chloroquine has been researched along with Dermatitis, Atopic in 6 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Atopic dermatitis is often associated with increased pain." | 1.91 | Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis. ( Akiyama, T; Bystrom, L; Ishida, H; Markan, A; Pavlenko, D; Todurga Seven, Z; Verpile, R, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Pavlenko, D | 1 |
| Todurga Seven, Z | 1 |
| Bystrom, L | 1 |
| Markan, A | 1 |
| Verpile, R | 1 |
| Ishida, H | 1 |
| Akiyama, T | 1 |
| Ramachandran, R | 1 |
| Thompson, SK | 1 |
| Malkmus, S | 1 |
| Mieda, T | 1 |
| Lin, JH | 1 |
| Gupta, S | 1 |
| Yaksh, TL | 1 |
| SIDI, E | 1 |
| REINBERG, A | 1 |
| HINCKY, M | 1 |
| MAKARENKO, II | 1 |
| LEVITSKII, ER | 1 |
| Zirwas, MJ | 1 |
| Döring, HF | 1 |
| Müllejans-Kreppel, U | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 1, Randomized, Double-Blind, Vehicle-Controlled Ascending Doses Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ASN008 Topical Gel in Healthy Volunteers and Subjects With Atopic Dermatitis[NCT03798561] | Phase 1 | 24 participants (Actual) | Interventional | 2019-01-14 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for chloroquine and Dermatitis, Atopic
| Article | Year |
|---|---|
Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis.
Topics: Animals; Calcium; Capsaicin; Chloroquine; Dermatitis, Atopic; Disease Models, Animal; Histamine; Neu | 2023 |
Topical Application of ASN008, a Permanently Charged Sodium Channel Blocker, Shows Robust Efficacy, a Rapid Onset, and Long Duration of Action in a Mouse Model of Pruritus.
Topics: Administration, Topical; Animals; Antipruritics; Chloroquine; Dermatitis, Atopic; Disease Models, An | 2020 |
[Treatment of cutaneous allergy with synthetic antimalarials (chronic obstinate urticaria)].
Topics: Antimalarials; Chloroquine; Chronic Disease; Dermatitis, Atopic; Humans; Urticaria | 1961 |
[RESOCHIN IN CLINICAL INTERNAL MEDICINE AND ITS POSSIBLE SIDE EFFECTS].
Topics: Acute Kidney Injury; Antimalarials; Arthritis; Arthritis, Rheumatoid; Chloroquine; Collagen Diseases | 1964 |
Dramatic response to chloroquine and mirtazapine for recalcitrant atopic dermatitis.
Topics: Adolescent; Antimalarials; Chloroquine; Dermatitis, Atopic; Drug Therapy, Combination; Histamine H1 | 2006 |
[Chloroquine--therapy of atopic dermatitis].
Topics: Adolescent; Adult; Aged; Chloroquine; Dermatitis, Atopic; Dose-Response Relationship, Drug; Drug Adm | 1987 |