chloroquine has been researched along with Brain Abscess in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Brain Abscess: A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 3-year-old boy with hepatopulmonary amebiasis treated with chloroquine phosphate for 20 days subsequently was found to have three brain abscesses and responded to prolonged combined therapy with metronidazole and chloroquine phosphate." | 3.65 | Multiple cerebral abscesses complicating hepatopulmonary amebiasis. ( Faehnle, ST; Hughes, FB; Simon, JL, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Powell, SJ | 1 |
| Wilmot, AJ | 1 |
| Macleod, IN | 1 |
| Elsdon-Dew, R | 1 |
| Hughes, FB | 1 |
| Faehnle, ST | 1 |
| Simon, JL | 1 |
1 trial available for chloroquine and Brain Abscess
| Article | Year |
|---|---|
A comparative trial of dehydroemetine and emetine hydrochloride in identical dosage in amoebic liver abscess.
Topics: Adult; Amebicides; Brain Abscess; Chloroquine; Drug Synergism; Electrocardiography; Emetine; Heart; | 1967 |
1 other study available for chloroquine and Brain Abscess
| Article | Year |
|---|---|
Multiple cerebral abscesses complicating hepatopulmonary amebiasis.
Topics: Brain Abscess; Child, Preschool; Chloroquine; Drug Therapy, Combination; Entamoeba histolytica; Huma | 1975 |