chloroquine has been researched along with Cognition Disorders in 3 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human cerebral malaria causes neurological and behavioral deficits which persist long after resolution of infection and clearance of parasites with antimalarial drugs." | 1.36 | Persistent cognitive and motor deficits after successful antimalarial treatment in murine cerebral malaria. ( Dai, M; Desruisseaux, MS; Gulinello, M; Reznik, SE; Spray, DC; Tanowitz, HB; Weiss, LM, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, J | 1 |
| Zhang, X | 1 |
| Yu, M | 1 |
| Ren, G | 1 |
| Yang, Z | 1 |
| Dai, M | 1 |
| Reznik, SE | 1 |
| Spray, DC | 1 |
| Weiss, LM | 1 |
| Tanowitz, HB | 1 |
| Gulinello, M | 1 |
| Desruisseaux, MS | 1 |
| Reis, PA | 1 |
| Estato, V | 1 |
| da Silva, TI | 1 |
| d'Avila, JC | 1 |
| Siqueira, LD | 1 |
| Assis, EF | 1 |
| Bozza, PT | 1 |
| Bozza, FA | 1 |
| Tibiriça, EV | 1 |
| Zimmerman, GA | 1 |
| Castro-Faria-Neto, HC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Early Atorvastatin Treatment During the Acute Phase of Stroke on Immunoinflammatory Markers and Outcome in Patients With Acute Ischemic Stroke Classified as LAAS According TOAST Classification[NCT02225834] | Phase 4 | 50 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for chloroquine and Cognition Disorders
| Article | Year |
|---|---|
Cognitive deficits induced by multi-walled carbon nanotubes via the autophagic pathway.
Topics: Animals; Autophagy; Body Weight; CA1 Region, Hippocampal; Chloroquine; Cognition Disorders; Long-Ter | 2015 |
Persistent cognitive and motor deficits after successful antimalarial treatment in murine cerebral malaria.
Topics: Animals; Antimalarials; Chloroquine; Cognition Disorders; Disease Models, Animal; Female; Malaria, C | 2010 |
Statins decrease neuroinflammation and prevent cognitive impairment after cerebral malaria.
Topics: Animals; Brain; CD11b Antigen; Chemokines; Chloroquine; Cognition Disorders; Cytokines; Edema; Endot | 2012 |