chloroquine has been researched along with Cardiac Failure in 17 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We found no increased risk of ischemic heart injury or heart failure as a result of administering chloroquine." | 8.02 | No difference in biomarkers of ischemic heart injury and heart failure in patients with COVID-19 who received treatment with chloroquine phosphate and those who did not. ( Beck-Friis, J; Gisslen, M; Leach, S; Omerovic, E; Yilmaz, A; Zeijlon, R, 2021) |
| " We describe a patient with recurrent malaria, prophylactically treated with low-dose chloroquine, who developed heart failure due to biventricular cardiac dysfunction." | 7.75 | Cardiotoxicity after low-dose chloroquine antimalarial therapy. ( Baratto, F; Doglioni, C; Fragasso, G; Margonato, A; Martinenghi, S; Sanvito, F, 2009) |
| " Although, most adverse cardiac events related to HCQ/CQ usage in COVID-19 were secondary to conduction disorders given the short duration of treatment, HCQ/CQ can cause CM and HF, with chronic usage." | 6.82 | Review of Hydroxychloroquine Cardiotoxicity: Lessons From the COVID-19 Pandemic. ( Gagnon, LR; Oudit, GY; Sadasivan, C; Yogasundaram, H, 2022) |
| " In fact, two of the actually used drugs against SARS-CoV2, such as chloroquine and the combination lopinavir/ritonavir, might determine a QT (the time from the start of the Q wave to the end of the T wave) interval prolongation and they show several interactions with antiarrhythmic drugs and antipsychotic medications, making them prone to an increased risk of developing arrhythmias." | 5.12 | COVID-19 and the burning issue of drug interaction: never forget the ECG. ( Cameli, M; Cameli, P; Franchi, F; Mandoli, GE; Menci, D; Mondillo, S; Sciaccaluga, C; Sisti, N; Valente, S, 2021) |
| "A 58 year old woman on long term treatment with chloroquine for systemic lupus erythematosus presented with cardiac conduction disorders and heart failure with hypertrophic cardiomyopathy, which was confirmed by histology to be related to chloroquine toxicity." | 4.80 | Chloroquine cardiomyopathy with conduction disorders. ( Baguet, JP; Fabre, M; Tremel, F, 1999) |
| "We found no increased risk of ischemic heart injury or heart failure as a result of administering chloroquine." | 4.02 | No difference in biomarkers of ischemic heart injury and heart failure in patients with COVID-19 who received treatment with chloroquine phosphate and those who did not. ( Beck-Friis, J; Gisslen, M; Leach, S; Omerovic, E; Yilmaz, A; Zeijlon, R, 2021) |
| " We describe a patient with recurrent malaria, prophylactically treated with low-dose chloroquine, who developed heart failure due to biventricular cardiac dysfunction." | 3.75 | Cardiotoxicity after low-dose chloroquine antimalarial therapy. ( Baratto, F; Doglioni, C; Fragasso, G; Margonato, A; Martinenghi, S; Sanvito, F, 2009) |
| " Although, most adverse cardiac events related to HCQ/CQ usage in COVID-19 were secondary to conduction disorders given the short duration of treatment, HCQ/CQ can cause CM and HF, with chronic usage." | 2.82 | Review of Hydroxychloroquine Cardiotoxicity: Lessons From the COVID-19 Pandemic. ( Gagnon, LR; Oudit, GY; Sadasivan, C; Yogasundaram, H, 2022) |
| "Laboratory investigation indicated disseminated intravascular coagulation confirmed by petechial hemorrhages in the leptomeninges at autopsy, a finding that has not previously been described." | 1.29 | Suicidal chloroquine poisoning: clinical course, autopsy findings, and chemical analysis. ( Bauer, G; Berzlanovich, A; Binder, R; Laggner, AN; Malzer, R; Mortinger, H; Muhm, M; Stimpfl, T; Vycudilik, W, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 5 (29.41) | 2.80 |
| Authors | Studies |
|---|---|
| Gagnon, LR | 1 |
| Sadasivan, C | 1 |
| Yogasundaram, H | 2 |
| Oudit, GY | 2 |
| Sciaccaluga, C | 1 |
| Cameli, M | 1 |
| Menci, D | 1 |
| Mandoli, GE | 1 |
| Sisti, N | 1 |
| Cameli, P | 1 |
| Franchi, F | 1 |
| Mondillo, S | 1 |
| Valente, S | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 10 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Zhang, S | 2 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
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| Pangarah, CA | 1 |
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| Zeng, C | 2 |
| Du, H | 1 |
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| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
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| Booth, CM | 1 |
| Berry, S | 1 |
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| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
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| Zhou, L | 2 |
| Dong, X | 1 |
| Tang, S | 1 |
| Gao, XC | 1 |
| Wei, CH | 1 |
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| Cai, Q | 1 |
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| Tong, F | 1 |
| Dong, JH | 1 |
| Wu, G | 1 |
| Dong, XR | 1 |
| Tang, X | 2 |
| Tao, F | 1 |
| Xiang, W | 1 |
| Zhao, Y | 2 |
| Jin, L | 1 |
| Tao, H | 1 |
| Lei, Y | 1 |
| Gan, H | 1 |
| Huang, Y | 1 |
| Chen, Y | 3 |
| Chen, L | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
| Zhang, J | 3 |
| Li, Y | 5 |
| Xue, F | 1 |
| Deng, L | 1 |
| Liu, L | 2 |
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| Vagenende, B | 1 |
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| Liu, X | 1 |
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| Li, J | 7 |
| Li, P | 1 |
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| Meng, P | 1 |
| Wang, F | 2 |
| Wang, YS | 1 |
| Wang, C | 3 |
| Zhou, X | 2 |
| Wang, W | 1 |
| Wang, S | 2 |
| Hou, J | 1 |
| Zhang, A | 1 |
| Lv, B | 1 |
| Gao, C | 1 |
| Pang, D | 1 |
| Lu, K | 1 |
| Ahmad, NH | 1 |
| Wang, L | 1 |
| Zhu, J | 2 |
| Zhang, L | 2 |
| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 5 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
| Zhao, Q | 1 |
| Hu, W | 1 |
| Zhang, Y | 4 |
| Wu, X | 1 |
| Lu, J | 2 |
| Li, M | 1 |
| Li, W | 2 |
| Wu, W | 1 |
| Du, F | 1 |
| Ji, H | 1 |
| Yang, X | 2 |
| Xu, Z | 1 |
| Wan, L | 1 |
| Wen, Q | 1 |
| Cho, CH | 1 |
| Zou, C | 1 |
| Xiao, Z | 1 |
| Liao, J | 1 |
| Su, X | 1 |
| Bi, Z | 1 |
| Su, Q | 1 |
| Huang, H | 1 |
| Wei, Y | 2 |
| Gao, Y | 2 |
| Na, KJ | 1 |
| Choi, H | 1 |
| Oh, HR | 1 |
| Kim, YH | 1 |
| Lee, SB | 1 |
| Jung, YJ | 1 |
| Koh, J | 1 |
| Park, S | 1 |
| Lee, HJ | 1 |
| Jeon, YK | 1 |
| Chung, DH | 1 |
| Paeng, JC | 1 |
| Park, IK | 1 |
| Kang, CH | 1 |
| Cheon, GJ | 1 |
| Kang, KW | 1 |
| Lee, DS | 1 |
| Kim, YT | 1 |
| Pajuelo-Lozano, N | 1 |
| Alcalá, S | 1 |
| Sainz, B | 1 |
| Perona, R | 1 |
| Sanchez-Perez, I | 1 |
| Logotheti, S | 1 |
| Marquardt, S | 1 |
| Gupta, SK | 1 |
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| Zhang, M | 4 |
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| Yang, T | 2 |
| Dong, Y | 1 |
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| Liu, Z | 2 |
| Liang, C | 1 |
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| Yu, K | 1 |
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| Huang, Z | 1 |
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| Liu, Y | 4 |
| Mi, Y | 1 |
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| Luo, X | 1 |
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| Chang, X | 2 |
| Zhang, T | 2 |
| Wang, Q | 2 |
| Rathore, MG | 1 |
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| Shin, SH | 1 |
| Ma, WY | 1 |
| Bode, AM | 1 |
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| Liu, C | 4 |
| Gao, F | 1 |
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| Zhang, X | 5 |
| Cai, X | 1 |
| Ji, RY | 1 |
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| Tian, J | 2 |
| Shi, Y | 1 |
| Ying, S | 1 |
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| Feng, G | 1 |
| Kuang, Y | 1 |
| Chen, D | 1 |
| Wu, D | 3 |
| Zhu, ZQ | 1 |
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| Shi, ZE | 1 |
| Kang, J | 1 |
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| Qi, J | 2 |
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| Celestrin, CP | 1 |
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| Guadagnini, D | 1 |
| Tadelle, RM | 1 |
| Saad, MJA | 1 |
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| Bronzo, P | 1 |
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| Sahebkar, A | 1 |
| Mannarino, MR | 1 |
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| Patsourakos, NG | 1 |
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| Kalantzi, KI | 1 |
| Tsoumani, ME | 1 |
| Anastasiadis, F | 1 |
| Andronikos, P | 1 |
| Aslanidou, T | 1 |
| Efraimidis, P | 1 |
| Georgiopoulos, A | 1 |
| Gerakiou, K | 1 |
| Grigoriadou-Skouta, E | 1 |
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| Lyu, Y | 1 |
| Huang, J | 1 |
| Yu, N | 1 |
| Wen, Z | 1 |
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| Gupta, A | 1 |
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7 reviews available for chloroquine and Cardiac Failure
| Article | Year |
|---|---|
Review of Hydroxychloroquine Cardiotoxicity: Lessons From the COVID-19 Pandemic.
Topics: Cardiotoxicity; Chloroquine; COVID-19 Drug Treatment; Heart Failure; Humans; Hydroxychloroquine; Pan | 2022 |
COVID-19 and the burning issue of drug interaction: never forget the ECG.
Topics: Adenosine Monophosphate; Alanine; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Antiviral | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
SARS-CoV 2 Infection (Covid-19) and Cardiovascular Disease in Africa: Health Care and Socio-Economic Implications.
Topics: Acute Coronary Syndrome; Africa; Antimalarials; Arrhythmias, Cardiac; Cardiovascular Diseases; Chlor | 2021 |
Cardiomyopathy related to antimalarial therapy with illustrative case report.
Topics: Antimalarials; Chloroquine; Female; Heart Block; Heart Diseases; Heart Failure; Heart Transplantatio | 2007 |
Chloroquine cardiomyopathy with conduction disorders.
Topics: Antirheumatic Agents; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Chloroquine; Echocardiogra | 1999 |
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine | 1971 |
1 trial available for chloroquine and Cardiac Failure
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
10 other studies available for chloroquine and Cardiac Failure
| Article | Year |
|---|---|
No difference in biomarkers of ischemic heart injury and heart failure in patients with COVID-19 who received treatment with chloroquine phosphate and those who did not.
Topics: Aged; Antiviral Agents; Biomarkers; C-Reactive Protein; Case-Control Studies; Chloroquine; COVID-19; | 2021 |
Plasma-derived exosomes contribute to inflammation via the TLR9-NF-κB pathway in chronic heart failure patients.
Topics: Base Sequence; Cells, Cultured; Chloroquine; DNA, Mitochondrial; Exosomes; Gene Dosage; Heart Failur | 2017 |
Chloroquine-induced cardiomyopathy: a reversible cause of heart failure.
Topics: Antimalarials; Cardiomyopathies; Chloroquine; Echocardiography; Electrocardiography; Female; Heart F | 2018 |
Intermittent-hypoxia induced autophagy attenuates contractile dysfunction and myocardial injury in rat heart.
Topics: Adenine; Animals; Autophagy; Chloroquine; Heart Diseases; Heart Failure; Hypoxia; Lysosomes; Male; M | 2013 |
Cardiotoxicity after low-dose chloroquine antimalarial therapy.
Topics: Administration, Oral; Antimalarials; Biopsy; Chloroquine; Heart Failure; Heart Ventricles; Humans; M | 2009 |
[THE HEART AND POISONINGS].
Topics: Chloroquine; Diagnosis; Digitalis Glycosides; Heart; Heart Failure; Imipramine; Prognosis; Quinidine | 1964 |
LATENT INFECTIONS WITH PLASMODIUM OVALE MALARIA.
Topics: Africa, Western; Aminoquinolines; Canada; Chloroquine; Communicable Diseases; Diagnosis; Drug Therap | 1965 |
Heart transplantation in a patient with chloroquine-induced cardiomyopathy.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cardiomyopathy, Restrictive; Chloroquine; Female; Heart | 2004 |
Suicidal chloroquine poisoning: clinical course, autopsy findings, and chemical analysis.
Topics: Adolescent; Brain; Chloroquine; Disseminated Intravascular Coagulation; Fatal Outcome; Female; Foren | 1996 |
Generalised pustular drug rash.
Topics: Adult; Aged; Biguanides; Chloramphenicol; Chloroquine; Cross Reactions; Digoxin; Drug Eruptions; Fur | 1973 |