquine. ( Seeman, M; Tsai, JS, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (80.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, X | 1 |
| De Vera, ME | 1 |
| Buchser, WJ | 1 |
| Romo de Vivar Chavez, A | 1 |
| Loughran, P | 1 |
| Beer Stolz, D | 1 |
| Basse, P | 1 |
| Wang, T | 1 |
| Van Houten, B | 1 |
| Zeh, HJ | 1 |
| Lotze, MT | 1 |
| Nato, F | 1 |
| Aubery, M | 1 |
| Bourrillon, R | 1 |
| Hare, JF | 1 |
| Huston, M | 1 |
| Binderup, L | 1 |
| Bramm, E | 1 |
| Arrigoni-Martelli, E | 1 |
| Tsai, JS | 1 |
| Seeman, M | 1 |
| Quintart, J | 2 |
| Baudhuin, P | 2 |
| Leroy-Houyet, MA | 1 |
| Trouet, A | 1 |
| Steinebach, OM | 1 |
| Wolterbeek, BT | 1 |
| de Vries, CP | 1 |
| van Haeften, TW | 1 |
| Opara, EC | 1 |
| van der Veen, EA | 1 |
| Sorimachi, K | 3 |
| Yasumura, Y | 3 |
| Lotan, RM | 1 |
| Lender, M | 1 |
| Blake, AD | 1 |
| Strader, CD | 1 |
| Smith, RM | 1 |
| Laudenslager, NH | 1 |
| Shah, N | 1 |
| Jarett, L | 1 |
| Okayasu, T | 2 |
15 other studies available for chloroquine and Experimental Hepatoma
| Article | Year |
|---|---|
Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression.
Topics: Animals; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Chloroquine; Female; HMGB1 Prot | 2012 |
Approach to the mechanism of Zajdela's hepatoma cell growth inhibition induced by concanavalin A and phytohaemagglutinin.
Topics: alpha-Fetoproteins; Animals; Asialoglycoproteins; Cell Division; Cell Survival; Chloroquine; Concana | 1982 |
Degradation of surface-labeled hepatoma membrane polypeptides: effect of inhibitors.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Iodine Radioisotopes; Liver Neoplasms, Experimen | 1984 |
Antirheumatic drugs and macrophage function: effects on tumour cell growth in vitro.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chloroquine; Female; Levamiso | 1982 |
In vitro characterization of the mechanism of insulin degradation and the effect of chloroquine.
Topics: Animals; Cell Line; Chloroquine; Chromatography, Gel; In Vitro Techniques; Insulin; Insulin Antibodi | 1981 |
Accumulation of chloroquine by hepatoma cells as a function of the cell cycle [proceedings].
Topics: Animals; Cell Cycle; Cell Line; Chloroquine; Liver Neoplasms, Experimental; Lysosomes | 1978 |
Endocytosis and chloroquine accumulation during the cell cycle of hepatoma cells in culture.
Topics: Animals; Cell Cycle; Chloroquine; Culture Techniques; Dextrans; Endocytosis; Horseradish Peroxidase; | 1979 |
Metallothionein biodegradation in rat hepatoma cells: a compartmental analysis aided 35S-radiotracer study.
Topics: Animals; Biological Transport; Biotransformation; Cell Survival; Chloroquine; Copper; Cytosol; Kinet | 1992 |
Influence of inhibition of insulin degradation on Scatchard analysis in H35 rat hepatoma cells.
Topics: Animals; Bacitracin; Binding, Competitive; Cell Line; Chloroquine; Insulin; Liver Neoplasms, Experim | 1991 |
Regulation of alkaline phosphatase activity in rat hepatoma cells. Effects of serum proteins, cycloheximide, actinomycin D, chloroquine, dinitrophenol and potassium cyanide.
Topics: Alkaline Phosphatase; Animals; Blood; Blood Proteins; Cell Line; Chloroquine; Cycloheximide; Dactino | 1986 |
Insulin receptor regulation in minimal deviation hepatoma cell line.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Cell Membrane; Chloroquine; Insulin; Lectins; | 1986 |
Potentiation of specific association of insulin with HepG2 cells by phorbol esters.
Topics: Animals; Cell Line; Chloroquine; Drug Synergism; Humans; Insulin; Liver Neoplasms, Experimental; Mon | 1986 |
Insulin binding and processing by H4IIEC3 hepatoma cells: ultrastructural and biochemical evidence for a unique route of internalization and processing.
Topics: Animals; Cell Line; Chloroquine; Insulin; Kinetics; Liver Neoplasms, Experimental; Microscopy, Elect | 1987 |
Increase in insulin binding affinity by chloroquine in cultured rat hepatoma cells.
Topics: Animals; Cell Membrane; Cells, Cultured; Chloroquine; Insulin; Kinetics; Liver Neoplasms, Experiment | 1987 |
Inhibitory effect of chloroquine on concanavalin A internalization into cell monolayer culture.
Topics: Animals; Binding, Competitive; Cell Line; Chloroquine; Concanavalin A; Kinetics; Liver Neoplasms, Ex | 1985 |