chloroquine has been researched along with Cell Transformation, Viral in 14 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Cell Transformation, Viral: An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Addition of 10 mM NH4C1 to the medium inhibited viral growth by greater than 80% and reduced toxic effects of the virus on cell viability, protein, and DNA synthesis by 30-45%." | 1.27 | Ammonium inhibits processing and cytotoxicity of reovirus, a nonenveloped virus. ( Goodman, MJ; Kahn, CR; Maratos-Flier, E; Murray, AH, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (71.43) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franck, X | 1 |
| Fournet, A | 1 |
| Prina, E | 1 |
| Mahieux, R | 1 |
| Hocquemiller, R | 1 |
| Figadère, B | 1 |
| Chu, E | 1 |
| Umetsu, D | 1 |
| Lareau, M | 1 |
| Schneeberger, E | 1 |
| Geha, RS | 1 |
| Seth, P | 1 |
| Willingham, MC | 1 |
| Pastan, I | 1 |
| Talbot, PJ | 1 |
| Vance, DE | 1 |
| Inagaki, M | 1 |
| Katsumoto, T | 1 |
| Nanba, E | 1 |
| Ohno, K | 1 |
| Suehiro, S | 1 |
| Takeshita, K | 1 |
| Wu, JD | 1 |
| Butler, J | 1 |
| Bailey, JM | 1 |
| Wilson, CA | 1 |
| Marsh, JW | 1 |
| Eiden, MV | 1 |
| Gromeier, M | 1 |
| Wetz, K | 1 |
| Cowley, GP | 1 |
| Smith, JA | 1 |
| Gusterson, BA | 1 |
| Kuge, O | 1 |
| Akamatsu, Y | 1 |
| Nishijima, M | 1 |
| Tooze, J | 1 |
| Tooze, SA | 1 |
| Fuller, SD | 1 |
| Upcroft, P | 1 |
| Lombardi, G | 1 |
| del Gallo, F | 1 |
| Vismara, D | 1 |
| Piccolella, E | 1 |
| de Martino, C | 1 |
| Garzelli, C | 1 |
| Puglisi, C | 1 |
| Colizzi, V | 1 |
| Maratos-Flier, E | 1 |
| Goodman, MJ | 1 |
| Murray, AH | 1 |
| Kahn, CR | 1 |
14 other studies available for chloroquine and Cell Transformation, Viral
| Article | Year |
|---|---|
Biological evaluation of substituted quinolines.
Topics: Animals; Antiparasitic Agents; Cell Line; Cell Transformation, Viral; Evaluation Studies as Topic; H | 2004 |
Analysis of antigen uptake and presentation by Epstein-Barr virus-transformed human lymphoblastoid B cells.
Topics: Azides; B-Lymphocytes; Cell Transformation, Viral; Chloroquine; Clone Cells; Deoxyglucose; Diphtheri | 1984 |
Adenovirus-dependent release of 51Cr from KB cells at an acidic pH.
Topics: Adenoviruses, Human; ADP Ribose Transferases; Bacterial Toxins; Carcinoma; Cell Transformation, Vira | 1984 |
Evidence that Sindbis virus infects BHK-21 cells via a lysosomal route.
Topics: Ammonium Chloride; Animals; Cell Line; Cell Transformation, Viral; Chloroquine; Cricetinae; Kidney; | 1980 |
Lysosomal glycosphingolipid storage in chloroquine-induced alpha-galactosidase-deficient human endothelial cells with transformation by simian virus 40: in vitro model of Fabry disease.
Topics: Cell Transformation, Viral; Chloroquine; Clomipramine; Endothelium, Vascular; Fabry Disease; Galacto | 1993 |
Lipid metabolism in cultured cells. XVIII. Comparative uptake of low density and high density lipoproteins by normal, hypercholesterolemic and tumor virus-transformed human fibroblasts.
Topics: Animals; Biological Transport; Cell Line; Cell Transformation, Viral; Chloroquine; Cycloheximide; He | 1979 |
The requirements for viral entry differ from those for virally induced syncytium formation in NIH 3T3/DTras cells exposed to Moloney murine leukemia virus.
Topics: 3T3 Cells; Animals; Cell Line; Cell Transformation, Viral; Chiroptera; Chloroquine; Giant Cells; Hum | 1992 |
Kinetics of poliovirus uncoating in HeLa cells in a nonacidic environment.
Topics: Ammonium Chloride; Cell Transformation, Viral; Chloroquine; Endocytosis; Glutathione; HeLa Cells; Ho | 1990 |
Increased EGF receptors on human squamous carcinoma cell lines.
Topics: Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Viral; Chloroquine; Chromatography, High P | 1986 |
Abortive infection with Sindbis virus of a Chinese hamster ovary cell mutant defective in phosphatidylserine and phosphatidylethanolamine biosynthesis.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Viral; Chloroquine; Cricetinae; Cricetulus; | 1989 |
Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells.
Topics: Adrenocorticotropic Hormone; Animals; Cell Line; Cell Transformation, Viral; Chloroquine; DNA Replic | 1987 |
Simian virus 40 infection is not mediated by lysosomal activation.
Topics: Ammonium Chloride; Cell Line; Cell Transformation, Viral; Chloroquine; Lysosomes; Simian virus 40; V | 1987 |
Epstein-Barr virus-transformed B cells process and present Mycobacterium tuberculosis particulate antigens to T-cell clones.
Topics: Antigen-Presenting Cells; Antigens, Bacterial; B-Lymphocytes; Cell Transformation, Viral; Chloroquin | 1987 |
Ammonium inhibits processing and cytotoxicity of reovirus, a nonenveloped virus.
Topics: Ammonia; Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Viral; Chloroquine; | 1986 |