chloroquine has been researched along with Clinically Isolated CNS Demyelinating Syndrome in 4 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During SC dedifferentiation-associated demyelination (SAD) in Wallerian degeneration (WD) after axonal injury, SCs exhibit myelin and junctional instability, down-regulation of myelin gene expression and autophagic myelin breakdown." | 1.46 | Schwann cell dedifferentiation-associated demyelination leads to exocytotic myelin clearance in inflammatory segmental demyelination. ( Ahn, M; Choi, YY; Jang, SY; Jo, YR; Kim, JK; Park, HT; Park, JI; Shin, T; Shin, YK; Yoon, BA; Yun, SH, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jang, SY | 1 |
| Yoon, BA | 1 |
| Shin, YK | 1 |
| Yun, SH | 1 |
| Jo, YR | 1 |
| Choi, YY | 1 |
| Ahn, M | 1 |
| Shin, T | 1 |
| Park, JI | 1 |
| Kim, JK | 1 |
| Park, HT | 1 |
| Smith, CM | 1 |
| Mayer, JA | 1 |
| Duncan, ID | 1 |
| Tegnér, R | 1 |
| Tomé, FM | 1 |
| Godeau, P | 1 |
| Lhermitte, F | 1 |
| Fardeau, M | 1 |
| DeVivo, DC | 1 |
| Engel, WK | 1 |
4 other studies available for chloroquine and Clinically Isolated CNS Demyelinating Syndrome
| Article | Year |
|---|---|
Schwann cell dedifferentiation-associated demyelination leads to exocytotic myelin clearance in inflammatory segmental demyelination.
Topics: Animals; Autophagy-Related Protein 7; Axotomy; Cell Dedifferentiation; Chloroquine; Demyelinating Di | 2017 |
Autophagy promotes oligodendrocyte survival and function following dysmyelination in a long-lived myelin mutant.
Topics: Age Factors; Animals; Animals, Newborn; Autophagy; Bromodeoxyuridine; Cell Survival; Cells, Cultured | 2013 |
Morphological study of peripheral nerve changes induced by chloroquine treatment.
Topics: Adult; Biopsy; Chloroquine; Demyelinating Diseases; Female; Humans; Male; Middle Aged; Nerve Degener | 1988 |
Remarkable recovery of a steroid-responsive recurrent polyneuropathy.
Topics: Biopsy; Child; Chloroquine; Demyelinating Diseases; Electromyography; Female; Humans; Locomotion; Mu | 1970 |