Page last updated: 2024-10-24

chloroquine and Epithelial Ovarian Cancer

chloroquine has been researched along with Epithelial Ovarian Cancer in 3 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Research Excerpts

ExcerptRelevanceReference
"We tested a panel of 28 epithelial ovarian cancer (EOC) cell lines with itraconazole to define its spectrum of activity."5.72Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer. ( Bowering, V; Bruce, JP; Cabanero, M; Chen, EX; Colombo, I; Dhani, NC; Garg, S; Gill, S; Joshua, AM; Ketela, T; Koritzinsky, M; Lheureux, S; Li, X; Li, ZJ; Madariaga, A; Mandilaras, V; Marastoni, S; Nair, SN; Oza, AM; Pesic, A; Pintilie, M; Rottapel, R; Shalev, Z; Wang, L; Wouters, BG; Zhang, W, 2022)
"We tested a panel of 28 epithelial ovarian cancer (EOC) cell lines with itraconazole to define its spectrum of activity."1.72Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer. ( Bowering, V; Bruce, JP; Cabanero, M; Chen, EX; Colombo, I; Dhani, NC; Garg, S; Gill, S; Joshua, AM; Ketela, T; Koritzinsky, M; Lheureux, S; Li, X; Li, ZJ; Madariaga, A; Mandilaras, V; Marastoni, S; Nair, SN; Oza, AM; Pesic, A; Pintilie, M; Rottapel, R; Shalev, Z; Wang, L; Wouters, BG; Zhang, W, 2022)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's3 (100.00)2.80

Authors

AuthorsStudies
Ovejero-Sánchez, M1
Rubio-Heras, J1
Vicente de la Peña, MDC1
San-Segundo, L1
Pérez-Losada, J1
González-Sarmiento, R1
Herrero, AB1
Marastoni, S1
Madariaga, A1
Pesic, A1
Nair, SN1
Li, ZJ1
Shalev, Z1
Ketela, T1
Colombo, I1
Mandilaras, V1
Cabanero, M1
Bruce, JP1
Li, X1
Garg, S1
Wang, L1
Chen, EX1
Gill, S1
Dhani, NC1
Zhang, W2
Pintilie, M1
Bowering, V1
Koritzinsky, M1
Rottapel, R1
Wouters, BG1
Oza, AM1
Joshua, AM1
Lheureux, S1
Pan, Y1
Zhou, J1
Yan, L1
Lu, M1
Dai, Y1
Zhou, H1
Zhang, S1
Yang, J1

Other Studies

3 other studies available for chloroquine and Epithelial Ovarian Cancer

ArticleYear
Chloroquine-Induced DNA Damage Synergizes with Nonhomologous End Joining Inhibition to Cause Ovarian Cancer Cell Cytotoxicity.
    International journal of molecular sciences, 2022, Jul-07, Volume: 23, Issue:14

    Topics: Carcinoma, Ovarian Epithelial; Chloroquine; DNA Breaks, Double-Stranded; DNA Damage; DNA End-Joining

2022
Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer.
    Cancer research communications, 2022, Volume: 2, Issue:5

    Topics: Antifungal Agents; Antineoplastic Agents; Carcinoma, Ovarian Epithelial; Chloroquine; Drug Repositio

2022
The Sonic Hedgehog signaling pathway regulates autophagy and migration in ovarian cancer.
    Cancer medicine, 2021, Volume: 10, Issue:13

    Topics: Animals; Autophagic Cell Death; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Movement; Chlo

2021