chloroquine has been researched along with Carcinoma, Renal Cell in 10 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Carcinoma, Renal Cell: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ursolic acid activates autophagy in renal carcinoma 786-O cells, probably by inhibiting hedgehog signaling pathway activity." | 1.72 | Inhibitory Effect of Ursolic Acid on Proliferation and Migration of Renal Carcinoma Cells and Its Mechanism. ( Lyu, X; Sun, L; Wang, D; Wang, J; Zhang, X, 2022) |
| "Renal cell carcinoma is an aggressive disease often asymptomatic and weakly chemo-radiosensitive." | 1.42 | Antagonistic effects of chloroquine on autophagy occurrence potentiate the anticancer effects of everolimus on renal cancer cells. ( Boccellino, M; Caraglia, M; Desiderio, V; Di Lorenzo, G; Grimaldi, A; Lombardi, A; Misso, G; Pantano, F; Santini, D; Vitiello, PP; Zappavigna, S; Zoccoli, A, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (90.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lyu, X | 1 |
| Zhang, X | 1 |
| Sun, L | 1 |
| Wang, J | 1 |
| Wang, D | 1 |
| Singla, M | 1 |
| Bhattacharyya, S | 1 |
| Makhov, P | 1 |
| Golovine, K | 1 |
| Teper, E | 1 |
| Kutikov, A | 1 |
| Mehrazin, R | 1 |
| Corcoran, A | 1 |
| Tulin, A | 1 |
| Uzzo, RG | 1 |
| Kolenko, VM | 1 |
| Grimaldi, A | 1 |
| Santini, D | 1 |
| Zappavigna, S | 1 |
| Lombardi, A | 1 |
| Misso, G | 1 |
| Boccellino, M | 1 |
| Desiderio, V | 1 |
| Vitiello, PP | 1 |
| Di Lorenzo, G | 1 |
| Zoccoli, A | 1 |
| Pantano, F | 1 |
| Caraglia, M | 1 |
| Kang, JH | 1 |
| Lee, JS | 1 |
| Hong, D | 1 |
| Lee, SH | 1 |
| Kim, N | 1 |
| Lee, WK | 1 |
| Sung, TW | 1 |
| Gong, YD | 1 |
| Kim, SY | 1 |
| Yin, P | 1 |
| Jia, J | 1 |
| Li, J | 1 |
| Song, Y | 1 |
| Zhang, Y | 1 |
| Chen, F | 1 |
| Zhou, L | 1 |
| Yang, H | 1 |
| Bray, K | 1 |
| Mathew, R | 1 |
| Lau, A | 1 |
| Kamphorst, JJ | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Chen, HY | 1 |
| Ghavami, A | 1 |
| Stein, M | 1 |
| DiPaola, RS | 1 |
| Zhang, D | 1 |
| Rabinowitz, JD | 1 |
| White, E | 1 |
| Zhan, YH | 1 |
| Liu, J | 1 |
| Qu, XJ | 1 |
| Hou, KZ | 1 |
| Wang, KF | 1 |
| Liu, YP | 1 |
| Wu, B | 1 |
| Li, H | 1 |
| Jin, X | 1 |
| Zhang, Z | 1 |
| Xing, Y | 1 |
| Kong, X | 1 |
10 other studies available for chloroquine and Carcinoma, Renal Cell
| Article | Year |
|---|---|
Inhibitory Effect of Ursolic Acid on Proliferation and Migration of Renal Carcinoma Cells and Its Mechanism.
Topics: Apoptosis; Autophagy; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Chloroquine; Hedg | 2022 |
Autophagy as a potential therapeutic target during epithelial to mesenchymal transition in renal cell carcinoma: An in vitro study.
Topics: Autophagy; Carcinoma, Renal Cell; Cell Culture Techniques; Cell Line, Tumor; Chloroquine; Epithelial | 2017 |
Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death.
Topics: Animals; Apoptosis; Autophagy; Breast Neoplasms; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proli | 2014 |
Antagonistic effects of chloroquine on autophagy occurrence potentiate the anticancer effects of everolimus on renal cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Carcinoma, Ren | 2015 |
Renal cell carcinoma escapes death by p53 depletion through transglutaminase 2-chaperoned autophagy.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Autophagy; Carcinoma, Renal Cell; Cell Line, Tumor; | 2016 |
ABT-737, a Bcl-2 Selective Inhibitor, and Chloroquine Synergistically Kill Renal Cancer Cells.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosi | 2016 |
The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.
Topics: Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Carcinoma, Renal Cell; Cell Line, T | 2011 |
Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition.
Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Antioxidants; Autophagy; Basal Metab | 2012 |
β-Elemene induces apoptosis in human renal-cell carcinoma 786-0 cells through inhibition of MAPK/ERK and PI3K/Akt/ mTOR signalling pathways.
Topics: Adenine; Apoptosis; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Chloroquine; Extracellul | 2012 |
Inhibition of autophagy enhances apoptosis induced by the PI3K/AKT/mTor inhibitor NVP-BEZ235 in renal cell carcinoma cells.
Topics: Adenine; Apoptosis; Autophagy; Carcinoma, Renal Cell; Cell Line, Tumor; Chloroquine; Drug Synergism; | 2013 |