chloroquine has been researched along with Disseminated Intravascular Coagulation in 9 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Disseminated Intravascular Coagulation: A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The exact treatment of sepsis is still the subject of considerable debate." | 2.58 | Sepsis: The Involvement of Platelets and the Current Treatments. ( Ganaes, JOF; Lopes-Pires, ME; Naime, ACA, 2018) |
| "Patients showed no signs of overt disseminated intravascular coagulation (DIC) in their laboratory analysis." | 1.56 | Severe arterial thromboembolism in patients with Covid-19. ( Buise, MP; Canta, LR; Hendriks, J; Krietemeijer, GM; Lameijer, JRC; Nijziel, MR; Troquay, SAM; van Berckel, MMG; van Houte, J; Yo, LSF, 2020) |
| "Laboratory investigation indicated disseminated intravascular coagulation confirmed by petechial hemorrhages in the leptomeninges at autopsy, a finding that has not previously been described." | 1.29 | Suicidal chloroquine poisoning: clinical course, autopsy findings, and chemical analysis. ( Bauer, G; Berzlanovich, A; Binder, R; Laggner, AN; Malzer, R; Mortinger, H; Muhm, M; Stimpfl, T; Vycudilik, W, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kang, Y | 1 |
| Chen, T | 1 |
| Mui, D | 1 |
| Ferrari, V | 1 |
| Jagasia, D | 1 |
| Scherrer-Crosbie, M | 1 |
| Chen, Y | 1 |
| Han, Y | 1 |
| Oscanoa, TJ | 1 |
| Romero-Ortuno, R | 1 |
| Carvajal, A | 1 |
| Savarino, A | 1 |
| Lameijer, JRC | 1 |
| van Houte, J | 1 |
| van Berckel, MMG | 1 |
| Canta, LR | 1 |
| Yo, LSF | 1 |
| Nijziel, MR | 1 |
| Krietemeijer, GM | 1 |
| Troquay, SAM | 1 |
| Buise, MP | 1 |
| Hendriks, J | 1 |
| Naime, ACA | 1 |
| Ganaes, JOF | 1 |
| Lopes-Pires, ME | 1 |
| Muhm, M | 1 |
| Stimpfl, T | 1 |
| Malzer, R | 1 |
| Mortinger, H | 1 |
| Binder, R | 1 |
| Vycudilik, W | 1 |
| Berzlanovich, A | 1 |
| Bauer, G | 1 |
| Laggner, AN | 1 |
| Reid, HA | 1 |
| Nkrumah, FK | 1 |
| Gyr, K | 1 |
| Speck, B | 1 |
| Ritz, R | 1 |
| Cornu, P | 1 |
| Buckner, CD | 1 |
| Eales, L | 1 |
| Conte, J | 1 |
| Durand, D | 1 |
| Ton That, H | 1 |
| Suc, JM | 1 |
3 reviews available for chloroquine and Disseminated Intravascular Coagulation
| Article | Year |
|---|---|
Cardiovascular manifestations and treatment considerations in COVID-19.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inh | 2020 |
A pharmacological perspective of chloroquine in SARS-CoV-2 infection: An old drug for the fight against a new coronavirus?
Topics: Angiotensin-Converting Enzyme 2; Anti-Inflammatory Agents; Anticoagulants; Antiviral Agents; Autopha | 2020 |
Sepsis: The Involvement of Platelets and the Current Treatments.
Topics: Acetylcysteine; Animals; Blood Platelets; Capsaicin; Chloroquine; Disseminated Intravascular Coagula | 2018 |
6 other studies available for chloroquine and Disseminated Intravascular Coagulation
| Article | Year |
|---|---|
Severe arterial thromboembolism in patients with Covid-19.
Topics: Aged, 80 and over; Blood Coagulation; Blood Coagulation Disorders; Chloroquine; COVID-19; COVID-19 D | 2020 |
Suicidal chloroquine poisoning: clinical course, autopsy findings, and chemical analysis.
Topics: Adolescent; Brain; Chloroquine; Disseminated Intravascular Coagulation; Fatal Outcome; Female; Foren | 1996 |
Fibrin-degradation products in cerebral malaria.
Topics: Adolescent; Adult; Blood Coagulation Tests; Blood Platelets; Cerebrovascular Disorders; Child, Presc | 1972 |
[Cerebral tropical malaria with blackwater fever. A current diagnostic and therapeutic problem].
Topics: Acute Kidney Injury; Adult; Blackwater Fever; Brain Diseases; Chloroquine; Disseminated Intravascula | 1974 |
Acute falciparum malaria. Complications and treatment.
Topics: Acute Kidney Injury; Brain Diseases; Chloroquine; Coma; Disseminated Intravascular Coagulation; Hepa | 1974 |
[Acute kidney failure and hemolytic anemia caused by erythrocytic G6PD dificit revealed by chloroquine administration].
Topics: Acute Kidney Injury; Anemia, Hemolytic; Chloroquine; Disseminated Intravascular Coagulation; Female; | 1973 |