chloroquine has been researched along with Cafe-au-Lait Spots with Pulmonic Stenosis in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neurofibromatosis type 1 is an autosomal dominant genetic disorder caused by mutation in the neurofibromin 1 (NF1) gene." | 5.62 | Metalloproteinase 1 downregulation in neurofibromatosis 1: Therapeutic potential of antimalarial hydroxychloroquine and chloroquine. ( Furue, M; Kato, T; Takai-Yumine, A; Tsuji, G, 2021) |
| " Moreover, similar to wild-type littermates, Nf1± mice developed inflammation-induced heat and mechanical hypersensitivity, capsaicin-induced nocifensive behavior, histamine-dependent or -independent scratching, and chronic constriction injury-induced cold allodynia." | 3.79 | Assessment of pain and itch behavior in a mouse model of neurofibromatosis type 1. ( Brenner, DS; Gereau, RW; Gutmann, DH; O'Brien, DE, 2013) |
| "Neurofibromatosis type 1 is an autosomal dominant genetic disorder caused by mutation in the neurofibromin 1 (NF1) gene." | 1.62 | Metalloproteinase 1 downregulation in neurofibromatosis 1: Therapeutic potential of antimalarial hydroxychloroquine and chloroquine. ( Furue, M; Kato, T; Takai-Yumine, A; Tsuji, G, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsuji, G | 1 |
| Takai-Yumine, A | 1 |
| Kato, T | 1 |
| Furue, M | 1 |
| O'Brien, DE | 1 |
| Brenner, DS | 1 |
| Gutmann, DH | 1 |
| Gereau, RW | 1 |
2 other studies available for chloroquine and Cafe-au-Lait Spots with Pulmonic Stenosis
| Article | Year |
|---|---|
Metalloproteinase 1 downregulation in neurofibromatosis 1: Therapeutic potential of antimalarial hydroxychloroquine and chloroquine.
Topics: Antimalarials; Cells, Cultured; Chloroquine; Down-Regulation; Fibroblasts; Humans; Hydroxychloroquin | 2021 |
Assessment of pain and itch behavior in a mouse model of neurofibromatosis type 1.
Topics: Animals; Capsaicin; Chloroquine; Constriction; Disease Models, Animal; Functional Laterality; Histam | 2013 |