chloroquine has been researched along with Cancer of the Thyroid in 5 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A rat medullary thyroid carcinoma cell line, CA-77, was shown to express the cholecystokinin (CCK) gene." | 7.68 | Expression and processing of procholecystokinin in a rat medullary thyroid carcinoma cell line. ( Odum, L; Rehfeld, JF, 1990) |
| "The present study investigated the effect of valproic acid (VPA) on the inhibition of RET signaling and induction of apoptosis in human thyroid carcinoma cells." | 3.81 | Induction of apoptosis and autophagy in metastatic thyroid cancer cells by valproic acid (VPA). ( Dong, JD; Xu, D; Xu, Y; Ye, B; Zhang, Y; Zhang, YL; Zhu, SJ, 2015) |
| "A rat medullary thyroid carcinoma cell line, CA-77, was shown to express the cholecystokinin (CCK) gene." | 3.68 | Expression and processing of procholecystokinin in a rat medullary thyroid carcinoma cell line. ( Odum, L; Rehfeld, JF, 1990) |
| "Chloroquine (CQ) is an autophagy inhibitor that has been reported to increase sensitivity to various cancer treatments." | 1.48 | Inhibition of autophagy enhances the targeted therapeutic effect of sorafenib in thyroid cancer. ( Ge, M; Jin, S; Li, L; Long, B; Yang, M; Ye, T; Ye, X; Yi, H; Zhang, L, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holm, TM | 1 |
| Bian, ZC | 1 |
| Manupati, K | 1 |
| Guan, JL | 1 |
| Yi, H | 1 |
| Ye, T | 1 |
| Ge, M | 1 |
| Yang, M | 1 |
| Zhang, L | 1 |
| Jin, S | 1 |
| Ye, X | 1 |
| Long, B | 1 |
| Li, L | 1 |
| Xu, Y | 1 |
| Xu, D | 1 |
| Zhu, SJ | 1 |
| Ye, B | 1 |
| Dong, JD | 1 |
| Zhang, YL | 1 |
| Zhang, Y | 1 |
| NELSON, AA | 1 |
| FITZHUGH, OG | 1 |
| Odum, L | 1 |
| Rehfeld, JF | 1 |
5 other studies available for chloroquine and Cancer of the Thyroid
| Article | Year |
|---|---|
Inhibition of autophagy mitigates cell migration and invasion in thyroid cancer.
Topics: Autophagy; Cell Line, Tumor; Cell Movement; Chloroquine; Humans; Macrolides; Neoplasm Invasiveness; | 2022 |
Inhibition of autophagy enhances the targeted therapeutic effect of sorafenib in thyroid cancer.
Topics: Animals; Antineoplastic Agents; Autophagy; Autophagy-Related Protein 5; Cell Line, Tumor; Chloroquin | 2018 |
Induction of apoptosis and autophagy in metastatic thyroid cancer cells by valproic acid (VPA).
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma; Cell Line, Tumor; Cell Proliferation; Chloro | 2015 |
Chloroquine (SN-7618) pathologic changes observed in rats which for 2 years had been fed various proportions.
Topics: Animals; Chloroquine; Neoplasms; Rats; Thyroid Gland; Thyroid Neoplasms | 1948 |
Expression and processing of procholecystokinin in a rat medullary thyroid carcinoma cell line.
Topics: Animals; Carcinoma; Chloroquine; Cholecystokinin; Chromatography, Gel; Colchicine; Dexamethasone; Ge | 1990 |