chloroquine has been researched along with Degenerative Disc Disease in 4 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, S | 1 |
| Chen, L | 1 |
| Al Mamun, A | 1 |
| Ni, L | 1 |
| Gao, W | 2 |
| Lin, Y | 1 |
| Jin, H | 1 |
| Zhang, X | 2 |
| Wang, X | 2 |
| Zheng, G | 1 |
| Pan, Z | 1 |
| Zhan, Y | 1 |
| Tang, Q | 1 |
| Zheng, F | 1 |
| Zhou, Y | 3 |
| Wu, Y | 1 |
| Chen, D | 1 |
| Chen, J | 1 |
| Xu, H | 1 |
| Tian, N | 1 |
| Zuo, R | 1 |
| Wang, Y | 1 |
| Li, J | 1 |
| Wu, J | 1 |
| Wang, W | 1 |
| Li, B | 1 |
| Sun, C | 1 |
| Wang, Z | 1 |
| Shi, C | 1 |
| Liu, M | 1 |
| Zhang, C | 1 |
| Ma, KG | 1 |
| Shao, ZW | 1 |
| Yang, SH | 1 |
| Wang, J | 1 |
| Wang, BC | 1 |
| Xiong, LM | 1 |
| Wu, Q | 1 |
| Chen, SF | 1 |
4 other studies available for chloroquine and Degenerative Disc Disease
| Article | Year |
|---|---|
The therapeutic effect of TBK1 in intervertebral disc degeneration via coordinating selective autophagy and autophagic functions.
Topics: Animals; Apoptosis; Autophagy; Cellular Senescence; Chloroquine; Humans; Intervertebral Disc Degener | 2021 |
TFEB protects nucleus pulposus cells against apoptosis and senescence via restoring autophagic flux.
Topics: Animals; Apoptosis; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cells, C | 2019 |
Rapamycin Induced Autophagy Inhibits Inflammation-Mediated Endplate Degeneration by Enhancing Nrf2/Keap1 Signaling of Cartilage Endplate Stem Cells.
Topics: Animals; Autophagy; Cartilage; Cell Differentiation; Chloroquine; Chondrogenesis; Disease Models, An | 2019 |
Autophagy is activated in compression-induced cell degeneration and is mediated by reactive oxygen species in nucleus pulposus cells exposed to compression.
Topics: Adenine; Animals; Apoptosis; Autophagy; Blotting, Western; Cells, Cultured; Chloroquine; Immunohisto | 2013 |