chloroquine has been researched along with Brain Swelling in 6 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malaria is an infectious disease of major worldwide clinical importance that causes a variety of severe, or complicated, syndromes including cerebral malaria, which is often fatal." | 1.51 | Integrin αDβ2 influences cerebral edema, leukocyte accumulation and neurologic outcomes in experimental severe malaria. ( Azevedo-Quintanilha, IG; Bozza, PT; Campbell, RA; Castro-Faria-Neto, HC; Estato, V; Ferreira, AC; Nascimento, DO; Reis, PA; Silva, TI; Vieira-de-Abreu, A; Weyrich, AS; Zimmerman, GA, 2019) |
| "In a man who had been in a coma for 24 hours with cerebral malaria dexamethasone had a dramatic, and probably life-saving, effect." | 1.25 | Use of dexamethasone in cerebral malaria. ( Dickinson, CJ; Woodruff, AW, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Azevedo-Quintanilha, IG | 1 |
| Vieira-de-Abreu, A | 1 |
| Ferreira, AC | 1 |
| Reis, PA | 1 |
| Silva, TI | 1 |
| Nascimento, DO | 1 |
| Campbell, RA | 1 |
| Estato, V | 1 |
| Weyrich, AS | 1 |
| Bozza, PT | 1 |
| Zimmerman, GA | 1 |
| Castro-Faria-Neto, HC | 1 |
| Liu, YY | 1 |
| Zhang, TY | 1 |
| Xue, X | 1 |
| Liu, DM | 1 |
| Zhang, HT | 1 |
| Yuan, LL | 1 |
| Liu, YL | 1 |
| Yang, HL | 1 |
| Sun, SB | 1 |
| Zhang, C | 1 |
| Xu, HS | 1 |
| Wu, CF | 1 |
| Yang, JY | 1 |
| Cui, CM | 1 |
| Gao, JL | 1 |
| Cui, Y | 1 |
| Sun, LQ | 1 |
| Wang, YC | 1 |
| Wang, KJ | 1 |
| Li, R | 1 |
| Tian, YX | 1 |
| Cui, JZ | 1 |
| Holmin, S | 1 |
| Mathiesen, T | 1 |
| Havens, PL | 1 |
| Splaingard, ML | 1 |
| Bousounis, D | 1 |
| Hoffman, GM | 1 |
| Woodruff, AW | 1 |
| Dickinson, CJ | 1 |
6 other studies available for chloroquine and Brain Swelling
| Article | Year |
|---|---|
Integrin αDβ2 influences cerebral edema, leukocyte accumulation and neurologic outcomes in experimental severe malaria.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; CD11 Antigens; Chloroquine; Disease Models, Animal | 2019 |
Pseudoginsenoside-F11 attenuates cerebral ischemic injury by alleviating autophagic/lysosomal defects.
Topics: Animals; Apoptosis; Autophagy; Brain; Brain Edema; Brain Ischemia; Chloroquine; Disease Models, Anim | 2017 |
Chloroquine exerts neuroprotection following traumatic brain injury via suppression of inflammation and neuronal autophagic death.
Topics: Animals; Antigens, Nuclear; Autophagy; Biomarkers; Brain Edema; Brain Injuries; Chloroquine; Disease | 2015 |
Dexamethasone and colchicine reduce inflammation and delayed oedema following experimental brain contusion.
Topics: Animals; Anti-Inflammatory Agents; Brain; Brain Concussion; Brain Damage, Chronic; Brain Edema; Chlo | 1996 |
Survival after chloroquine ingestion in a child.
Topics: Brain Edema; Chloroquine; Coma; Electroencephalography; Evoked Potentials; Humans; Infant; Male; Ner | 1988 |
Use of dexamethasone in cerebral malaria.
Topics: Adult; Brain Edema; Chloroquine; Coma; Dexamethasone; Humans; Malaria; Male | 1968 |