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chloroquine and Cataract

chloroquine has been researched along with Cataract in 25 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Chronic treatment of rats with the amphipilic drugs chloroquine and chlorphentermine caused prominent anterior polar cataracts in virtually all rats."7.66Anterior polar cataract and lysosomal alterations in the lens of rats treated with the amphiphilic lipidosis-inducing drugs chloroquine and chlorphentermine. ( Drenckhahn, D, 1978)
"Chronic treatment of rats with the amphipilic drugs chloroquine and chlorphentermine caused prominent anterior polar cataracts in virtually all rats."3.66Anterior polar cataract and lysosomal alterations in the lens of rats treated with the amphiphilic lipidosis-inducing drugs chloroquine and chlorphentermine. ( Drenckhahn, D, 1978)
"Mean intraocular pressure was 12 mmHg (standard deviation, 4."1.35Ocular manifestation in treated multibacillary Hansen's disease. ( Muliyil, J; Parikh, R; Parikh, S; Thomas, R; Thomas, S, 2009)
"Surgical treatment of cataracts, band keratopathy, and glaucoma achieved uniformly discouraging results."1.25Ocular manifestations of juvenile rheumatoid arthritis. ( Bellows, AR; Bienfang, DC; Chylack, LT; Stillman, JS, 1975)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199023 (92.00)18.7374
1990's0 (0.00)18.2507
2000's1 (4.00)29.6817
2010's0 (0.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Liu, X1
Zhao, X1
Cheng, R1
Huang, Y1
Parikh, R1
Thomas, S1
Muliyil, J1
Parikh, S1
Thomas, R1
SANDVIG, K1
HAVRE, DC1
Stewart, AJ1
Hill, RH1
Drenckhahn, D2
Davidson, S1
Lüllmann-Rauch, R1
Crews, SJ1
Chylack, LT1
Bienfang, DC1
Bellows, AR1
Stillman, JS1
Trojan, HJ1
Böke, W1
Boden, BF1
Koch, HR1
Hockwin, O1
Casanovas, J1
Casanovas, R1
Barg, TsM1
Lal, S1
Gupta, AK1
Lakowski, R1
Kelsey, JH1
Edwards, A1
Gupta, JD1
Harley, JD1
Smiley, WK1
Bernstein, HN2
Nowicki, NJ1
Bihari, M1
Grossman, BJ1
Goren, SB1

Reviews

5 reviews available for chloroquine and Cataract

ArticleYear
[Eye complications during use of various medicinal substances with general effects (review of the literature)].
    Oftalmologicheskii zhurnal, 1969, Volume: 24, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Anti-Bacterial Agents; Antimalari

1969
Ocular complications in rheumatic disorders.
    Rheumatology and rehabilitation, 1973, Volume: 12, Issue:1

    Topics: Arthritis, Rheumatoid; Cataract; Chloroquine; Conjunctivitis; Eye Diseases; Glaucoma; Humans; Iritis

1973
The eye in arthritis.
    Annals of physical medicine, 1969, Volume: 10, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Antimalarials; Arthritis; Arthritis, Juvenile; Arthritis, Reactive;

1969
Some iatrogenic ocular diseases from systemically administered drugs.
    International ophthalmology clinics, 1970,Fall, Volume: 10, Issue:3

    Topics: Animals; Cataract; Cats; Chemical Phenomena; Chemistry; Chloramphenicol; Chloroquine; Chlorpromazine

1970
Chloroquine ocular toxicity.
    Survey of ophthalmology, 1967, Volume: 12, Issue:5

    Topics: Animals; Binding Sites; Cataract; Cats; Chloroquine; Ciliary Body; Cornea; Electrooculography; Elect

1967

Other Studies

20 other studies available for chloroquine and Cataract

ArticleYear
Autophagy attenuates high glucose-induced oxidative injury to lens epithelial cells.
    Bioscience reports, 2020, 04-30, Volume: 40, Issue:4

    Topics: Animals; Autophagy; Cataract; Cells, Cultured; Chloroquine; Culture Media; Diabetes Mellitus, Experi

2020
Ocular manifestation in treated multibacillary Hansen's disease.
    Ophthalmology, 2009, Volume: 116, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blindness; Cataract; Child; Chloroquine; Corneal Disease

2009
CORNEAL CHANGES DURING CHLOROQUINE TREATMENT. AN INVESTIGATION OF 70 PATIENTS WITH CHRONIC RHEUMATOID ARTHRITIS RECEIVING CHLOROQUINE TREATMENT.
    Acta rheumatologica Scandinavica, 1963, Volume: 9

    Topics: Arthritis, Rheumatoid; Cataract; Chloroquine; Cornea; Glaucoma; Humans; Pathology; Toxicology

1963
CATARACTS IN CHILDREN ON LONG-TERM CORTICOSTEROID THERAPY.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1965, Volume: 73

    Topics: Adolescent; Adrenal Cortex Hormones; Cataract; Child; Chloroquine; Cyclophosphamide; Drug Therapy; F

1965
Ocular manifestations in juvenile rheumatoid arthritis.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1967, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Arthritis, Juvenile; Cataract; Child; Child, Preschool; Chloroquine; Cornea; Cort

1967
Anterior polar cataract and lysosomal alterations in the lens of rats treated with the amphiphilic lipidosis-inducing drugs chloroquine and chlorphentermine.
    Virchows Archiv. B, Cell pathology, 1978, May-19, Volume: 27, Issue:3

    Topics: Acid Phosphatase; Animals; Cataract; Chloroquine; Chlorphentermine; Epithelium; Female; Inclusion Bo

1978
General medicine and visual side effects.
    British medical journal, 1979, Mar-24, Volume: 1, Issue:6166

    Topics: Cataract; Chloroquine; Cyclopentolate; Eye Diseases; Glaucoma; Humans; Prednisone

1979
Lens opacities associated with lipidosis-like ultrastructural alterations in rats treated with chloroquine, chlorphentermine, or iprindole.
    Experimental eye research, 1977, Volume: 24, Issue:6

    Topics: Animals; Cataract; Chloroquine; Chlorphentermine; Cytoplasm; Epithelial Cells; Epithelium; Female; I

1977
Ocular adverse reactions to drugs.
    The Practitioner, 1977, Volume: 219, Issue:1309

    Topics: Adrenal Cortex Hormones; Adult; Aged; Amblyopia; Cataract; Chloroquine; Chlorpromazine; Conjunctivit

1977
Ocular manifestations of juvenile rheumatoid arthritis.
    American journal of ophthalmology, 1975, Volume: 79, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Arthritis, Juvenile; Atropine; Cataract; Ch

1975
[Eye complications in the long-term treatment with chloroquin. Study carried out in Togo].
    Revue internationale du trachome et de pathologie oculaire tropicale et subtropicale : organe de la Ligue contre le trachome avec la collaboration de l'International Organization against Trachoma et des organisations nationales et inter..., 1975, Volume: 52, Issue:3-4

    Topics: Cataract; Chloroquine; Corneal Opacity; Eye Diseases; Female; Humans; Macular Degeneration; Malaria;

1975
[Eye findings in rheumatic diseases].
    Der Internist, 1974, Volume: 15, Issue:10

    Topics: Adolescent; Arthritis, Juvenile; Arthritis, Reactive; Arthritis, Rheumatoid; Behcet Syndrome; Catara

1974
[Iatrogenic cataracts].
    Medizinische Klinik, 1974, Oct-18, Volume: 69, Issue:42

    Topics: Aged; Anesthetics, Local; Anthelmintics; Azathioprine; Cataract; Chloroquine; Chlorpromazine; Dimeth

1974
[Ocular manifestations in rheumatic diseases (new contributions)].
    Archives d'ophtalmologie et revue generale d'ophtalmologie, 1970, Volume: 30, Issue:12

    Topics: Adrenal Cortex Hormones; Aged; Alkaptonuria; Arthritis, Juvenile; Arthritis, Rheumatoid; Behcet Synd

1970
Lenticular deposits associated with chloroquine Keratopathy.
    Indian journal of ophthalmology, 1974, Volume: 22, Issue:2

    Topics: Cataract; Chloroquine; Corneal Opacity; Humans; Leprosy; Male; Middle Aged

1974
The Pickford-Nicolson anomaloscope as a test for acquired dyschromatopsias.
    Modern problems in ophthalmology, 1972, Volume: 11

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Cataract; Cataract Extraction; Child; Chloroquine; C

1972
Photomicrographic evaluation of drug-induced cataracts in cultured embryonic chick lens.
    Experimental eye research, 1973, Volume: 15, Issue:4

    Topics: Animals; Cataract; Chick Embryo; Chloroquine; Culture Media; Culture Techniques; Hydroquinones; Lens

1973
Interrelationships of ophthalmology and rheumatic diseases.
    Journal of the American Geriatrics Society, 1968, Volume: 16, Issue:5

    Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Cataract; Chloroquine; Eye Diseases; Glaucoma; Human

1968
Posterior subcapsular cataracts. Related to long-term corticosteroid treatment in children.
    American journal of diseases of children (1960), 1968, Volume: 116, Issue:6

    Topics: Adolescent; Arthritis, Juvenile; Cataract; Child; Child, Preschool; Chloroquine; Colitis, Ulcerative

1968
Ocular toxicity of commonly used systemic drugs.
    Postgraduate medicine, 1969, Volume: 45, Issue:5

    Topics: Adrenal Cortex Hormones; Cardiac Glycosides; Cataract; Chloroquine; Contraceptives, Oral; Eye Diseas

1969