chloroquine has been researched along with Dementia Praecox in 6 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine has been known to be a potent inhibitor of house-keeping GDH1 in permeabilized liver and kidney-cortex of rabbit." | 1.34 | Inhibitory properties of nerve-specific human glutamate dehydrogenase isozyme by chloroquine. ( Cho, SW; Choi, MM; Choi, SY; Kim, EA; Kim, TU; Yang, SJ, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kwak, YT | 1 |
| Yang, Y | 1 |
| Park, SY | 1 |
| YVONNEAU, M | 1 |
| FELDMAN, N | 1 |
| Choi, MM | 1 |
| Kim, EA | 1 |
| Choi, SY | 1 |
| Kim, TU | 1 |
| Cho, SW | 1 |
| Yang, SJ | 1 |
| Traficante, LJ | 1 |
| Hine, B | 1 |
| Gershon, S | 1 |
| Sakalis, G | 1 |
| Flayeh, KA | 1 |
| Makanjuola, RO | 1 |
| Dixon, PA | 1 |
| Oforah, E | 1 |
2 trials available for chloroquine and Dementia Praecox
| Article | Year |
|---|---|
Chloroquine potentiation of thioridazine effects in rats and drug-resistant schizophrenic patients: a preliminary report.
Topics: Amphetamine; Animals; Brain; Chloroquine; Clinical Trials as Topic; Drug Resistance; Drug Synergism; | 1977 |
Effects of antimalarial agents on plasma levels of chlorpromazine and its metabolites in schizophrenic patients.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Chloroquine; Chlorpromazine; Drug Combinations; Drug | 1988 |
4 other studies available for chloroquine and Dementia Praecox
| Article | Year |
|---|---|
Chloroquine-associated psychosis mimicking very late-onset schizophrenia: Case Report.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Diagnosis, Differential; Dose-Respon | 2015 |
[PSYCHOTROPIC EFFECTS OF A SYNTHETIC ANTIMALARIAL].
Topics: Antimalarials; Chloroquine; Dementia; Depressive Disorder, Major; Drug Therapy; Gentisates; Geriatri | 1965 |
Inhibitory properties of nerve-specific human glutamate dehydrogenase isozyme by chloroquine.
Topics: Allosteric Regulation; Central Nervous System; Chloroquine; Enzyme Inhibitors; Escherichia coli; Glu | 2007 |
Spermidine oxidase activity in serum of normal and schizophrenic subjects.
Topics: Adult; Chloroquine; Female; Humans; Male; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; | 1988 |