chloroquine has been researched along with Central Nervous System Neoplasms in 4 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Central Nervous System Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arginine deprivation, either by nutritional starvation or exposure to ADI-PEG20, induces adaptive transcriptional upregulation of ASS1 and ASL in glioblastoma multiforme ex vivo cultures and cell lines." | 3.79 | Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma. ( Awad, M; Bomalaski, J; Coley, HM; Crook, T; Hatzimichael, E; Janczar, K; Langer, J; Lattanzio, L; Lo Nigro, C; O'Neil, K; Roncaroli, F; Singh, P; Syed, N; Szlosarek, P, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mulcahy Levy, JM | 1 |
| Foreman, NK | 1 |
| Thorburn, A | 1 |
| Turno-Kręcicka, A | 1 |
| Tomczyk-Socha, M | 1 |
| Zimny, A | 1 |
| Munshi, A | 1 |
| Syed, N | 1 |
| Langer, J | 1 |
| Janczar, K | 1 |
| Singh, P | 1 |
| Lo Nigro, C | 1 |
| Lattanzio, L | 1 |
| Coley, HM | 1 |
| Hatzimichael, E | 1 |
| Bomalaski, J | 1 |
| Szlosarek, P | 1 |
| Awad, M | 1 |
| O'Neil, K | 1 |
| Roncaroli, F | 1 |
| Crook, T | 1 |
1 review available for chloroquine and Central Nervous System Neoplasms
| Article | Year |
|---|---|
Chloroquine in glioblastoma--new horizons for an old drug.
Topics: Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Chloroquine; Clinical Trials as Topic; Gli | 2009 |
3 other studies available for chloroquine and Central Nervous System Neoplasms
| Article | Year |
|---|---|
Using BRAF(V600E) as a marker of autophagy dependence in pediatric brain tumors.
Topics: Antineoplastic Agents; Autophagy; Brain Neoplasms; Brain Stem; Central Nervous System Neoplasms; Chi | 2014 |
Progressive outer retinal necrosis syndrome in the course of systemic lupus erythematosus.
Topics: Adult; Antiviral Agents; Central Nervous System Neoplasms; Chloroquine; Chorioretinitis; Fatal Outco | 2016 |
Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma.
Topics: Apoptosis; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Autophagy; Azacitidine; Ce | 2013 |