chloroquine has been researched along with Cystic Fibrosis of Pancreas in 9 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vasculitis is a well recognised complication of Cystic Fibrosis." | 5.36 | Treatment of cystic fibrosis associated cutaneous vasculitis with chloroquine. ( Molyneux, ID; Moon, T; Morice, AH; Webb, AK, 2010) |
| "Transforming growth factor beta (TGF-beta) has been implicated in pathophysiology of CF." | 5.33 | Chloroquine normalizes aberrant transforming growth factor beta activity in cystic fibrosis bronchial epithelial cells. ( Deretic, V; Ornatowski, W; Perkett, EA; Poschet, JF, 2006) |
| "Vasculitis is a well recognised complication of Cystic Fibrosis." | 1.36 | Treatment of cystic fibrosis associated cutaneous vasculitis with chloroquine. ( Molyneux, ID; Moon, T; Morice, AH; Webb, AK, 2010) |
| "Transforming growth factor beta (TGF-beta) has been implicated in pathophysiology of CF." | 1.33 | Chloroquine normalizes aberrant transforming growth factor beta activity in cystic fibrosis bronchial epithelial cells. ( Deretic, V; Ornatowski, W; Perkett, EA; Poschet, JF, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Pohl, K | 1 |
| Grimm, XA | 1 |
| Caceres, SM | 1 |
| Poch, KR | 1 |
| Rysavy, N | 1 |
| Saavedra, M | 1 |
| Nick, JA | 1 |
| Malcolm, KC | 1 |
| Molyneux, ID | 1 |
| Moon, T | 1 |
| Webb, AK | 1 |
| Morice, AH | 1 |
| Derleth, DP | 1 |
| Perkett, EA | 1 |
| Ornatowski, W | 1 |
| Poschet, JF | 1 |
| Deretic, V | 1 |
| Kollen, WJ | 2 |
| Midoux, P | 1 |
| Erbacher, P | 1 |
| Yip, A | 1 |
| Roche, AC | 1 |
| Monsigny, M | 1 |
| Glick, MC | 3 |
| Scanlin, TF | 3 |
| Schembri, FM | 1 |
| Gerwig, GJ | 1 |
| Vliegenthart, JF | 1 |
| Gibson, GA | 1 |
| Hill, WG | 1 |
| Weisz, OA | 1 |
| Klink, DT | 1 |
| Chao, S | 1 |
| Hermelin, B | 1 |
| Bertrand, F | 1 |
| Blivet, MJ | 1 |
| Picard, J | 1 |
9 other studies available for chloroquine and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Mycobacterium abscessus Clearance by Neutrophils Is Independent of Autophagy.
Topics: Adaptor Proteins, Signal Transducing; Anti-Bacterial Agents; Autophagy; Azithromycin; Case-Control S | 2020 |
Treatment of cystic fibrosis associated cutaneous vasculitis with chloroquine.
Topics: Adult; Antirheumatic Agents; Chloroquine; Cystic Fibrosis; Exanthema; Humans; Male; Skin; Vasculitis | 2010 |
A possible antiinflammatory treatment for cystic fibrosis.
Topics: Chloroquine; Clinical Trials as Topic; Cystic Fibrosis; Female; Humans; Male; Research; Sensitivity | 2003 |
Chloroquine normalizes aberrant transforming growth factor beta activity in cystic fibrosis bronchial epithelial cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Cells, Cultured; Chloroquine; Culture Media, Condi | 2006 |
Gluconoylated and glycosylated polylysines as vectors for gene transfer into cystic fibrosis airway epithelial cells.
Topics: Cell Count; Cells, Cultured; Chloroquine; Cystic Fibrosis; Epithelium; Gene Expression; Gene Transfe | 1996 |
Enhanced efficiency of lactosylated poly-L-lysine-mediated gene transfer into cystic fibrosis airway epithelial cells.
Topics: Amino Acid Sequence; Cell Line, Transformed; Chloroquine; Cystic Fibrosis; Gene Expression Regulatio | 1999 |
Evidence against the acidification hypothesis in cystic fibrosis.
Topics: Acids; Adenocarcinoma; Adenoviridae; Animals; Biological Transport; Cell Compartmentation; Cell Line | 2000 |
Nuclear translocation of lactosylated poly-L-lysine/cDNA complex in cystic fibrosis airway epithelial cells.
Topics: Cell Line, Transformed; Cell Nucleus; Chloroquine; Cystic Fibrosis; DNA, Complementary; Epithelial C | 2001 |
Change in activities of lysosomal glycosidases in skin fibroblasts from controls and patients with cystic fibrosis.
Topics: alpha-L-Fucosidase; alpha-Mannosidase; beta-N-Acetylhexosaminidases; Chloroquine; Culture Media; Cys | 1987 |