chloroquine has been researched along with Blastomyces brasiliensis Infection in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thus, CHLOR was effective in the treatment of murine paracoccidioidomycosis, suggesting the potential use of this drug in patients' treatment." | 1.33 | Chloroquine inhibits Paracoccidioides brasiliensis survival within human monocytes by limiting the availability of intracellular iron. ( Calvi, SA; Dias-Melicio, LA; Moreira, AP; Soares, AM, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dias-Melicio, LA | 2 |
| Moreira, AP | 1 |
| Calvi, SA | 2 |
| Soares, AM | 2 |
| Bordon, AP | 1 |
| Golim, MA | 1 |
| Peraçoli, MT | 1 |
2 other studies available for chloroquine and Blastomyces brasiliensis Infection
| Article | Year |
|---|---|
Chloroquine inhibits Paracoccidioides brasiliensis survival within human monocytes by limiting the availability of intracellular iron.
Topics: Animals; Chloroquine; Drug Interactions; Female; Ferric Compounds; Humans; Iron; Lung; Male; Mice; M | 2006 |
Chloroquine is therapeutic in murine experimental model of paracoccidioidomycosis.
Topics: Animals; Chloroquine; Disease Models, Animal; Hydrogen Peroxide; Interleukin-6; Iron; Macrophages, P | 2007 |