chloroquine has been researched along with Chronic Disease in 107 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine (CQ) is an antimalarial drug that elicits severe pruritus in black Africans with malaria fever." | 9.01 | Itching, chloroquine, and malaria: a review of recent molecular and neuroscience advances and their contribution to mechanistic understanding and therapeutics of chronic non-histaminergic pruritus. ( Ajayi, AAL, 2019) |
| "Chloroquine (CQ) is an antimalarial drug that elicits severe pruritus in black Africans with malaria fever." | 5.01 | Itching, chloroquine, and malaria: a review of recent molecular and neuroscience advances and their contribution to mechanistic understanding and therapeutics of chronic non-histaminergic pruritus. ( Ajayi, AAL, 2019) |
| " An acetone-ether-water (AEW) model as a histamine-independent itch model is often used in the study of chronic pruritus." | 3.85 | MrgprA3 shows sensitization to chloroquine in an acetone-ether-water mice model. ( Geng, X; Gu, L; Hu, D; Lan, L; Shi, H; Tang, Z; Wang, C; Wu, G; Yang, N; Yang, Y; Yu, G; Yu, L; Yuan, X; Zhu, C, 2017) |
| " The children had persistent fever (5 or more days) despite treatment with chloroquine and were admitted to the Department of Child Health of the University of Ghana Medical School in Accra with severe malaria (Plasmodium falciparum)." | 3.69 | Persistent fever in severe malaria in children. ( Agyepong, I; Commey, J; Quarm-Goka, B, 1994) |
| "This suggested that 32 of the 47 recurrences were probable relapses of which 22 (69%) were genetically homologous." | 2.77 | Genotyping of Plasmodium vivax reveals both short and long latency relapse patterns in Kolkata. ( Addy, M; Day, NP; Dondorp, AM; Imwong, M; Kim, JR; Maji, AK; Nandy, A; Pukrittayakamee, S; White, NJ, 2012) |
| "A treatment with chloroquine is indicated in cases with contraindications again glucocorticoids and azathioprine." | 2.65 | [Therapy of chronic hepatitis (author's transl)]. ( Siede, W, 1979) |
| "The first line treatment of urticaria still consists of non-sedating H1-antihistamines." | 2.42 | [New therapeutic strategies for the different subtypes of urticaria]. ( Kapp, A; Liekenbröcker, T; Raap, U; Wedi, B; Wieczorek, D, 2004) |
| " Preliminary results seem to indicate, that the dosage used may be reduced slowly and therapy finally stopped after 3-4 years of treatment in most patients." | 2.36 | [Therapy of chronic hepatitis (author's transl)]. ( Arnold, W; Meyer zum Büschenfelde, KH, 1981) |
| "vivax malaria were randomized to receive chloroquine (CQ; 25 mg base/kg given over 3 days) alone or together with primaquine (PQ; 0." | 1.51 | Efficacy of Primaquine in Preventing Short- and Long-Latency Plasmodium vivax Relapses in Nepal. ( Adhikari, B; Banjara, MR; Chotivanich, K; Das Thakur, G; Day, NPJ; Ghimire, P; Hanboonkunupakarn, B; Imwong, M; Pukrittayakamee, S; Rijal, KR; White, NJ, 2019) |
| "Epigallocatechin gallate (EGCG) is a major polyphenol in green tea with beneficial effects on the impairment in learning and memory." | 1.40 | Epigallocatechin-3-gallate attenuates impairment of learning and memory in chronic unpredictable mild stress-treated rats by restoring hippocampal autophagic flux. ( Gu, HF; Jing, KQ; Liao, DF; Nie, YX; Tang, YL; Tong, QZ; Zeng, Y; Zheng, XL, 2014) |
| "The optimal treatment of Q fever endocarditis is still today debated, and recommended duration of treatment varies from one year to one's lifespan." | 1.31 | Doxycycline and chloroquine as treatment for chronic Q fever endocarditis. ( Attard, L; Calza, L; Chiodo, F; Manfredi, R, 2002) |
| "Chronic ulcerative stomatitis (CUS), a rare disease of oral mucosa found to be associated with unusual antinuclear antibodies reactive exclusively with squamous epithelia (squamous epithelium-specific antinuclear antibodies - SES-ANA), has been reported to occur almost exclusively in older females and to respond dramatically to antimalarials." | 1.30 | Is chronic ulcerative stomatitis an entity? Clinical and immunological findings in 18 cases. ( Chorzelski, TP; Jablonska, S; Jarzabek-Chorzelska, M; Olszewska, M, 1998) |
| "Pulmonary disease was the major manifestation in 70% and was present in 88%." | 1.27 | Longitudinal study of chronic sarcoidosis with low-dose maintenance corticosteroid therapy. Outcome and complications. ( Johns, CJ; MacGregor, MI; Schonfeld, SA; Scott, PP; Zachary, JB, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 76 (71.03) | 18.7374 |
| 1990's | 8 (7.48) | 18.2507 |
| 2000's | 10 (9.35) | 29.6817 |
| 2010's | 11 (10.28) | 24.3611 |
| 2020's | 2 (1.87) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, G | 1 |
| Wang, A | 1 |
| Wang, S | 3 |
| Qian, F | 1 |
| Chen, M | 1 |
| Yu, F | 1 |
| Zhang, J | 4 |
| Wang, X | 6 |
| Ma, X | 1 |
| Zhao, T | 2 |
| Zhang, F | 2 |
| Chen, Z | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 10 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Zhang, S | 2 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
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| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
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| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
| Hammad, N | 1 |
| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
| Xu, X | 1 |
| Zhou, L | 2 |
| Dong, X | 1 |
| Tang, S | 1 |
| Gao, XC | 1 |
| Wei, CH | 1 |
| Zhang, RG | 1 |
| Cai, Q | 1 |
| He, Y | 1 |
| Tong, F | 1 |
| Dong, JH | 1 |
| Wu, G | 2 |
| Dong, XR | 1 |
| Tang, X | 1 |
| Tao, F | 1 |
| Xiang, W | 1 |
| Zhao, Y | 2 |
| Jin, L | 1 |
| Tao, H | 1 |
| Lei, Y | 1 |
| Gan, H | 1 |
| Huang, Y | 2 |
| Chen, Y | 3 |
| Chen, L | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
| Li, Y | 5 |
| Xue, F | 1 |
| Deng, L | 1 |
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| Yan, Z | 2 |
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| Meng, J | 1 |
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| Anastassiadou, M | 1 |
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| Theobald, A | 1 |
| Vagenende, B | 1 |
| Verani, A | 1 |
| Du, L | 1 |
| Liu, X | 1 |
| Ren, Y | 1 |
| Li, J | 7 |
| Li, P | 1 |
| Jiao, Q | 1 |
| Meng, P | 1 |
| Wang, F | 2 |
| Wang, YS | 1 |
| Wang, C | 5 |
| Zhou, X | 2 |
| Wang, W | 1 |
| Hou, J | 1 |
| Zhang, A | 1 |
| Lv, B | 1 |
| Gao, C | 1 |
| Pang, D | 1 |
| Lu, K | 1 |
| Ahmad, NH | 1 |
| Wang, L | 1 |
| Zhu, J | 2 |
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| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
| Qu, Y | 1 |
| Yao, H | 1 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
| Zhao, Q | 1 |
| Hu, W | 1 |
| Zhang, Y | 4 |
| Wu, X | 1 |
| Lu, J | 2 |
| Li, M | 1 |
| Li, W | 2 |
| Wu, W | 1 |
| Du, F | 1 |
| Ji, H | 1 |
| Yang, X | 2 |
| Xu, Z | 1 |
| Wan, L | 1 |
| Wen, Q | 1 |
| Cho, CH | 1 |
| Zou, C | 1 |
| Xiao, Z | 1 |
| Liao, J | 1 |
| Su, X | 1 |
| Bi, Z | 1 |
| Su, Q | 1 |
| Huang, H | 1 |
| Wei, Y | 2 |
| Gao, Y | 2 |
| Na, KJ | 1 |
| Choi, H | 1 |
| Oh, HR | 1 |
| Kim, YH | 1 |
| Lee, SB | 1 |
| Jung, YJ | 1 |
| Koh, J | 1 |
| Park, S | 1 |
| Lee, HJ | 1 |
| Jeon, YK | 1 |
| Chung, DH | 1 |
| Paeng, JC | 1 |
| Park, IK | 1 |
| Kang, CH | 1 |
| Cheon, GJ | 1 |
| Kang, KW | 1 |
| Lee, DS | 1 |
| Kim, YT | 1 |
| Pajuelo-Lozano, N | 1 |
| Alcalá, S | 1 |
| Sainz, B | 1 |
| Perona, R | 1 |
| Sanchez-Perez, I | 1 |
| Logotheti, S | 1 |
| Marquardt, S | 1 |
| Gupta, SK | 1 |
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| Edelhäuser, BAH | 1 |
| Engelmann, D | 1 |
| Brenmoehl, J | 1 |
| Söhnchen, C | 1 |
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| Huang, Z | 1 |
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| Mi, Y | 1 |
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| Zhu, ZQ | 1 |
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| Celestrin, CP | 1 |
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| Saad, MJA | 1 |
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| Chabaud, AG | 1 |
| Landau, I | 1 |
| Novacovic, V | 1 |
| Koerner, M | 1 |
| Alao, AO | 1 |
| Dewan, MJ | 1 |
| Kedar, PS | 1 |
| Ghosh, K | 1 |
| Colah, RB | 1 |
| Mohanty, D | 1 |
| Ehlers, G | 1 |
| Boell, F | 1 |
| Wurm, K | 1 |
| Eberl, R | 1 |
| Skuja, N | 1 |
| Bazyka, DA | 1 |
| Gupta, VK | 1 |
| Gupta, V | 1 |
| Rathi, AK | 1 |
| Gupta, K | 1 |
| Tripathi, BN | 1 |
| Siede, W | 1 |
| Podymova, SD | 2 |
| Bataller Sifré, R | 1 |
| Ortolano Gómez, A | 1 |
| Tebar Massó, J | 1 |
| Berto Navarro, R | 1 |
| Ezedinachi, E | 1 |
| Alaribe, AA | 1 |
| Meremikwu, M | 1 |
| Ejezie, GC | 1 |
| Johns, CJ | 1 |
| Schonfeld, SA | 1 |
| Scott, PP | 1 |
| Zachary, JB | 1 |
| MacGregor, MI | 1 |
| Svenson, KL | 1 |
| Lithell, H | 1 |
| Hällgren, R | 1 |
| Vessby, B | 1 |
| Ito, S | 1 |
| Tamura, T | 2 |
| Nishikawa, M | 1 |
| Dioguardi, N | 1 |
| Braun, HJ | 1 |
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| Wessinghage, D | 1 |
| Miehlke, K | 2 |
| Sharapova, GIa | 1 |
| Khamaganova, AV | 1 |
| Saif, M | 1 |
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| Stancl, I | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study: Safety and Efficacy Study of Tripterygium Wilfordii Hook F Extract in cART-Treated HIV Patients With Poor Immune Responses[NCT02002286] | 23 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| A Randomized, Pilot Study of the Anti-Viral and Anti-Inflammatory Effects of Chloroquine in Early HIV Infection[NCT00308620] | Phase 2/Phase 3 | 13 participants (Actual) | Interventional | 2006-03-31 | Terminated (stopped due to Insufficient financial support; lack of efficacy for primary endpoint) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
HIV-1 viral load change between baseline and 8 weeks (NCT00308620)
Timeframe: baseline and 8 weeks
| Intervention | log10 copies/mL (Log Mean) |
|---|---|
| Chloroquine 250mg or 500mg | -.083 |
| Placebo | 0.0 |
The Change in the percentages of CD38+ HLA-DR+ CD8 and CD4 memory T cells from baseline to 8 weeks. (NCT00308620)
Timeframe: 8 weeks
| Intervention | percentage change (Median) | |
|---|---|---|
| CD8 CD38+HLA-DR+ | CD4 ki67+ | |
| Chloroquine 250mg or 500mg | -2.5 | -2.0 |
| Placebo | 1.85 | 1.4 |
12 reviews available for chloroquine and Chronic Disease
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Chronic cutaneous lupus erythematosus presenting as atypical acneiform and comedonal plaque: case report and literature review.
Topics: Acneiform Eruptions; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Chloroquine; Chronic Di | 2018 |
Itching, chloroquine, and malaria: a review of recent molecular and neuroscience advances and their contribution to mechanistic understanding and therapeutics of chronic non-histaminergic pruritus.
Topics: Action Potentials; Antimalarials; Antipruritics; Black People; Calcium; Chloroquine; Chronic Disease | 2019 |
[New therapeutic strategies for the different subtypes of urticaria].
Topics: Administration, Oral; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Autoimmunity; | 2004 |
Immunological and anti-viral therapy of chronic hepatitis B virus infection.
Topics: Adjuvants, Immunologic; Antibody Formation; Antiviral Agents; Carcinoma, Hepatocellular; Chloroquine | 1980 |
[Therapy of chronic hepatitis (author's transl)].
Topics: Autoimmune Diseases; Azathioprine; Chloroquine; Chronic Disease; Diagnosis, Differential; Hepatitis; | 1981 |
[Sarcoidosis therapy and its problems today].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Anti-Inflammatory Agents; Antineoplasti | 1978 |
[Clinical picture, diagnostics and therapy of amyloidoses].
Topics: Adrenal Gland Diseases; Amyloidosis; Biopsy; Chloroquine; Chronic Disease; Gastrointestinal Diseases | 1972 |
[Chronic polyarthritis. Changes--surgical and conservative treatment].
Topics: Adult; Antibody Formation; Antigen-Antibody Complex; Antineoplastic Agents; Arthritis, Juvenile; Art | 1974 |
[Nephritis].
Topics: Animals; Chloroquine; Chronic Disease; Glucocorticoids; Humans; Nephritis | 1967 |
[Amyloidosis in chronic rheumatic diseases].
Topics: Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Biopsy; Chloroquine; Chronic Disease; Collagen Dise | 1968 |
[Porphyrias].
Topics: Acute Disease; Adenine Nucleotides; Chelating Agents; Chloroquine; Cholestyramine Resin; Chronic Dis | 1969 |
9 trials available for chloroquine and Chronic Disease
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Reduction of immune activation with chloroquine therapy during chronic HIV infection.
Topics: CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Chloroquine; Chronic Diseas | 2010 |
Reduction of immune activation with chloroquine therapy during chronic HIV infection.
Topics: CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Chloroquine; Chronic Diseas | 2010 |
Reduction of immune activation with chloroquine therapy during chronic HIV infection.
Topics: CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Chloroquine; Chronic Diseas | 2010 |
Reduction of immune activation with chloroquine therapy during chronic HIV infection.
Topics: CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Chloroquine; Chronic Diseas | 2010 |
Genotyping of Plasmodium vivax reveals both short and long latency relapse patterns in Kolkata.
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Chronic Disease; Female; Genotype; Genotyping Techniq | 2012 |
[Chloroquine influence on lipid metabolism and selected laboratory parameters].
Topics: Adult; Antimalarials; Blood Sedimentation; Chloroquine; Cholesterol; Chronic Disease; Female; Hemogl | 2005 |
Chloroquine phosphate treatment of chronic Chikungunya arthritis. An open pilot study.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Infectious; Chikungunya virus; Chloroquine; Chroni | 1984 |
Treatment of porphyria cutanea tarda by the effect of chloroquine on the liver.
Topics: Adult; Chloroquine; Chromatography, High Pressure Liquid; Chronic Disease; Female; Humans; Liver; Li | 1995 |
[Comparative results of treating lichen ruber planus by various methods].
Topics: Adolescent; Adult; Aged; Aspirin; Bismuth; Child; Child, Preschool; Chloroquine; Chronic Disease; Cl | 1977 |
[Therapy of chronic hepatitis (author's transl)].
Topics: Azathioprine; Chloroquine; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, | 1979 |
[Treatment of recurrent oral aphthae. A double-blind clinical trial with Ercoquin].
Topics: Adolescent; Adult; Aged; Child; Chloroquine; Chronic Disease; Clinical Trials as Topic; Cortisone; F | 1970 |
87 other studies available for chloroquine and Chronic Disease
| Article | Year |
|---|---|
Brief Report: Retrospective Evaluation on the Efficacy of Lopinavir/Ritonavir and Chloroquine to Treat Nonsevere COVID-19 Patients.
Topics: Adult; Antimalarials; Chloroquine; Chronic Disease; Coronavirus Infections; COVID-19; Drug Combinati | 2020 |
Long-term anti-itch effect of botulinum neurotoxin A is associated with downregulation of TRPV1 and TRPA1 in the dorsal root ganglia in mice.
Topics: Acetone; Animals; Botulinum Toxins, Type A; Chloroquine; Chronic Disease; Disease Models, Animal; Do | 2017 |
MrgprA3 shows sensitization to chloroquine in an acetone-ether-water mice model.
Topics: Acetone; Animals; Calcium; Cations, Divalent; Cells, Cultured; Chloroquine; Chronic Disease; Disease | 2017 |
Cooling Relief of Acute and Chronic Itch Requires TRPM8 Channels and Neurons.
Topics: Animals; Antipruritics; Behavior, Animal; Capsaicin; Chloroquine; Chronic Disease; Cryotherapy; Dise | 2018 |
Chronic hydroxychloroquine/chloroquine exposure for connective tissue diseases and risk of Alzheimer's disease: a population-based cohort study.
Topics: Alzheimer Disease; Antirheumatic Agents; Chloroquine; Chronic Disease; Connective Tissue Diseases; D | 2019 |
Efficacy of Primaquine in Preventing Short- and Long-Latency Plasmodium vivax Relapses in Nepal.
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Chronic Disease; Drug Therapy, Combination; Female; F | 2019 |
Epigallocatechin-3-gallate attenuates impairment of learning and memory in chronic unpredictable mild stress-treated rats by restoring hippocampal autophagic flux.
Topics: Amyloid beta-Peptides; Animals; Autoantigens; Autophagy; CA1 Region, Hippocampal; Catechin; Chloroqu | 2014 |
Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection.
Topics: 4-1BB Ligand; Adoptive Transfer; Animals; Antibodies; CD8-Positive T-Lymphocytes; Chloroquine; Chron | 2012 |
Recurrent cerebellar syndrome following malaria.
Topics: Adult; Antimalarials; Cerebellar Diseases; Chloroquine; Chronic Disease; Drug Resistance; Humans; Ma | 2002 |
Doxycycline and chloroquine as treatment for chronic Q fever endocarditis.
Topics: Anti-Bacterial Agents; Aorta; Chloroquine; Chronic Disease; Coxiella burnetii; Doxycycline; Drug The | 2002 |
[Serological research in chronic inflammatory rheumatism; study of antistreptolysin O].
Topics: Antistreptolysin; Arthritis, Rheumatoid; Chloroquine; Chronic Disease; Humans; Quinacrine; Research; | 1954 |
[Plasmodium berghei in mice; appearance of a state of immunity following repeated treatments with nivaquine during relapse].
Topics: Animals; Chloroquine; Chronic Disease; Immunity; Malaria; Mice; Plasmodium berghei; Quinolines; Recu | 1954 |
[The use of chloroquine in primary chronic arthritis].
Topics: Arthritis; Chloroquine; Chronic Disease | 1958 |
[Treatment of chronic glomerulonephritis of nephrotic form with chloroquine diphosphate].
Topics: Chloroquine; Chronic Disease; Glomerulonephritis; Humans; Nephrotic Syndrome | 1958 |
[On the resochin therapy of primary chronic polyarthritis rheumatica].
Topics: Arthritis, Rheumatoid; Chloroquine; Chronic Disease; Rheumatic Fever | 1959 |
[Treatment of cutaneous allergy with synthetic antimalarials (chronic obstinate urticaria)].
Topics: Antimalarials; Chloroquine; Chronic Disease; Dermatitis, Atopic; Humans; Urticaria | 1961 |
[Acute and chronic chloroquine poisoning; experimental study with rabbits].
Topics: Animals; Blood; Chloroquine; Chronic Disease; Lagomorpha; Poisoning; Rabbits | 1955 |
[Treatment of chronic inflammatory rheumatism with chloroquine and its derivatives].
Topics: Arthritis, Rheumatoid; Chloroquine; Chronic Disease; Humans; Rheumatic Diseases; Rheumatic Fever | 1961 |
Lupus tumidus: a variant of cutaneous lupus erythematosus.
Topics: Adult; Antirheumatic Agents; Chloroquine; Chronic Disease; Female; Humans; Lupus Erythematosus, Cuta | 2004 |
[Treating chronic urticaria].
Topics: Adrenal Cortex Hormones; Adult; Child; Chloroquine; Chronic Disease; Cyclosporine; Dapsone; Diagnosi | 2006 |
[Administration of prostaglandins Ei and immunotherapy in management of various-genesis trophic ulcers].
Topics: Administration, Oral; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Chloroquine; Chronic Dis | 2007 |
[Long-term chloroqine therapy of chronic rheumatic diseases].
Topics: Arthritis, Rheumatoid; Chloroquine; Chronic Disease; Disability Evaluation; Gallbladder Diseases; Ga | 1966 |
[Studies of interstitial cystitis].
Topics: Adult; Animals; Chloroquine; Chronic Disease; Cystitis; Dogs; Female; Humans; Male; Middle Aged; Uri | 1967 |
[Ocular lesions in the treatment of chronic nephritis with chloroquine (report of 62 cases)].
Topics: Adolescent; Adult; Chloroquine; Chronic Disease; Eye Diseases; Female; Humans; Male; Nephritis | 1983 |
Ocular changes after treatment of chronic discoid lupus erythematosus with chloroquine.
Topics: Adolescent; Adult; Child; Chloroquine; Chronic Disease; Eye Diseases; Female; Humans; Lupus Erythema | 1983 |
[Use of delagil to prevent recurrences in patients with chronic bronchitis].
Topics: Adult; Anti-Inflammatory Agents; Bronchitis; Chloroquine; Chronic Disease; Humans; Middle Aged | 1984 |
The effect of some antirheumatic drugs in vivo on the response of spleen cells to concanavalin A in rats with chronic inflammation.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Chloroquine; Chronic Disease; Concanavalin A; Female; Go | 1982 |
[Use of the preparation essentiale in the therapy of lupus erythematosus].
Topics: Adolescent; Adult; Aged; Aspirin; Chloroquine; Chronic Disease; Drug Combinations; Drug Evaluation; | 1983 |
[Drug therapy of rheumatoid arthritis].
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Bee Venoms; Chloroquine; Chronic Disease; Drug Therapy | 1980 |
Sarcoidosis. Part 2. More on the differential diagnosis. The usual course. Treatments of choice. Prognosis.
Topics: 4-Aminobenzoic Acid; Acute Disease; Adrenal Cortex Hormones; Adult; Alveolitis, Extrinsic Allergic; | 1980 |
Angioimmunoblastic lymphadenopathy associated with chronic Plasmodium malariae infection.
Topics: Antimalarials; Chloroquine; Chronic Disease; Humans; Immunoblastic Lymphadenopathy; Malaria; Male; M | 1981 |
[Acute cholecystitis and clonorchis sinensis infection].
Topics: Bile Ducts; Chloroquine; Cholecystitis; Chronic Disease; Clonorchiasis; Clonorchis sinensis; Humans; | 1981 |
[Bilateral edema of optic nerve (toxic edema) during therapy with chloroquine because of p.c.P. ].
Topics: Arthritis, Rheumatoid; Chloroquine; Chronic Disease; Female; Humans; Male; Middle Aged; Papilledema | 1982 |
Management of juvenile rheumatoid arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Arthritis, Juvenile; Aspirin; Child; Chloroquine; Chroni | 1981 |
Persistent fever in severe malaria in children.
Topics: Anti-Bacterial Agents; Child; Child, Preschool; Chloroquine; Chronic Disease; Drug Resistance; Femal | 1994 |
Proliferative glomerulonephritis revealing chronic Q fever.
Topics: Aged; Anti-Bacterial Agents; Chloroquine; Chronic Disease; Coxiella burnetii; Cryoglobulinemia; Doxy | 1996 |
Diagnosis and treatment of ILD.
Topics: Bronchoalveolar Lavage; Child; Chloroquine; Chronic Disease; Female; Humans; Infant; Lung Diseases, | 1997 |
Chronic cerebral malaria--is there such a clinical entity?
Topics: Antimalarials; Chloroquine; Chronic Disease; Diabetes Complications; Diabetic Coma; Humans; Malaria, | 1995 |
Is chronic ulcerative stomatitis an entity? Clinical and immunological findings in 18 cases.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Antimalarials; Chloroquine; Chronic Disease | 1998 |
Development of irreversible lesions in the brain, heart and kidney following acute and chronic murine malaria infection.
Topics: Acute Disease; Animals; Antimalarials; Brain; Chloroquine; Chronic Disease; Kidney; Malaria; Mice; M | 1999 |
Chronic urticaria serum induces histamine release, leukotriene production, and basophil CD63 surface expression--inhibitory effects ofanti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Antigens, CD; Antigens, Surface; Basophils; Chloroquine; Chronic Disease; | 2000 |
Psychiatric complications of malaria: a case report.
Topics: Acute Disease; Adult; Antimalarials; Brain; Chloroquine; Chronic Disease; Humans; Malaria, Falciparu | 2001 |
Chronic persistent hemolysis in an infant: can we afford to forget malaria as a cause?
Topics: Anemia, Hemolytic; Chloroquine; Chronic Disease; Humans; Infant; Infectious Disease Transmission, Ve | 2002 |
[Leishmaniasis cutanes recidivans. Report of a case].
Topics: Adult; Biopsy; Chloroquine; Chronic Disease; Dihydrostreptomycin Sulfate; Humans; Leishmaniasis, Muc | 1975 |
[Basic treatment for chronic polyarthritis].
Topics: Arthritis; Chloroquine; Chronic Disease; Gold; Humans; Immunosuppressive Agents; Mouth Mucosa; Penic | 1977 |
[Clinical aspects and therapy of chronic pancreatitis].
Topics: 4-Aminobenzoic Acid; Alcoholism; Amylases; Chloroquine; Chronic Disease; Chymotrypsin; Diabetes Mell | 1979 |
The chloroquine resistant chronic Vivax malaria presenting as malarial cachexia and secondary hypersplenism: (a case report).
Topics: Adolescent; Cachexia; Chloroquine; Chronic Disease; Drug Resistance, Microbial; Female; Humans; Hype | 1978 |
[Immunodepressive treatment of chronic liver diseases].
Topics: Chloroquine; Chronic Disease; Hepatitis; Humans; Prednisolone | 1976 |
[Favorable effect of chloroquine on chronic refractory subaggressive hepatitis].
Topics: Azathioprine; Chloroquine; Chronic Disease; Drug Evaluation; Hepatitis; Humans; Male; Middle Aged; P | 1975 |
[Delagil in treatment of chronic hepatitis].
Topics: Adult; Chloroquine; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Hepatitis; Humans; | 1975 |
New trends in chloroquine efficacy in the treatment of malaria: significance of low (scanty) parasitaemia in an endemic area, with emerging chloroquine-resistant P. falciparum.
Topics: Adult; Animals; Child; Child, Preschool; Chloroquine; Chronic Disease; Drug Resistance; Female; Huma | 1992 |
Longitudinal study of chronic sarcoidosis with low-dose maintenance corticosteroid therapy. Outcome and complications.
Topics: Adult; Black People; Chloroquine; Chronic Disease; Female; Follow-Up Studies; Humans; Lung Diseases; | 1986 |
Serum lipoprotein in active rheumatoid arthritis and other chronic inflammatory arthritides. II. Effects of anti-inflammatory and disease-modifying drug treatment.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis | 1987 |
Effects of desiccated thyroid, prednisolone and chloroquine on goiter and antibody titer in chronic thyroiditis.
Topics: Agglutination Tests; Autoantibodies; Autoimmune Diseases; Chloroquine; Chronic Disease; Complement F | 1968 |
[Clinical studies on chronic thyroiditis with reference to thyroid antibodies in the blood].
Topics: Animals; Antibodies; Chloroquine; Chromatography; Chronic Disease; Complement Fixation Tests; gamma- | 1967 |
[The treatment of chronic hepatitis (author's transl)].
Topics: Adrenal Cortex Hormones; Antimetabolites; Azathioprine; Chloroquine; Chronic Disease; Hepatitis; Hum | 1974 |
[What is assured in the treatment of chronic inflammatory joint disease?].
Topics: Chloroquine; Chronic Disease; Gold; Humans; Immunosuppressive Agents; Inflammation; Joint Diseases; | 1972 |
[Treatment of some dermatoses by the intradermal injections of a 10 percent solution of quingamine].
Topics: Adult; Chloroquine; Chronic Disease; Female; Humans; Injections, Intradermal; Keloid; Lupus Erythema | 1973 |
Treatment of amoebiasis.
Topics: Acute Disease; Amebiasis; Anti-Bacterial Agents; Chloroquine; Chronic Disease; Dysentery, Amebic; Eg | 1973 |
[Histomorphology and histochemistry of changes in the dermo-epidermal area in lupus erythematosus prior to and following treatment with chloroquine phosphate].
Topics: Cell Membrane Permeability; Chloroquine; Chronic Disease; Female; Humans; Lupus Erythematosus, Syste | 1973 |
[Chronic lupus erythematosus with less typical localization. Case report].
Topics: Adult; Chloroquine; Chronic Disease; Ear, External; Female; Humans; Lip Diseases; Lupus Erythematosu | 1973 |
Chronic intestinal coccidiosis in man: intestinal morphology and response to treatment.
Topics: Antiprotozoal Agents; Biopsy; Chloroquine; Chronic Disease; Coccidiosis; Diagnosis, Differential; Di | 1974 |
[Incidence of chronic gastritis in progressive chronic polyarthritis].
Topics: Adult; Aged; Antibody Formation; Antibody-Producing Cells; Arthritis, Rheumatoid; Autoantibodies; Ch | 1974 |
[Treatment of chronic intestinal amebiasis with the compound of diiodohydroxyquinoline, tetracycline and chloroquine].
Topics: Amebiasis; Chloroquine; Chronic Disease; Humans; Iodoquinol; Tetracycline | 1966 |
[Therapy of sarcoidosis].
Topics: Acute Disease; Chloroquine; Chronic Disease; Female; Glucocorticoids; Humans; Oxyphenbutazone; Pregn | 1969 |
Malaria in soldiers returning from Vietnam. Epidemiologic, therapeutic, and clinical studies.
Topics: Adult; Black or African American; Black People; Chloroquine; Chronic Disease; Hospitalization; Human | 1970 |
The routine treatment of malaria.
Topics: Acute Disease; Adolescent; Adult; Amodiaquine; Child; Child, Preschool; Chloroquine; Chronic Disease | 1971 |
Immunological studies with simian malarias. I. Antigenic variants of Plasmodium cynomolgi bastianellii.
Topics: Animals; Anopheles; Antigens; Blood; Chloroquine; Chronic Disease; Female; Haplorhini; Immunity; Mal | 1969 |
Immunological studies with simian malarias. II. Heterologous immunity in the "cynomolgi" group.
Topics: Animals; Blood; Chloroquine; Chronic Disease; Haplorhini; Immunity; Malaria; Plasmodium; Species Spe | 1969 |
Observations on the relapse activity of Plasmodium fieldi in the rhesus monkey.
Topics: Aedes; Animals; Chloroquine; Chronic Disease; Disease Models, Animal; Haplorhini; Insect Vectors; Ma | 1971 |
[Treatment of chronic glomerulonephritis and pyelonephritis].
Topics: Anti-Bacterial Agents; Benzimidazoles; Chloroquine; Chronic Disease; Diet Therapy; Glomerulonephriti | 1971 |
[Complex delagil and sulfadimezin therapy in persons with acquired chronic toxoplasmosis].
Topics: Adult; Chloroquine; Chronic Disease; Female; Humans; Male; Middle Aged; Sulfamethazine; Toxoplasmosi | 1971 |
[Critic of rheumatism therapy in the practice].
Topics: Adrenal Cortex Hormones; Ambulatory Care; Arthritis, Rheumatoid; Chloroquine; Chronic Disease; Famil | 1967 |
[Resochine therapy in chronic hepatitis?].
Topics: Chloroquine; Chronic Disease; Hepatitis; Humans | 1969 |
[Therapy of chronic brucellosis with chloroquine and glucocorticoids].
Topics: Brucellosis; Chloroquine; Chronic Disease; Glucocorticoids; Humans | 1969 |
[Modern conception of a causal management of chronic polyarthritis].
Topics: Antigen-Antibody Complex; Arthritis; Chloroquine; Chronic Disease; Gold; Humans; Immunosuppressive A | 1969 |
A case of primary amoebic meningoencephalitis treated with chloroquine.
Topics: Adult; Amebiasis; Chloroquine; Chronic Disease; Humans; Male; Meningoencephalitis | 1970 |
Relapse after standard treatment of malaria.
Topics: Adult; Chloroquine; Chronic Disease; Humans; Malaria; Male; Primaquine | 1970 |
[Diffuse interstitial pulmonary fibrosis (Hamman-Rich syndrome) and primary chronic polyarthritis].
Topics: Adult; Arthritis, Rheumatoid; Chloroquine; Chronic Disease; Female; Humans; Oxytetracycline; Phospha | 1971 |
[Treatment of chronic acquired toxoplasmosis].
Topics: Ascorbic Acid; Chloroquine; Chronic Disease; Humans; Prednisolone; Promethazine; Pyrimethamine; Sulf | 1971 |
[Erythematodes familiaris].
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Chloroquine; Chronic Disease; | 1968 |
Agents which cause pigmentary retinopathy.
Topics: Antibiotics, Antineoplastic; Chloroquine; Chlorpromazine; Chronic Disease; Female; Humans; Iodine; M | 1968 |
[Intra-articular corticotherapy in chronic joint diseases].
Topics: Chloroquine; Chronic Disease; Gold; Humans; Hydrocortisone; Injections, Intra-Articular; Joint Disea | 1968 |
[A case of chloroquine retinopathy].
Topics: Adult; Chloroquine; Chronic Disease; Eye Diseases; Female; Humans; Nephritis; Retina; Visual Fields | 1968 |
[Internal therapy of chronic polyarthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Balneology; Chloroquine; Chronic Disease; Exercise | 1969 |
Management of sarcoidosis.
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Aminobenzoates; Calcium; Child; Chloroquine; Chronic | 1969 |
[Trial of resochin therapy in diffuse kidney diseases].
Topics: Amyloidosis; Animals; Chloroquine; Chronic Disease; Collagen Diseases; Glomerulonephritis; Humans; K | 1966 |