chloroquine has been researched along with Edema in 22 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine (CQ) is known to be an anti-malarial drug; however, additional protective functions of CQ have been discovered." | 1.62 | Chloroquine attenuates thymic stromal lymphopoietin production via suppressing caspase-1 signaling in mast cells. ( Han, NR; Ko, SG; Moon, PD; Park, HJ, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (90.91) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Han, NR | 1 |
| Ko, SG | 1 |
| Moon, PD | 1 |
| Park, HJ | 1 |
| Reis, PA | 1 |
| Estato, V | 1 |
| da Silva, TI | 1 |
| d'Avila, JC | 1 |
| Siqueira, LD | 1 |
| Assis, EF | 1 |
| Bozza, PT | 1 |
| Bozza, FA | 1 |
| Tibiriça, EV | 1 |
| Zimmerman, GA | 1 |
| Castro-Faria-Neto, HC | 1 |
| VAN CAUWENBERGE, H | 2 |
| LECOMTE, J | 2 |
| LAPIERE, C | 1 |
| LAPIERRE, C | 1 |
| PALEMVLIERS, M | 1 |
| PETRANYI, G | 1 |
| ADAM, M | 1 |
| HOUBA, V | 1 |
| STOJAN, B | 1 |
| DELBARRE, F | 1 |
| BUU-HOUI, NP | 1 |
| JACQUIGNON, P | 1 |
| BROUILHET, H | 1 |
| KAHAN, A | 1 |
| MARTY, M | 1 |
| HERTZBERG, R | 1 |
| Nowinski, T | 1 |
| Bernardino, V | 1 |
| Naidoff, M | 1 |
| Parrish, R | 1 |
| Yoshioka, A | 1 |
| Miyachi, Y | 1 |
| Imamura, S | 1 |
| Frame, JD | 1 |
| Baldwin, JM | 1 |
| Gocke, DJ | 1 |
| Troup, JM | 1 |
| Thiel, HJ | 1 |
| Okegawa, T | 1 |
| Nakanishi, H | 1 |
| Shimamoto, K | 1 |
| Suzuki, Y | 1 |
| Ito, I | 1 |
| Ito, M | 1 |
| Yamagami, I | 1 |
| Swingle, KF | 1 |
| Fujihira, E | 1 |
| Otomo, S | 1 |
| Sota, K | 1 |
| Nakazawa, M | 1 |
| François, J | 1 |
| Maudgal, MC | 1 |
| Blount, RE | 1 |
| Stevenson, DD | 1 |
| McGerity, JL | 1 |
| Bailey, DM | 1 |
| Gleiser, CA | 1 |
| Dukes, TW | 1 |
| Lawwill, T | 1 |
| Read, WK | 1 |
| Bay, WW | 1 |
| Brown, RS | 1 |
| Sancilio, LF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Early Atorvastatin Treatment During the Acute Phase of Stroke on Immunoinflammatory Markers and Outcome in Patients With Acute Ischemic Stroke Classified as LAAS According TOAST Classification[NCT02225834] | Phase 4 | 50 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chloroquine and Edema
| Article | Year |
|---|---|
[Epithelium of the cornea and its significance for transparency].
Topics: Aerobiosis; Air; Chloroquine; Cornea; Corneal Dystrophies, Hereditary; Corneal Opacity; Edema; Epith | 1974 |
21 other studies available for chloroquine and Edema
| Article | Year |
|---|---|
Chloroquine attenuates thymic stromal lymphopoietin production via suppressing caspase-1 signaling in mast cells.
Topics: Animals; Calcimycin; Caspase 1; Caspase Inhibitors; Cell Line; Chloroquine; Cytokines; Ear Diseases; | 2021 |
Statins decrease neuroinflammation and prevent cognitive impairment after cerebral malaria.
Topics: Animals; Brain; CD11b Antigen; Chemokines; Chloroquine; Cognition Disorders; Cytokines; Edema; Endot | 2012 |
[Effect of chloroquine on edema induced by ovalbumin and dextran and on Ambrose and Eds test in rat].
Topics: Animals; Chloroquine; Dextrans; Edema; Hypersensitivity; Immune System Diseases; Ovalbumin; Rats | 1958 |
[Attempt at interpretation of the mode of action of chloroquine in the treatment of inflammatory infections].
Topics: Chloroquine; Edema | 1959 |
[TREATMENT OF LUPUS-NEPHROPATHIES WITH 6-MERCAPTOPURINE].
Topics: Albuminuria; Chloroquine; Diuretics; Edema; Glomerulonephritis; Humans; Lupus Erythematosus, Discoid | 1964 |
[EFFECT OF RESOCHIN ON STERILE AND INFECTIOUS EXPERIMENTAL INFLAMMATION].
Topics: Anti-Infective Agents; Chloroquine; Edema; Granuloma; Inflammation; Neisseria; Penicillins; Rats; Re | 1964 |
[NON-STEROID ANTI-INFLAMMATORY AGENTS. I. DERIVATIVES OF 4- AND 5-AMINOSALICYLIC ACIDS].
Topics: 4-Aminobenzoic Acid; Aminopyrine; Aminosalicylic Acid; Aminosalicylic Acids; Analgesics; Analgesics, | 1964 |
Corneal oedema due to "chloroquine".
Topics: Chloroquine; Cornea; Corneal Diseases; Corneal Edema; Disease; Edema; Humans | 1960 |
Ocular involvement in lupus erythematosus profundus (panniculitis).
Topics: Adult; Blepharoptosis; Chloroquine; Edema; Exophthalmos; Eyelid Diseases; Female; Humans; Lupus Eryt | 1982 |
The mechanism of the inhibitory effects of antimalarials on UV-induced skin inflammation in mice.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chloroquine; Ear, External; Edema; Female; Inflammatio | 1988 |
Lassa fever, a new virus disease of man from West Africa. I. Clinical description and pathological findings.
Topics: Acute Disease; Adult; Aged; Autopsy; Back Pain; Blood; Blood Cell Count; Chloroquine; Edema; Female; | 1970 |
The antiphlogistic effects of chloroquine diphosphate and diorotate. I. Anti-acetylcholine, -histamine and -serotonin effects in vitro and in vivo.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Chloroquine; Dogs; Edema; Female; Granuloma; Guine | 1966 |
[Changes of mucopolysaccharase, protease and collagenolytic activities in rats with adjuvant arthritis and the effects of various anti-inflammatory drugs].
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Azathioprine; Barbiturates; Chloroquine; Collagen; Cyc | 1973 |
Interaction of chloroquine and carrageenan.
Topics: Animals; Carrageenan; Chloroquine; Drug Interactions; Edema; Foot; Hydrogen-Ion Concentration; Male; | 1974 |
[Anti-inflammatory activities of compounds related to anthranilic acid. II. On acridine mono- and dicarboxylic, and oxo-acridan monocarboxylic acid derivatives].
Topics: Acridines; Aminopyrine; Animals; Anti-Inflammatory Agents; Carboxylic Acids; Carrageenan; Cattle; Ch | 1971 |
Experimental chronic chloroquine intoxication.
Topics: Animals; Brain; Chloroquine; Corneal Dystrophies, Hereditary; Edema; Fluorescence; Kidney; Liver; Lu | 1967 |
Management of chloroquine resistant falciparum malaria.
Topics: Adult; Brain Diseases; Chloroquine; Dapsone; Dexamethasone; Drug Resistance, Microbial; Edema; Human | 1967 |
Simultaneous drug reactions in the same patient. Chloroquine-Primaquine sensitivity.
Topics: Adolescent; Anemia, Hemolytic; Chloroquine; Drug Hypersensitivity; Edema; Erythrocytes; Glucosephosp | 1970 |
Quinoline antimalarials. Folded chloroquine.
Topics: Animals; Antimalarials; Carrageenan; Chloroquine; Edema; Hydroxychloroquine; Mice; Piperidines; Quin | 1969 |
Ocular changes in swine associated with chloroquine toxicity.
Topics: Animals; Chloroquine; Choroid; Cytoplasmic Granules; Edema; Eosinophils; Eye Diseases; Fundus Oculi; | 1969 |
Evans blue-carrageenan pleural effusion as a model for the assay of nonsteroidal antirheumatic drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carrageenan; Chloroquine; Coloring Agents; Ed | 1969 |