chloroquine has been researched along with Cerebral Malaria in 49 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These findings suggest that chloroquine does not play an important role in the aetiology of seizures in childhood cerebral malaria." | 9.09 | Chloroquine is not a risk factor for seizures in childhood cerebral malaria. ( Crawley, J; Kokwaro, G; Marsh, K; Ouma, D; Watkins, W, 2000) |
| " falciparum in a high-throughput in vitro assay and to protect mice against lethal cerebral malaria caused by Plasmodium berghei ANKA when used alone or in combination with established antimalarial drugs." | 5.40 | Treatment of murine cerebral malaria by artemisone in combination with conventional antimalarial drugs: antiplasmodial effects and immune responses. ( Clark, J; Golenser, J; Guiguemde, WA; Guo, J; Guy, RK; Haynes, RK; Hunt, NH; Marciano, A, 2014) |
| "However, their efficiency in cases of cerebral malaria (CM) remains to be determined." | 5.36 | Artemisone effective against murine cerebral malaria. ( Barenholz, Y; Bentura-Marciano, A; Chan, HW; Chan, WC; Golenser, J; Haynes, RK; Hunt, N; McQuillan, JA; Waknine-Grinberg, JH, 2010) |
| "These findings suggest that chloroquine does not play an important role in the aetiology of seizures in childhood cerebral malaria." | 5.09 | Chloroquine is not a risk factor for seizures in childhood cerebral malaria. ( Crawley, J; Kokwaro, G; Marsh, K; Ouma, D; Watkins, W, 2000) |
| " We tested whether chloroquine- and antifolate drug-resistant genotypes would be more commonly associated with cases of cerebral malaria than with cases of mild malaria in the province of Jabalpur, India, by genotyping the dhps, dhfr, pfmdr-1, and pfcrt genes using pyrosequencing, direct sequencing, and real-time PCR." | 3.76 | Evidence of selective sweeps in genes conferring resistance to chloroquine and pyrimethamine in Plasmodium falciparum isolates in India. ( Dash, AP; Jain, V; McCollum, AM; Mixson-Hayden, T; Nagpal, AC; Poe, A; Singh, N; Stiles, JK; Udhayakumar, V, 2010) |
| "United States military personnel deployed to Somalia were at risk for malaria, including chloroquine-resistant Plasmodium falciparum malaria." | 3.69 | Malaria among United States troops in Somalia. ( Batchelor, R; Burans, JP; Iriye, C; Lobel, HO; Longer, CF; Magill, AJ; Rozmajzl, P; Sharp, TW; Smoak, B; Thornton, SA; Wallace, MR, 1996) |
| "Plasmodium falciparum sensitivity to quinine in São Tomé was determined by in vivo and in vitro tests in 56 children with mild or cerebral malaria." | 3.69 | Plasmodium falciparum chloroquine and quinine sensitivity in asymptomatic and symptomatic children in São Tomé Island. ( Baptista, JL; D'Alessandro, U; Das Neves, I; Hendrix, L; Wéry, M, 1997) |
| "Currently, most of the subjects presenting with Plasmodium falciparum malaria in France come from areas where chloroquine resistance has already been reported." | 3.68 | [Treatment of malaria in children in France]. ( Badoual, J, 1992) |
| " The median relative bioavailability of dihydroartemisinin (DHA), the active antimalarial metabolite of ARS, was higher in the low-dose i." | 2.70 | Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria. ( Agbenyega, T; Agranoff, D; Appiah, JA; Bedu-Addo, G; Krishna, S; Mansor, SM; Navaratnam, V; Owusu-Ofori, AK; Planche, T; Ramanathan, S; Woodrow, C, 2001) |
| "Children with deep coma (scoring 0-2) had significantly longer duration of coma before presentation (P = 0." | 2.68 | Predictors of severity of illness on presentation in children with cerebral malaria. ( Biemba, G; Gordeuk, VR; Khumalo, H; Mabeza, GF; Moyo, VM; Nyarugwe, P; Parry, D; Thuma, PE; Zulu, S, 1995) |
| "Rarely, cerebral malaria is a presenting complication or occurs during the course of P." | 2.43 | Cerebral malaria owing to Plasmodium vivax: case report. ( Atambay, M; Daldal, N; Gungor, S; Ozen, M, 2006) |
| "Malaria is an infectious disease of major worldwide clinical importance that causes a variety of severe, or complicated, syndromes including cerebral malaria, which is often fatal." | 1.51 | Integrin αDβ2 influences cerebral edema, leukocyte accumulation and neurologic outcomes in experimental severe malaria. ( Azevedo-Quintanilha, IG; Bozza, PT; Campbell, RA; Castro-Faria-Neto, HC; Estato, V; Ferreira, AC; Nascimento, DO; Reis, PA; Silva, TI; Vieira-de-Abreu, A; Weyrich, AS; Zimmerman, GA, 2019) |
| " falciparum in a high-throughput in vitro assay and to protect mice against lethal cerebral malaria caused by Plasmodium berghei ANKA when used alone or in combination with established antimalarial drugs." | 1.40 | Treatment of murine cerebral malaria by artemisone in combination with conventional antimalarial drugs: antiplasmodial effects and immune responses. ( Clark, J; Golenser, J; Guiguemde, WA; Guo, J; Guy, RK; Haynes, RK; Hunt, NH; Marciano, A, 2014) |
| "In vivo protection against cerebral malaria was observed with the phenazines 11, 12, 20, and 27, whereas partial protection was provided by 19." | 1.37 | A new class of phenazines with activity against a chloroquine resistant Plasmodium falciparum strain and antimicrobial activity. ( Hoerauf, A; Hussain, H; Krohn, K; Saeftel, M; Sarite, SR; Schulz, B; Specht, S, 2011) |
| "However, their efficiency in cases of cerebral malaria (CM) remains to be determined." | 1.36 | Artemisone effective against murine cerebral malaria. ( Barenholz, Y; Bentura-Marciano, A; Chan, HW; Chan, WC; Golenser, J; Haynes, RK; Hunt, N; McQuillan, JA; Waknine-Grinberg, JH, 2010) |
| "Human cerebral malaria causes neurological and behavioral deficits which persist long after resolution of infection and clearance of parasites with antimalarial drugs." | 1.36 | Persistent cognitive and motor deficits after successful antimalarial treatment in murine cerebral malaria. ( Dai, M; Desruisseaux, MS; Gulinello, M; Reznik, SE; Spray, DC; Tanowitz, HB; Weiss, LM, 2010) |
| "The main clinical features concerning cerebral malaria, diagnostic tools and therapeutic measures are discussed." | 1.33 | [Imported cerebral malaria]. ( Guillon, B; Maiga, Y; Yatim, D, 2005) |
| "Quinine is the drug of choice for the treatment of cerebral malaria 87." | 1.32 | Assessment of doctors' management of severe malaria in urban centres in Eastern Nigeria. ( Ele, PU; Ibeh, CC; Ukpabi, OJ, 2004) |
| "One case of cerebral malaria was noted." | 1.30 | [Malaria in an urban environment: the case of the city of Rufisque in Senegal]. ( Diallo, S; Dieng, Y; Faye, O; Feller-Dansokho, E; Gaye, O; Lakh, NC; Ndir, O, 1997) |
| "There were 26 cases of cerebral malaria, with a death rate of 34." | 1.29 | [Malaria in children at the Sihanoukville Hospital (Cambodia)]. ( Imbert, P; Martin, YN; Migliani, R; Pheng, S; Sokhan, C; Yen, KK, 1994) |
| "There is now considerable evidence that cerebral malaria may be related to the over-production of tumour necrosis factor (TNF)." | 1.29 | Chloroquine-induced inhibition of the production of TNF, but not of IL-6, is affected by disruption of iron metabolism. ( Ambroise-Thomas, P; Barbe, G; Donadille, A; Peyron, F; Picot, S; Vuillez, JP, 1993) |
| "Of the 134 seizure cases seen, febrile convulsion (FC) formed the majority (55%) with cerebral malaria (CM) as the only major (33%) rival." | 1.29 | Upsurge of malaria-related convulsions in a paediatric emergency room in Nigeria. Consequence of emergence of chloroquine-resistant Plasmodium falciparum. ( Asindi, AA; Ekanem, EE; Ibia, EO; Nwangwa, MA, 1993) |
| "The utility of the Glasgow coma scale and quantitative assessment of parasitaemia levels as diagnostic and prognostic indices in cerebral malaria were determined in this study." | 1.28 | Pediatric cerebral malaria in Accra, Ghana. ( Bia, FJ; Commey, JO; Osei, L; Wolf-Gould, C, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 24 (48.98) | 18.2507 |
| 2000's | 11 (22.45) | 29.6817 |
| 2010's | 12 (24.49) | 24.3611 |
| 2020's | 2 (4.08) | 2.80 |
| Authors | Studies |
|---|---|
| Bertinaria, M | 1 |
| Guglielmo, S | 1 |
| Rolando, B | 1 |
| Giorgis, M | 1 |
| Aragno, C | 1 |
| Fruttero, R | 1 |
| Gasco, A | 1 |
| Parapini, S | 1 |
| Taramelli, D | 1 |
| Martins, YC | 1 |
| Carvalho, LJ | 1 |
| Hussain, H | 1 |
| Specht, S | 1 |
| Sarite, SR | 1 |
| Saeftel, M | 1 |
| Hoerauf, A | 1 |
| Schulz, B | 1 |
| Krohn, K | 1 |
| Royo, J | 1 |
| Camara, A | 1 |
| Bertrand, B | 1 |
| Batigne, P | 1 |
| Coste, A | 1 |
| Pipy, B | 1 |
| Aubouy, A | 1 |
| Ficko, C | 1 |
| Conan, PL | 1 |
| Azevedo-Quintanilha, IG | 1 |
| Vieira-de-Abreu, A | 1 |
| Ferreira, AC | 1 |
| Reis, PA | 3 |
| Silva, TI | 1 |
| Nascimento, DO | 1 |
| Campbell, RA | 1 |
| Estato, V | 2 |
| Weyrich, AS | 1 |
| Bozza, PT | 2 |
| Zimmerman, GA | 2 |
| Castro-Faria-Neto, HC | 3 |
| Guiguemde, WA | 1 |
| Hunt, NH | 1 |
| Guo, J | 1 |
| Marciano, A | 1 |
| Haynes, RK | 2 |
| Clark, J | 1 |
| Guy, RK | 1 |
| Golenser, J | 2 |
| Mixson-Hayden, T | 1 |
| Jain, V | 1 |
| McCollum, AM | 1 |
| Poe, A | 1 |
| Nagpal, AC | 1 |
| Dash, AP | 1 |
| Stiles, JK | 1 |
| Udhayakumar, V | 1 |
| Singh, N | 1 |
| Waknine-Grinberg, JH | 1 |
| Hunt, N | 1 |
| Bentura-Marciano, A | 1 |
| McQuillan, JA | 1 |
| Chan, HW | 1 |
| Chan, WC | 1 |
| Barenholz, Y | 1 |
| Dai, M | 2 |
| Reznik, SE | 2 |
| Spray, DC | 2 |
| Weiss, LM | 2 |
| Tanowitz, HB | 2 |
| Gulinello, M | 1 |
| Desruisseaux, MS | 2 |
| Bruce-Hickman, D | 1 |
| Zhu, X | 1 |
| Pan, Y | 1 |
| Li, Y | 1 |
| Jiang, Y | 1 |
| Shang, H | 1 |
| Gowda, DC | 1 |
| Cui, L | 1 |
| Cao, Y | 1 |
| Comim, CM | 1 |
| Frutuoso, VS | 1 |
| Fries, GR | 1 |
| Fraga, DB | 1 |
| Kapczinski, F | 1 |
| Zugno, AI | 1 |
| Barichello, T | 1 |
| Quevedo, J | 1 |
| Freeman, B | 1 |
| Shikani, HJ | 1 |
| Bruno, FP | 1 |
| Collado, JE | 1 |
| Macias, R | 1 |
| Davies, P | 1 |
| da Silva, TI | 1 |
| d'Avila, JC | 1 |
| Siqueira, LD | 1 |
| Assis, EF | 1 |
| Bozza, FA | 1 |
| Tibiriça, EV | 1 |
| Gumede, B | 1 |
| Folb, P | 1 |
| Ryffel, B | 1 |
| Hoelscher, M | 1 |
| Löscher, T | 1 |
| Conte, R | 1 |
| Tassi, C | 1 |
| Belletti, D | 1 |
| Ricci, F | 1 |
| Tazzari, PL | 1 |
| Ibeh, CC | 1 |
| Ele, PU | 1 |
| Ukpabi, OJ | 1 |
| Maiga, Y | 1 |
| Yatim, D | 1 |
| Guillon, B | 1 |
| Meerman, L | 1 |
| Ord, R | 1 |
| Bousema, JT | 1 |
| van Niekerk, M | 1 |
| Osman, E | 1 |
| Hallett, R | 1 |
| Pinder, M | 1 |
| Walraven, G | 1 |
| Sutherland, CJ | 1 |
| Ozen, M | 1 |
| Gungor, S | 1 |
| Atambay, M | 1 |
| Daldal, N | 1 |
| Sharma, YD | 1 |
| Kant, R | 1 |
| Pillai, CR | 1 |
| Ansari, MA | 1 |
| Fillai, U | 1 |
| Mabeza, GF | 1 |
| Moyo, VM | 1 |
| Thuma, PE | 1 |
| Biemba, G | 1 |
| Parry, D | 1 |
| Khumalo, H | 1 |
| Nyarugwe, P | 1 |
| Zulu, S | 1 |
| Gordeuk, VR | 1 |
| Imbert, P | 1 |
| Yen, KK | 1 |
| Migliani, R | 1 |
| Sokhan, C | 1 |
| Martin, YN | 1 |
| Pheng, S | 1 |
| Epstein, JE | 1 |
| Dyer, BJ | 1 |
| Tunnessen, WW | 1 |
| Picot, S | 2 |
| Peyron, F | 1 |
| Donadille, A | 1 |
| Vuillez, JP | 1 |
| Barbe, G | 1 |
| Ambroise-Thomas, P | 2 |
| Asindi, AA | 1 |
| Ekanem, EE | 1 |
| Ibia, EO | 1 |
| Nwangwa, MA | 1 |
| Wallace, MR | 1 |
| Sharp, TW | 1 |
| Smoak, B | 1 |
| Iriye, C | 1 |
| Rozmajzl, P | 1 |
| Thornton, SA | 1 |
| Batchelor, R | 1 |
| Magill, AJ | 1 |
| Lobel, HO | 1 |
| Longer, CF | 1 |
| Burans, JP | 1 |
| Tilluckdharry, CC | 1 |
| Chadee, DD | 1 |
| Doon, R | 1 |
| Nehall, J | 1 |
| Prada, J | 1 |
| Müller, S | 1 |
| Bienzle, U | 1 |
| Kremsner, PG | 1 |
| Nkwelle Akede, A | 1 |
| Chaulet, JF | 1 |
| Tetanye, E | 1 |
| Ringwald, P | 1 |
| Prévosto, JM | 1 |
| Boudin, C | 1 |
| Baptista, JL | 1 |
| Das Neves, I | 1 |
| D'Alessandro, U | 1 |
| Hendrix, L | 1 |
| Wéry, M | 1 |
| Mahapatra, SK | 1 |
| Hviid, L | 1 |
| Kurtzhals, JA | 1 |
| Goka, BQ | 2 |
| Oliver-Commey, JO | 1 |
| Nkrumah, FK | 1 |
| Theander, TG | 1 |
| al-Yaman, F | 1 |
| Genton, B | 1 |
| Mokela, D | 1 |
| Narara, A | 1 |
| Raiko, A | 1 |
| Alpers, MP | 1 |
| Gaye, O | 1 |
| Faye, O | 2 |
| Ndir, O | 1 |
| Feller-Dansokho, E | 1 |
| Dieng, Y | 1 |
| Lakh, NC | 1 |
| Diallo, S | 1 |
| Novitzky, N | 1 |
| Alrajhi, AA | 1 |
| Rahim, I | 1 |
| Akood, M | 1 |
| Hazmi, M | 1 |
| Mirete Ferrer, C | 1 |
| Masiá Canuto, M | 1 |
| Navarro Ruiz, A | 1 |
| Gutiérrez Rodero, F | 1 |
| Krishna, S | 1 |
| Planche, T | 1 |
| Agbenyega, T | 1 |
| Woodrow, C | 1 |
| Agranoff, D | 1 |
| Bedu-Addo, G | 1 |
| Owusu-Ofori, AK | 1 |
| Appiah, JA | 1 |
| Ramanathan, S | 1 |
| Mansor, SM | 1 |
| Navaratnam, V | 1 |
| Crawley, J | 1 |
| Kokwaro, G | 1 |
| Ouma, D | 1 |
| Watkins, W | 1 |
| Marsh, K | 1 |
| Adabayeri, V | 1 |
| Ofori-Adjei, E | 1 |
| Quarshie, B | 1 |
| Asare-Odei, G | 1 |
| Akanmori, BD | 1 |
| Kurtzhals, J | 1 |
| Ofori-Adjei, D | 1 |
| Neequaye, J | 1 |
| Badoual, J | 1 |
| Churchill, D | 1 |
| Davidson, R | 1 |
| O'Flynn, K | 1 |
| Kox, W | 1 |
| Chaudhary, HR | 1 |
| Meena, SR | 1 |
| Jani, D | 1 |
| Tiwari, U | 1 |
| Goyal, RK | 1 |
| Nagatake, T | 1 |
| Hoang, VT | 1 |
| Tegoshi, T | 1 |
| Rabbege, J | 1 |
| Ann, TK | 1 |
| Aikawa, M | 1 |
| Salord, F | 1 |
| Allaouchiche, B | 1 |
| Gaussorgues, P | 1 |
| Boibieux, A | 1 |
| Sirodot, M | 1 |
| Gerard-Boncompain, M | 1 |
| Biron, F | 1 |
| Peyramond, D | 1 |
| Robert, D | 1 |
| Wolf-Gould, C | 1 |
| Osei, L | 1 |
| Commey, JO | 1 |
| Bia, FJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Early Atorvastatin Treatment During the Acute Phase of Stroke on Immunoinflammatory Markers and Outcome in Patients With Acute Ischemic Stroke Classified as LAAS According TOAST Classification[NCT02225834] | Phase 4 | 50 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chloroquine and Cerebral Malaria
| Article | Year |
|---|---|
Cerebral malaria owing to Plasmodium vivax: case report.
Topics: Animals; Antimalarials; Brain; Child, Preschool; Chloroquine; Humans; Malaria, Cerebral; Malaria, Vi | 2006 |
4 trials available for chloroquine and Cerebral Malaria
| Article | Year |
|---|---|
Predictors of severity of illness on presentation in children with cerebral malaria.
Topics: Age of Onset; Anemia; Child, Preschool; Chloroquine; Coma; Double-Blind Method; Drug Resistance; Fem | 1995 |
Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquin | 2001 |
Chloroquine is not a risk factor for seizures in childhood cerebral malaria.
Topics: Adolescent; Antimalarials; Child; Child, Preschool; Chloroquine; Double-Blind Method; Female; Humans | 2000 |
Comparison of chloroquine with artesunate in the treatment of cerebral malaria in Ghanaian children.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Female; Ghan | 2001 |
44 other studies available for chloroquine and Cerebral Malaria
| Article | Year |
|---|---|
Amodiaquine analogues containing NO-donor substructures: synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria.
Topics: Amodiaquine; Animals; Antiprotozoal Agents; Aorta, Thoracic; Chemistry, Physical; Malaria, Cerebral; | 2011 |
A new class of phenazines with activity against a chloroquine resistant Plasmodium falciparum strain and antimicrobial activity.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Malaria, Cerebral; Mice; Mice, Inbred C57BL; P | 2011 |
Kinetics of monocyte subpopulations during experimental cerebral malaria and its resolution in a model of late chloroquine treatment.
Topics: Animals; Brain; CD36 Antigens; Chloroquine; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Monocytes | 2022 |
[Malaria in 2022: clinical and therapeutic aspects].
Topics: Antimalarials; Chloroquine; Humans; Malaria, Cerebral; Plasmodium; Quinine | 2023 |
Integrin αDβ2 influences cerebral edema, leukocyte accumulation and neurologic outcomes in experimental severe malaria.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; CD11 Antigens; Chloroquine; Disease Models, Animal | 2019 |
Treatment of murine cerebral malaria by artemisone in combination with conventional antimalarial drugs: antiplasmodial effects and immune responses.
Topics: Animals; Antimalarials; Artemisinins; Cell Line; Cell Survival; Cells, Cultured; Chloroquine; Doxycy | 2014 |
Evidence of selective sweeps in genes conferring resistance to chloroquine and pyrimethamine in Plasmodium falciparum isolates in India.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Genes, Protozoan; Genotype; Humans; India; Mal | 2010 |
Artemisone effective against murine cerebral malaria.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Therapy, Combination; Malaria, Cerebral; Mal | 2010 |
Persistent cognitive and motor deficits after successful antimalarial treatment in murine cerebral malaria.
Topics: Animals; Antimalarials; Chloroquine; Cognition Disorders; Disease Models, Animal; Female; Malaria, C | 2010 |
Oxygen therapy for cerebral malaria.
Topics: Chloroquine; Combined Modality Therapy; Humans; Hyperbaric Oxygenation; Malaria, Cerebral | 2011 |
Targeting Toll-like receptors by chloroquine protects mice from experimental cerebral malaria.
Topics: Animals; Antimalarials; Cells, Cultured; Chloroquine; Cytokines; Dendritic Cells; Disease Models, An | 2012 |
Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice.
Topics: Acetylcholinesterase; Animals; Antimalarials; Brain-Derived Neurotrophic Factor; Chloroquine; Habitu | 2012 |
Altered regulation of Akt signaling with murine cerebral malaria, effects on long-term neuro-cognitive function, restoration with lithium treatment.
Topics: Acute Disease; Animals; Chloroquine; Cognition; Female; Fluorescent Antibody Technique; Glycogen Syn | 2012 |
Statins decrease neuroinflammation and prevent cognitive impairment after cerebral malaria.
Topics: Animals; Brain; CD11b Antigen; Chemokines; Chloroquine; Cognition Disorders; Cytokines; Edema; Endot | 2012 |
Oral artesunate prevents Plasmodium berghei Anka infection in mice.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Therapy, C | 2003 |
[Malaria--case report].
Topics: Adult; Anti-Infective Agents; Antidiarrheals; Antimalarials; Chloroquine; Ciprofloxacin; Diarrhea; E | 2003 |
Autoimmune thrombocytopenia in malaria.
Topics: Antimalarials; Autoantibodies; Chloroquine; Erythrocyte Transfusion; Humans; Malaria, Cerebral; Mala | 2003 |
Assessment of doctors' management of severe malaria in urban centres in Eastern Nigeria.
Topics: Adult; Analgesics; Analgesics, Non-Narcotic; Anemia; Antimalarials; Blood Transfusion; Chloroquine; | 2004 |
[Imported cerebral malaria].
Topics: Adult; Antimalarials; Chloroquine; Drug Resistance; Female; France; Humans; Malaria, Cerebral; Malar | 2005 |
Carriage of chloroquine-resistant parasites and delay of effective treatment increase the risk of severe malaria in Gambian children.
Topics: Alleles; Anemia; Animals; ATP-Binding Cassette Transporters; Case-Control Studies; Child; Child, Pre | 2005 |
Cerebral malaria.
Topics: Animals; Chloroquine; Disease Outbreaks; Drug Resistance; Humans; India; Malaria, Cerebral; Plasmodi | 1995 |
[Malaria in children at the Sihanoukville Hospital (Cambodia)].
Topics: Cambodia; Child; Chloroquine; Hospitals; Humans; Malaria; Malaria, Cerebral; Malaria, Falciparum; Ma | 1994 |
Picture of the month. Cerebral malaria.
Topics: Antimalarials; Chloroquine; Humans; Infant; Malaria, Cerebral | 1993 |
Chloroquine-induced inhibition of the production of TNF, but not of IL-6, is affected by disruption of iron metabolism.
Topics: Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Homeostasis; Humans; Interleukin-6; Ir | 1993 |
Upsurge of malaria-related convulsions in a paediatric emergency room in Nigeria. Consequence of emergence of chloroquine-resistant Plasmodium falciparum.
Topics: Age Factors; Child; Child, Preschool; Chloroquine; Drug Resistance; Emergency Service, Hospital; Hos | 1993 |
Malaria among United States troops in Somalia.
Topics: Anti-Bacterial Agents; Antimalarials; Chemoprevention; Chloroquine; Clothing; Cohort Studies; Doxycy | 1996 |
A case of vivax malaria presenting with psychosis.
Topics: Adult; Antimalarials; Chloroquine; Humans; Malaria, Cerebral; Malaria, Vivax; Male; Neurocognitive D | 1996 |
Upregulation of reactive oxygen and nitrogen intermediates in Plasmodium berghei infected mice after rescue therapy with chloroquine or artemether.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Enzyme Induction; Female; Genetic Cod | 1996 |
Chloroquine self-treatment and clinical outcome of cerebral malaria in children.
Topics: Adolescent; Animals; Cameroon; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Follow | 1997 |
Plasmodium falciparum chloroquine and quinine sensitivity in asymptomatic and symptomatic children in São Tomé Island.
Topics: Adolescent; Animals; Antimalarials; Atlantic Islands; Child; Child, Preschool; Chloroquine; Drug Res | 1997 |
Chronic cerebral malaria--is there such a clinical entity?
Topics: Antimalarials; Chloroquine; Chronic Disease; Diabetes Complications; Diabetic Coma; Humans; Malaria, | 1995 |
Rapid reemergence of T cells into peripheral circulation following treatment of severe and uncomplicated Plasmodium falciparum malaria.
Topics: Anemia; Blood Circulation; CD3 Complex; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positi | 1997 |
Resistance of Plasmodium falciparum malaria to amodiaquine, chloroquine and quinine in the Madang Province of Papua New Guinea, 1990-1993.
Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Case-Control Studies; Child; Child, Preschool; C | 1996 |
[Malaria in an urban environment: the case of the city of Rufisque in Senegal].
Topics: Adolescent; Adult; Aged; Antimalarials; Child; Chloroquine; Drug Resistance; Female; Humans; Inciden | 1997 |
A case of fever, confusion and anaemia in a young woman.
Topics: Adult; Anemia; Antimalarials; Chloroquine; Confusion; Drug Therapy, Combination; Female; Fever; Huma | 1999 |
Chloroquine-resistant Plasmodium falciparum cerebral malaria in a chloroquine-susceptible area.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Child; Child, Preschool; Chloroq | 1999 |
[Fatal cerebral malaria caused by Plasmodium falciparum after treatment with exchange transfusion].
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance; Exchange Transfusion, Whole Blood; Huma | 2000 |
Malaria--general management as recommended by WHO.
Topics: Adult; Antimalarials; Child; Chloroquine; Drug Resistance; Humans; Malaria; Malaria, Cerebral; Malar | 1992 |
[Treatment of malaria in children in France].
Topics: Antimalarials; Child; Chloroquine; France; Humans; Malaria, Cerebral; Malaria, Falciparum; Mefloquin | 1992 |
Chloroquine and proguanil prophylaxis in travellers to Kenya.
Topics: Chloroquine; Ghana; Humans; Kenya; Malaria, Cerebral; Male; Middle Aged; Patient Compliance; Proguan | 1992 |
Extrapyramidal syndrome in cerebral malaria.
Topics: Animals; Basal Ganglia Diseases; Chloroquine; Humans; Malaria, Cerebral; Malaria, Vivax; Male; Middl | 1992 |
Pathology of falciparum malaria in Vietnam.
Topics: Adult; Aged; Aged, 80 and over; Brain; Chloroquine; Female; Humans; Malaria, Cerebral; Malaria, Falc | 1992 |
Severe falciparum malaria (21 cases).
Topics: Adolescent; Adult; Child, Preschool; Chloroquine; Exchange Transfusion, Whole Blood; Female; Humans; | 1991 |
Pediatric cerebral malaria in Accra, Ghana.
Topics: Child; Child, Preschool; Chloroquine; Coma; Consciousness; Female; Ghana; Glasgow Coma Scale; Humans | 1992 |