chloroquine has been researched along with Cataract in 25 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic treatment of rats with the amphipilic drugs chloroquine and chlorphentermine caused prominent anterior polar cataracts in virtually all rats." | 7.66 | Anterior polar cataract and lysosomal alterations in the lens of rats treated with the amphiphilic lipidosis-inducing drugs chloroquine and chlorphentermine. ( Drenckhahn, D, 1978) |
| "Chronic treatment of rats with the amphipilic drugs chloroquine and chlorphentermine caused prominent anterior polar cataracts in virtually all rats." | 3.66 | Anterior polar cataract and lysosomal alterations in the lens of rats treated with the amphiphilic lipidosis-inducing drugs chloroquine and chlorphentermine. ( Drenckhahn, D, 1978) |
| "Mean intraocular pressure was 12 mmHg (standard deviation, 4." | 1.35 | Ocular manifestation in treated multibacillary Hansen's disease. ( Muliyil, J; Parikh, R; Parikh, S; Thomas, R; Thomas, S, 2009) |
| "Surgical treatment of cataracts, band keratopathy, and glaucoma achieved uniformly discouraging results." | 1.25 | Ocular manifestations of juvenile rheumatoid arthritis. ( Bellows, AR; Bienfang, DC; Chylack, LT; Stillman, JS, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (92.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, X | 1 |
| Zhao, X | 1 |
| Cheng, R | 1 |
| Huang, Y | 1 |
| Parikh, R | 1 |
| Thomas, S | 1 |
| Muliyil, J | 1 |
| Parikh, S | 1 |
| Thomas, R | 1 |
| SANDVIG, K | 1 |
| HAVRE, DC | 1 |
| Stewart, AJ | 1 |
| Hill, RH | 1 |
| Drenckhahn, D | 2 |
| Davidson, S | 1 |
| Lüllmann-Rauch, R | 1 |
| Crews, SJ | 1 |
| Chylack, LT | 1 |
| Bienfang, DC | 1 |
| Bellows, AR | 1 |
| Stillman, JS | 1 |
| Trojan, HJ | 1 |
| Böke, W | 1 |
| Boden, BF | 1 |
| Koch, HR | 1 |
| Hockwin, O | 1 |
| Casanovas, J | 1 |
| Casanovas, R | 1 |
| Barg, TsM | 1 |
| Lal, S | 1 |
| Gupta, AK | 1 |
| Lakowski, R | 1 |
| Kelsey, JH | 1 |
| Edwards, A | 1 |
| Gupta, JD | 1 |
| Harley, JD | 1 |
| Smiley, WK | 1 |
| Bernstein, HN | 2 |
| Nowicki, NJ | 1 |
| Bihari, M | 1 |
| Grossman, BJ | 1 |
| Goren, SB | 1 |
5 reviews available for chloroquine and Cataract
| Article | Year |
|---|---|
[Eye complications during use of various medicinal substances with general effects (review of the literature)].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Anti-Bacterial Agents; Antimalari | 1969 |
Ocular complications in rheumatic disorders.
Topics: Arthritis, Rheumatoid; Cataract; Chloroquine; Conjunctivitis; Eye Diseases; Glaucoma; Humans; Iritis | 1973 |
The eye in arthritis.
Topics: Adrenal Cortex Hormones; Adult; Antimalarials; Arthritis; Arthritis, Juvenile; Arthritis, Reactive; | 1969 |
Some iatrogenic ocular diseases from systemically administered drugs.
Topics: Animals; Cataract; Cats; Chemical Phenomena; Chemistry; Chloramphenicol; Chloroquine; Chlorpromazine | 1970 |
Chloroquine ocular toxicity.
Topics: Animals; Binding Sites; Cataract; Cats; Chloroquine; Ciliary Body; Cornea; Electrooculography; Elect | 1967 |
20 other studies available for chloroquine and Cataract
| Article | Year |
|---|---|
Autophagy attenuates high glucose-induced oxidative injury to lens epithelial cells.
Topics: Animals; Autophagy; Cataract; Cells, Cultured; Chloroquine; Culture Media; Diabetes Mellitus, Experi | 2020 |
Ocular manifestation in treated multibacillary Hansen's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blindness; Cataract; Child; Chloroquine; Corneal Disease | 2009 |
CORNEAL CHANGES DURING CHLOROQUINE TREATMENT. AN INVESTIGATION OF 70 PATIENTS WITH CHRONIC RHEUMATOID ARTHRITIS RECEIVING CHLOROQUINE TREATMENT.
Topics: Arthritis, Rheumatoid; Cataract; Chloroquine; Cornea; Glaucoma; Humans; Pathology; Toxicology | 1963 |
CATARACTS IN CHILDREN ON LONG-TERM CORTICOSTEROID THERAPY.
Topics: Adolescent; Adrenal Cortex Hormones; Cataract; Child; Chloroquine; Cyclophosphamide; Drug Therapy; F | 1965 |
Ocular manifestations in juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Arthritis, Juvenile; Cataract; Child; Child, Preschool; Chloroquine; Cornea; Cort | 1967 |
Anterior polar cataract and lysosomal alterations in the lens of rats treated with the amphiphilic lipidosis-inducing drugs chloroquine and chlorphentermine.
Topics: Acid Phosphatase; Animals; Cataract; Chloroquine; Chlorphentermine; Epithelium; Female; Inclusion Bo | 1978 |
General medicine and visual side effects.
Topics: Cataract; Chloroquine; Cyclopentolate; Eye Diseases; Glaucoma; Humans; Prednisone | 1979 |
Lens opacities associated with lipidosis-like ultrastructural alterations in rats treated with chloroquine, chlorphentermine, or iprindole.
Topics: Animals; Cataract; Chloroquine; Chlorphentermine; Cytoplasm; Epithelial Cells; Epithelium; Female; I | 1977 |
Ocular adverse reactions to drugs.
Topics: Adrenal Cortex Hormones; Adult; Aged; Amblyopia; Cataract; Chloroquine; Chlorpromazine; Conjunctivit | 1977 |
Ocular manifestations of juvenile rheumatoid arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Arthritis, Juvenile; Atropine; Cataract; Ch | 1975 |
[Eye complications in the long-term treatment with chloroquin. Study carried out in Togo].
Topics: Cataract; Chloroquine; Corneal Opacity; Eye Diseases; Female; Humans; Macular Degeneration; Malaria; | 1975 |
[Eye findings in rheumatic diseases].
Topics: Adolescent; Arthritis, Juvenile; Arthritis, Reactive; Arthritis, Rheumatoid; Behcet Syndrome; Catara | 1974 |
[Iatrogenic cataracts].
Topics: Aged; Anesthetics, Local; Anthelmintics; Azathioprine; Cataract; Chloroquine; Chlorpromazine; Dimeth | 1974 |
[Ocular manifestations in rheumatic diseases (new contributions)].
Topics: Adrenal Cortex Hormones; Aged; Alkaptonuria; Arthritis, Juvenile; Arthritis, Rheumatoid; Behcet Synd | 1970 |
Lenticular deposits associated with chloroquine Keratopathy.
Topics: Cataract; Chloroquine; Corneal Opacity; Humans; Leprosy; Male; Middle Aged | 1974 |
The Pickford-Nicolson anomaloscope as a test for acquired dyschromatopsias.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Cataract; Cataract Extraction; Child; Chloroquine; C | 1972 |
Photomicrographic evaluation of drug-induced cataracts in cultured embryonic chick lens.
Topics: Animals; Cataract; Chick Embryo; Chloroquine; Culture Media; Culture Techniques; Hydroquinones; Lens | 1973 |
Interrelationships of ophthalmology and rheumatic diseases.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Cataract; Chloroquine; Eye Diseases; Glaucoma; Human | 1968 |
Posterior subcapsular cataracts. Related to long-term corticosteroid treatment in children.
Topics: Adolescent; Arthritis, Juvenile; Cataract; Child; Child, Preschool; Chloroquine; Colitis, Ulcerative | 1968 |
Ocular toxicity of commonly used systemic drugs.
Topics: Adrenal Cortex Hormones; Cardiac Glycosides; Cataract; Chloroquine; Contraceptives, Oral; Eye Diseas | 1969 |