chloroquine has been researched along with Break-Bone Fever in 9 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dengue is the most important arboviral disease in the world." | 6.78 | Chloroquine use improves dengue-related symptoms. ( Borges, MC; Castro, LA; Fonseca, BA, 2013) |
| "Dengue is the most important arboviral disease in the world." | 2.78 | Chloroquine use improves dengue-related symptoms. ( Borges, MC; Castro, LA; Fonseca, BA, 2013) |
| "Dengue is a major public health problem in tropical and subtropical countries." | 2.76 | Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue. ( Farrar, J; Minh, NN; Simmons, CP; Tran, HT; Tricou, V, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Behnam, MA | 1 |
| Nitsche, C | 1 |
| Boldescu, V | 1 |
| Klein, CD | 1 |
| Murugan, K | 1 |
| Panneerselvam, C | 1 |
| Subramaniam, J | 1 |
| Paulpandi, M | 1 |
| Rajaganesh, R | 1 |
| Vasanthakumaran, M | 1 |
| Madhavan, J | 1 |
| Shafi, SS | 1 |
| Roni, M | 1 |
| Portilla-Pulido, JS | 1 |
| Mendez, SC | 1 |
| Duque, JE | 1 |
| Wang, L | 1 |
| Aziz, AT | 1 |
| Chandramohan, B | 1 |
| Dinesh, D | 1 |
| Piramanayagam, S | 1 |
| Hwang, JS | 1 |
| Thangaraju, P | 1 |
| Narasimhan, G | 1 |
| Ramamurthy, VA | 1 |
| Gurunthalingam, MP | 1 |
| Yella, SST | 1 |
| Venkatesan, S | 1 |
| Thangaraju, E | 1 |
| Borges, MC | 1 |
| Castro, LA | 1 |
| Fonseca, BA | 1 |
| Farias, KJ | 1 |
| Machado, PR | 1 |
| Muniz, JA | 1 |
| Imbeloni, AA | 1 |
| da Fonseca, BA | 1 |
| Bekerman, E | 1 |
| Einav, S | 1 |
| Tricou, V | 2 |
| Minh, NN | 2 |
| Van, TP | 1 |
| Lee, SJ | 1 |
| Farrar, J | 2 |
| Wills, B | 1 |
| Tran, HT | 2 |
| Simmons, CP | 2 |
| Permal, S | 1 |
| Rambeloarisoa, J | 1 |
| Dhôte, R | 1 |
| Christoforov, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Study to Evaluate the Safety and Antiviral Efficacy of Hydroxychloroquine in Patients With Newly Diagnosed COVID-19 Compared to Standard of Care Treatment[NCT04334967] | Phase 4 | 13 participants (Actual) | Interventional | 2020-03-30 | Suspended (stopped due to suspected unfavorable risk/benefit assessment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chloroquine and Break-Bone Fever
| Article | Year |
|---|---|
The Medicinal Chemistry of Dengue Virus.
Topics: Antiviral Agents; Chemistry, Pharmaceutical; Dengue; Dengue Virus; Humans; Molecular Conformation; S | 2016 |
3 trials available for chloroquine and Break-Bone Fever
| Article | Year |
|---|---|
Chloroquine use improves dengue-related symptoms.
Topics: Adult; Antiviral Agents; Chloroquine; Dengue; Double-Blind Method; Female; Humans; Male; Pain Manage | 2013 |
A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults.
Topics: Adolescent; Adult; Antigens, Viral; Antiviral Agents; Chloroquine; Dengue; Double-Blind Method; Fema | 2010 |
Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue.
Topics: Adolescent; Adult; Antigens, Viral; Antiviral Agents; Chloroquine; Dengue; Dengue Virus; Female; Hum | 2011 |
5 other studies available for chloroquine and Break-Bone Fever
| Article | Year |
|---|---|
Synthesis of new series of quinoline derivatives with insecticidal effects on larval vectors of malaria and dengue diseases.
Topics: Animals; Antimalarials; Chloroquine; Dengue; Insecticides; Larva; Malaria; Metal Nanoparticles; Mice | 2022 |
Molecular Docking Analysis of
Topics: Chloroquine; Dengue; Humans; Justicia; Molecular Docking Simulation; Plant Preparations; Receptors, | 2023 |
Antiviral activity of chloroquine against dengue virus type 2 replication in Aotus monkeys.
Topics: Animals; Antiviral Agents; Aotidae; Chloroquine; Cytokines; Dengue; Dengue Virus; Disease Models, An | 2015 |
Infectious disease. Combating emerging viral threats.
Topics: Adenine; Adenosine; Antiviral Agents; Benzamides; Chloroquine; Communicable Diseases, Emerging; Cycl | 2015 |
[A story of the absurd!].
Topics: Aged; Antimalarials; Chloroquine; Dengue; Diagnosis, Differential; Female; Humans; Malaria, Falcipar | 1999 |