chloroquine has been researched along with Endometrial Neoplasms in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Endometrial Neoplasms: Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.
Excerpt | Relevance | Reference |
---|---|---|
"However, the role of autophagy in endometrial cancer has not yet been established." | 1.42 | The anti-malarial chloroquine suppresses proliferation and overcomes cisplatin resistance of endometrial cancer cells via autophagy inhibition. ( Arimoto, T; Fujii, T; Fukuda, T; Ikeda, Y; Inaba, K; Kashiyama, T; Kawana, K; Kuramoto, H; Miyasaka, A; Oda, K; Osuga, Y; Sone, K; Tanikawa, M; Wada-Hiraike, O; Yano, T, 2015) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Liu, S | 1 |
Li, X | 1 |
Fukuda, T | 1 |
Oda, K | 1 |
Wada-Hiraike, O | 1 |
Sone, K | 1 |
Inaba, K | 1 |
Ikeda, Y | 1 |
Miyasaka, A | 1 |
Kashiyama, T | 1 |
Tanikawa, M | 1 |
Arimoto, T | 1 |
Kuramoto, H | 1 |
Yano, T | 1 |
Kawana, K | 1 |
Osuga, Y | 1 |
Fujii, T | 1 |
2 other studies available for chloroquine and Endometrial Neoplasms
Article | Year |
---|---|
Autophagy inhibition enhances sensitivity of endometrial carcinoma cells to paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Line, Tu | 2015 |
The anti-malarial chloroquine suppresses proliferation and overcomes cisplatin resistance of endometrial cancer cells via autophagy inhibition.
Topics: Antimalarials; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cell Cycle; Cel | 2015 |