chloroquine has been researched along with Coronary Disease in 6 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine is known to inhibit platelet activation by various mechanisms including arachidonic acid liberation from membrane phospholipids." | 1.30 | Chloroquine minimizes sampling artefacts for radioimmunological determination of thromboxane B2 in plasma. ( al-Malicky, B; Kritz, H; Oguogho, A; Sinzinger, H, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| El Boussadani, B | 1 |
| Benajiba, C | 1 |
| Aajal, A | 1 |
| Ait Brik, A | 1 |
| Ammour, O | 1 |
| El Hangouch, J | 1 |
| Oussama, O | 1 |
| Oussama, B | 1 |
| Tahiri, N | 1 |
| Raissuni, Z | 1 |
| Wildenthal, K | 1 |
| Decker, RS | 1 |
| Oguogho, A | 1 |
| al-Malicky, B | 1 |
| Kritz, H | 1 |
| Sinzinger, H | 1 |
| Friedman, G | 1 |
| Stein, O | 1 |
| Halperin, G | 1 |
| Kimchi, A | 1 |
| Stein, Y | 1 |
| Karmazyn, M | 1 |
| Horrobin, DF | 1 |
| Oka, M | 1 |
| Manku, MS | 1 |
| Ally, AI | 1 |
| Karmali, RA | 1 |
| Morgan, RO | 1 |
| Cunnane, SC | 1 |
| Fazekas, T | 1 |
| Szekeres, L | 1 |
1 review available for chloroquine and Coronary Disease
| Article | Year |
|---|---|
[COVID-19 pandemia: Impact on the cariovascular system. Data of 1
Topics: Antimalarials; Antiviral Agents; Azithromycin; Betacoronavirus; Cardiomyopathies; Cardiovascular Dis | 2020 |
5 other studies available for chloroquine and Coronary Disease
| Article | Year |
|---|---|
The role of lysosomes in the heart.
Topics: Animals; Chloroquine; Coronary Disease; Heart; Humans; Lysosomes; Metabolism; Mice; Myocardium; Prot | 1980 |
Chloroquine minimizes sampling artefacts for radioimmunological determination of thromboxane B2 in plasma.
Topics: Adult; Aged; Artifacts; Chloroquine; Coronary Disease; Female; Humans; Male; Middle Aged; Peripheral | 1997 |
Study of cultured skin fibroblasts from patients with and without ischemic heart disease. Metabolism of low density lipoprotein and cholesterol ester, synthesis of cellular lipids and effect of chloroquine on accumulation of cholesterol ester.
Topics: Adult; Cells, Cultured; Chloroquine; Cholesterol; Cholesterol Esters; Coronary Disease; Fibroblasts; | 1978 |
Changes in coronary vascular resistance associated with prolonged hypoxia in isolated rat hearts: a possible role of prostaglandins.
Topics: Aging; Animals; Aspirin; Chloroquine; Coronary Circulation; Coronary Disease; In Vitro Techniques; I | 1979 |
Effect of chloroquine in experimental myocardial ischaemia.
Topics: Animals; Blood Pressure; Chloroquine; Coronary Disease; Dogs; Fatty Acids, Nonesterified; Heart; Mal | 1988 |