chloroquine has been researched along with Bloom Syndrome in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Bloom Syndrome: An autosomal recessive disorder characterized by telangiectatic ERYTHEMA of the face, photosensitivity, DWARFISM and other abnormalities, and a predisposition toward developing cancer. The Bloom syndrome gene (BLM) encodes a RecQ-like DNA helicase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The gene responsible for Werner syndrome codes for a RecQ-type DNA helicase and is believed to be involved in different aspects of DNA repair, replication, and transcription." | 1.34 | Werner syndrome protein prevents DNA breaks upon chromatin structure alteration. ( Chavez, A; Johnson, FB; Lebel, M; Massip, L; Turaga, RV, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Turaga, RV | 1 |
| Massip, L | 1 |
| Chavez, A | 1 |
| Johnson, FB | 1 |
| Lebel, M | 1 |
1 other study available for chloroquine and Bloom Syndrome
| Article | Year |
|---|---|
Werner syndrome protein prevents DNA breaks upon chromatin structure alteration.
Topics: Animals; Bloom Syndrome; Cell Line; Cell Line, Tumor; Cellular Senescence; Chloroquine; Chromatin; D | 2007 |