chloroquine has been researched along with Corneal Diseases in 25 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Corneal Diseases: Diseases of the cornea.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-six eyes of 36 patients with rheumatoid arthritis (RA) were divided into two groups: group 1 included 26 patients receiving chloroquine therapy; group 2 included the other 10 patients, not receiving chloroquine therapy." | 7.78 | Chloroquine keratopathy of rheumatoid arthritis patients detected by in vivo confocal microscopy. ( He, D; He, L; Ma, X; Xu, J, 2012) |
| "Thirty-six eyes of 36 patients with rheumatoid arthritis (RA) were divided into two groups: group 1 included 26 patients receiving chloroquine therapy; group 2 included the other 10 patients, not receiving chloroquine therapy." | 3.78 | Chloroquine keratopathy of rheumatoid arthritis patients detected by in vivo confocal microscopy. ( He, D; He, L; Ma, X; Xu, J, 2012) |
| "Antimalarial drugs including chloroquine, its less toxic quinolone-derivative hydroxychloroquine (HCQ), and quinacrine have become cornerstones in the treatment of autoimmune diseases including systemic lupus, rheumatoid arthritis, sarcoidosis, and Sjogren syndrome; cutaneous disorders, antiphospholipid syndrome, and have recently been employed at higher dioses in oncology." | 2.58 | Hydroxychloroquine: balancing the need to maintain therapeutic levels with ocular safety: an update. ( Abdulaziz, N; McCune, WJ; Shah, AR, 2018) |
| "We reviewed the most recent systemic drugs used in Belgium causing toxic corneal side effects." | 2.44 | [Toxic effects of medications on the cornea]. ( Ravet, O, 2007) |
| "Cumulative drug dosage, Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), and Systemic Lupus Erythematosus International Collaborating Clinics/American College of Rheumatology damage index (SLICC/ACR-DI) scores were calculated." | 1.51 | Corneal vortex keratopathy in childhood-onset systemic lupus erythematosus (c-SLE). ( Appenzeller, S; Carneiro, P; Paim-Marques, L; Verçosa, IC, 2019) |
| "Mean intraocular pressure was 12 mmHg (standard deviation, 4." | 1.35 | Ocular manifestation in treated multibacillary Hansen's disease. ( Muliyil, J; Parikh, R; Parikh, S; Thomas, R; Thomas, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (72.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdulaziz, N | 1 |
| Shah, AR | 1 |
| McCune, WJ | 1 |
| Paim-Marques, L | 1 |
| Carneiro, P | 1 |
| Verçosa, IC | 1 |
| Appenzeller, S | 1 |
| Parikh, R | 1 |
| Thomas, S | 1 |
| Muliyil, J | 1 |
| Parikh, S | 1 |
| Thomas, R | 1 |
| Ma, X | 1 |
| He, L | 1 |
| He, D | 1 |
| Xu, J | 1 |
| ZELLER, RW | 1 |
| DEERING, D | 1 |
| BERNSTEIN, SI | 1 |
| KALISH, B | 1 |
| CHAVANNE, H | 1 |
| JEANTET, R | 1 |
| DEMILLIERE, B | 1 |
| HERTZBERG, R | 1 |
| JUNEMANN, C | 1 |
| VERDAGUER, J | 1 |
| PERALES, J | 1 |
| LIRA, C | 1 |
| DOMINGUEZ, JP | 1 |
| OROZCO, R | 1 |
| Ravet, O | 1 |
| Hobbs, HE | 1 |
| Eadie, SP | 1 |
| Somerville, F | 1 |
| Pilger, IS | 1 |
| Drenckhahn, D | 1 |
| Jacobi, B | 1 |
| Lüllmann-Rauch, R | 1 |
| Lanham, JG | 1 |
| Hughes, GR | 1 |
| D'Amico, DJ | 1 |
| Kenyon, KR | 1 |
| Jeddi, A | 1 |
| Ben Osman, N | 1 |
| Daghfous, F | 1 |
| Bouguila, H | 1 |
| Charfi, O | 1 |
| Ayed, S | 1 |
| Easterbrook, M | 2 |
| Seiler, KU | 1 |
| Thiel, HJ | 2 |
| Wassermann, O | 1 |
| Pülhorn, G | 1 |
| Eriksen, LS | 1 |
| Crews, SJ | 1 |
| Lozier, JR | 1 |
| Friedlaender, MH | 1 |
| George, JL | 1 |
| Cullen, AP | 1 |
| Chou, BR | 1 |
4 reviews available for chloroquine and Corneal Diseases
| Article | Year |
|---|---|
Hydroxychloroquine: balancing the need to maintain therapeutic levels with ocular safety: an update.
Topics: Antirheumatic Agents; Chloroquine; Corneal Diseases; Dose-Response Relationship, Drug; Drug Administ | 2018 |
[Toxic effects of medications on the cornea].
Topics: Belgium; Chloroquine; Cornea; Corneal Diseases; Cytarabine; Drug-Related Side Effects and Adverse Re | 2007 |
Antimalarial therapy in SLE.
Topics: Antimalarials; Binding Sites; Chloroquine; Corneal Diseases; Dose-Response Relationship, Drug; Femal | 1982 |
Complications of antimalarial therapy.
Topics: Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Ciliary Body; Color Perception; Corneal D | 1989 |
21 other studies available for chloroquine and Corneal Diseases
| Article | Year |
|---|---|
Corneal vortex keratopathy in childhood-onset systemic lupus erythematosus (c-SLE).
Topics: Adolescent; Age of Onset; Child; Chloroquine; Comorbidity; Corneal Diseases; Female; Follow-Up Studi | 2019 |
Ocular manifestation in treated multibacillary Hansen's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blindness; Cataract; Child; Chloroquine; Corneal Disease | 2009 |
Chloroquine keratopathy of rheumatoid arthritis patients detected by in vivo confocal microscopy.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; China; Chloroquine; Cornea; Corneal Diseas | 2012 |
Corneal complication of chloroquine (aralen) phosphate therapy.
Topics: Chloroquine; Cornea; Corneal Diseases; Disease; Humans; Phosphates | 1958 |
Chloroquine keratopathy.
Topics: Chloroquine; Cornea; Corneal Diseases; Humans | 1963 |
[KERATOPATHY IN WORKERS ENGAGED IN THE MANUFACTURE OF CHLOROQUINE].
Topics: Chloroquine; Cornea; Corneal Diseases; Eye Diseases; Humans; Occupational Diseases; Toxicology | 1964 |
Corneal oedema due to "chloroquine".
Topics: Chloroquine; Cornea; Corneal Diseases; Corneal Edema; Disease; Edema; Humans | 1960 |
[Corneal lesions associated with the administration of chloroquine and other antimalarials].
Topics: Antimalarials; Chloroquine; Cornea; Corneal Diseases; Humans | 1962 |
OCULAR LESIONS AFTER TREATMENT WITH CHLOROQUINE.
Topics: Antimalarials; Chloroquine; Corneal Diseases; Eye; Humans | 1961 |
Pigmentation of the cornea: a review and classification.
Topics: Adult; Child; Chloroquine; Chlorpromazine; Corneal Diseases; Drug-Related Side Effects and Adverse R | 1983 |
Corneal lipidosis in rats treated with amphiphilic cationic drugs.
Topics: Animals; Cations; Chloroquine; Chlorphentermine; Corneal Diseases; Female; Iprindole; Lipidoses; Mal | 1983 |
Drug-induced lipidoses of the cornea and conjunctiva.
Topics: Amiodarone; Amodiaquine; Chloroquine; Conjunctival Diseases; Corneal Diseases; Fabry Disease; Female | 1981 |
[The cornea and synthetic antimalarials].
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Corneal Diseases; Female; Humans; Male; Middle Aged; | 1994 |
Screening for antimalarial toxicity.
Topics: Chloroquine; Color Perception Tests; Corneal Diseases; Humans; Hydroxychloroquine; Retinal Diseases; | 1993 |
[Chloroquine keratopathy as an example of drug-induced phospholipidosis (contribution to the pathogenesis of cornea verticillata) (author's transl)].
Topics: Adrenal Glands; Animals; Chloroquine; Chlorphentermine; Corneal Diseases; Cytoplasm; Hydrogen-Ion Co | 1977 |
[Ultrastructural aspects of chloroquin-keratopathy (author's transl)].
Topics: Chloroquine; Cornea; Corneal Diseases; Epithelium; Humans; Inclusion Bodies; Lipidoses; Microscopy, | 1976 |
Chloroquine keratopathy in chloroquine workers after topical dust exponation. A case report.
Topics: Chloroquine; Cornea; Corneal Diseases; Drug Industry; Dust; Humans; Male; Middle Aged; Occupational | 1979 |
Ocular adverse reactions to drugs.
Topics: Adrenal Cortex Hormones; Adult; Aged; Amblyopia; Cataract; Chloroquine; Chlorpromazine; Conjunctivit | 1977 |
[Corneal, conjunctival and lacrimal changes (excluding dry eye)].
Topics: Adrenal Cortex Hormones; Amiodarone; Anesthetics, Local; Anti-Bacterial Agents; Antineoplastic Agent | 1985 |
Ocular effects and safety of antimalarial agents.
Topics: Antimalarials; Chloroquine; Corneal Diseases; Drug Administration Schedule; Electrooculography; Elec | 1988 |
Keratopathy with low dose chloroquine therapy.
Topics: Adult; Aged; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; Chloroquine; Corneal Diseases; Fe | 1986 |