chloroquine has been researched along with Cryptococcosis in 8 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Cryptococcosis: Fungal infection caused by genus CRYPTOCOCCUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluconazole alone was not found significantly effective against C." | 5.32 | Prophylactic role of liposomized chloroquine against murine cryptococcosis less susceptible to fluconazole. ( Jabeen, R; Khan, MA; Mohammad, O, 2004) |
| "Fluconazole alone was not found significantly effective against C." | 1.32 | Prophylactic role of liposomized chloroquine against murine cryptococcosis less susceptible to fluconazole. ( Jabeen, R; Khan, MA; Mohammad, O, 2004) |
| "Chloroquine (CQ) is a weak base that accumulates within acidic vacuoles and increases their pH." | 1.30 | Enhanced resistance to Cryptococcus neoformans infection induced by chloroquine in a murine model of meningoencephalitis. ( Barluzzi, R; Bistoni, F; Blasi, E; Boelaert, JR; Brozzetti, A; Luna, T; Mazzolla, R; Saleppico, S, 1997) |
| "Ammonium chloride was also beneficial, suggesting that effects were mediated by alkalinizing the phagolysosome." | 1.30 | Chloroquine induces human mononuclear phagocytes to inhibit and kill Cryptococcus neoformans by a mechanism independent of iron deprivation. ( Harrison, TS; Levitz, SM; Liu, X; Tabuni, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, MA | 2 |
| Jabeen, R | 2 |
| Nasti, TH | 1 |
| Mohammad, O | 2 |
| Ma, H | 1 |
| Croudace, JE | 1 |
| Lammas, DA | 1 |
| May, RC | 1 |
| Blasi, E | 3 |
| Barluzzi, R | 3 |
| Mazzolla, R | 3 |
| Bistoni, F | 3 |
| Brozzetti, A | 1 |
| Boelaert, JR | 1 |
| Luna, T | 1 |
| Saleppico, S | 1 |
| Levitz, SM | 2 |
| Harrison, TS | 2 |
| Tabuni, A | 1 |
| Liu, X | 1 |
| Weber, SM | 1 |
| Mosci, P | 1 |
1 review available for chloroquine and Cryptococcosis
| Article | Year |
|---|---|
Chloroquine and the fungal phagosome.
Topics: Animals; Antifungal Agents; Chloroquine; Cryptococcosis; Cryptococcus neoformans; Histoplasma; Histo | 2000 |
7 other studies available for chloroquine and Cryptococcosis
| Article | Year |
|---|---|
Enhanced anticryptococcal activity of chloroquine in phosphatidylserine-containing liposomes in a murine model.
Topics: Animals; Cell Line; Chloroquine; Cryptococcosis; Cryptococcus neoformans; Disease Models, Animal; Dr | 2005 |
Prophylactic role of liposomized chloroquine against murine cryptococcosis less susceptible to fluconazole.
Topics: Animals; Cell Line; Chloroquine; Cryptococcosis; Cryptococcus neoformans; Disease Models, Animal; Di | 2004 |
Expulsion of live pathogenic yeast by macrophages.
Topics: Animals; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chloroquine; Cryptococcosis; Cryp | 2006 |
Differential host susceptibility to intracerebral infections with Candida albicans and Cryptococcus neoformans.
Topics: Animals; Brain Diseases; Candidiasis; Chloroquine; Colchicine; Cryptococcosis; Disease Susceptibilit | 1993 |
Enhanced resistance to Cryptococcus neoformans infection induced by chloroquine in a murine model of meningoencephalitis.
Topics: Animals; Antifungal Agents; Brain; Cell Line; Chloroquine; Cryptococcosis; Cytokines; Female; Lysoso | 1997 |
Chloroquine induces human mononuclear phagocytes to inhibit and kill Cryptococcus neoformans by a mechanism independent of iron deprivation.
Topics: Ammonium Chloride; Animals; Antifungal Agents; Apoproteins; Chloroquine; Cryptococcosis; Cryptococcu | 1997 |
Experimental model of intracerebral infection with Cryptococcus neoformans: roles of phagocytes and opsonization.
Topics: Animals; Brain Diseases; Chloroquine; Colchicine; Cryptococcosis; Disease Models, Animal; Female; Mi | 1992 |