chloroquine has been researched along with Cardiovascular Stroke in 13 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zacopride (15 µg/kg) was administered (intraperitoneally) daily for 28 days after MI to determine whether it could attenuate MI-induced cardiac remodeling." | 5.40 | Activation of IK1 channel by zacopride attenuates left ventricular remodeling in rats with myocardial infarction. ( Cao, JM; Cui, XL; Feng, QL; Liu, CF; Liu, EL; Liu, QH; Luo, TE; Wu, BW; Zhai, XW; Zhang, L; Zhang, WF; Zhao, ZQ, 2014) |
| "Treatment with vildagliptin (10 mg/kg/day s." | 1.42 | Inhibition of DPP-4 reduces acute mortality after myocardial infarction with restoration of autophagic response in type 2 diabetic rats. ( Ishikawa, S; Kouzu, H; Kuno, A; Miki, T; Miura, T; Murase, H; Nishizawa, K; Ogasawara, M; Tanno, M; Tobisawa, T; Yano, T, 2015) |
| "Zacopride (15 µg/kg) was administered (intraperitoneally) daily for 28 days after MI to determine whether it could attenuate MI-induced cardiac remodeling." | 1.40 | Activation of IK1 channel by zacopride attenuates left ventricular remodeling in rats with myocardial infarction. ( Cao, JM; Cui, XL; Feng, QL; Liu, CF; Liu, EL; Liu, QH; Luo, TE; Wu, BW; Zhai, XW; Zhang, L; Zhang, WF; Zhao, ZQ, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, L | 1 |
| Zhang, W | 1 |
| Xie, L | 1 |
| Liu, S | 1 |
| Cheng, J | 1 |
| Wang, L | 1 |
| Liu, J | 1 |
| Gong, J | 1 |
| Liu, CF | 1 |
| Liu, QH | 1 |
| Liu, EL | 1 |
| Zhai, XW | 1 |
| Zhang, L | 1 |
| Luo, TE | 1 |
| Zhang, WF | 1 |
| Feng, QL | 1 |
| Cui, XL | 1 |
| Zhao, ZQ | 1 |
| Cao, JM | 1 |
| Wu, BW | 1 |
| Murase, H | 1 |
| Kuno, A | 1 |
| Miki, T | 1 |
| Tanno, M | 1 |
| Yano, T | 1 |
| Kouzu, H | 1 |
| Ishikawa, S | 1 |
| Tobisawa, T | 1 |
| Ogasawara, M | 1 |
| Nishizawa, K | 1 |
| Miura, T | 1 |
| Zhang, J | 1 |
| Nadtochiy, SM | 1 |
| Urciuoli, WR | 1 |
| Brookes, PS | 1 |
| CELICE, J | 1 |
| PLAS, F | 1 |
| Meerson, FZ | 1 |
| Dosmagambetova, RS | 1 |
| Horrobin, DF | 1 |
| Karmazyn, M | 1 |
| Ally, A | 1 |
| Swift, A | 1 |
| Manku, MS | 1 |
| Morgan, RO | 1 |
| Karmali, RA | 1 |
| Friedman, G | 1 |
| Stein, O | 1 |
| Halperin, G | 1 |
| Kimchi, A | 1 |
| Stein, Y | 1 |
| Dzizinskiĭ, AA | 2 |
| Katiubin, VP | 2 |
| Moccetti, T | 1 |
| Malhotra, V | 1 |
| Krishan, I | 1 |
1 trial available for chloroquine and Cardiovascular Stroke
| Article | Year |
|---|---|
[Effects of antioxidants and membrane protectors on clinical course and hemodynamics of patients with myocardial infarct].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Chloroquine; Female; Humans; Male; Middle Age | 1992 |
12 other studies available for chloroquine and Cardiovascular Stroke
| Article | Year |
|---|---|
Preconditioning of mesenchymal stem cells with ghrelin exerts superior cardioprotection in aged heart through boosting mitochondrial function and autophagy flux.
Topics: Aged; Animals; Autophagy; Beclin-1; Cardiotonic Agents; Chloroquine; Drug Synergism; Ghrelin; Humans | 2021 |
Exogenous administration of mitochondrial DNA promotes ischemia reperfusion injury via TLR9-p38 MAPK pathway.
Topics: Animals; Antimalarials; Caspase 3; Cell Line; Chloroquine; DNA, Mitochondrial; In Situ Nick-End Labe | 2017 |
Activation of IK1 channel by zacopride attenuates left ventricular remodeling in rats with myocardial infarction.
Topics: Animals; Anti-Arrhythmia Agents; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Chloroquine; E | 2014 |
Inhibition of DPP-4 reduces acute mortality after myocardial infarction with restoration of autophagic response in type 2 diabetic rats.
Topics: Adamantane; Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Chloroquine; Diabetes Melli | 2015 |
The cardioprotective compound cloxyquin uncouples mitochondria and induces autophagy.
Topics: Animals; Autophagy; Chloroquine; Chloroquinolinols; Dose-Response Relationship, Drug; Green Fluoresc | 2016 |
[Improvement of a case of primary malaria with signs of myocardial infarct after nivaquine therapy].
Topics: Chloroquine; Malaria; Myocardial Infarction; Quinolines | 1956 |
[Disorder of the contractile function of the nonischemic portion of the heart in experimental infarct and its prevention by the phospholipase inhibitor chloroquine].
Topics: Animals; Chloroquine; Drug Evaluation, Preclinical; Enzyme Activation; In Vitro Techniques; Male; My | 1983 |
Platelets, lipids, and myocardial infarction.
Topics: Aspirin; Chloroquine; Fatty Acids, Unsaturated; Humans; Myocardial Infarction; Prostaglandin Antagon | 1977 |
Study of cultured skin fibroblasts from patients with and without ischemic heart disease. Metabolism of low density lipoprotein and cholesterol ester, synthesis of cellular lipids and effect of chloroquine on accumulation of cholesterol ester.
Topics: Adult; Cells, Cultured; Chloroquine; Cholesterol; Cholesterol Esters; Coronary Disease; Fibroblasts; | 1978 |
[Clinical course and necrotic area size in patients with myocardial infarct receiving combined treatment including antioxidants and membrane-protecting agents].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chloroquine; Drug Therapy, Combination; Female; Humans; Mal | 1991 |
[Cardiotoxic drugs].
Topics: Adult; Angina Pectoris; Anti-Bacterial Agents; Antipsychotic Agents; Chloroquine; Contraceptives, Or | 1973 |
Resistant ventricular tachycardia responsive to chloroquine.
Topics: Chloroquine; Humans; Male; Middle Aged; Myocardial Infarction; Procainamide; Quinidine; Tachycardia, | 1968 |