chloroquine has been researched along with B16 Melanoma in 9 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with chloroquine at a dose of 62 mg/kg i." | 5.29 | Antimelanoma activity of chloroquine, an antimalarial agent with high affinity for melanin. ( Fujita, K; Hasegawa, K; Inoue, S; Ito, S; Wakamatsu, K, 1993) |
| "Chloroquine (CQ) has been evaluated as an autophagy blocker for cancer treatment, but it is unknown if it acts solely by inhibiting cancer cell autophagy." | 1.40 | Tumor vessel normalization by chloroquine independent of autophagy. ( Agostinis, P; Annaert, W; Boulanger, C; Carmeliet, P; De Bock, K; Dejana, E; Dewerchin, M; Garmyn, M; Georgiadou, M; Gerhardt, H; Ghesquière, B; Kuchnio, A; Maes, H; Moens, S; Nys, K; Peric, A; Quaegebeur, A; Radtke, F; Schoors, S; Vankelecom, H; Vinckier, S; Vion, AC; Wouters, J, 2014) |
| "Treatment with chloroquine at a dose of 62 mg/kg i." | 1.29 | Antimelanoma activity of chloroquine, an antimalarial agent with high affinity for melanin. ( Fujita, K; Hasegawa, K; Inoue, S; Ito, S; Wakamatsu, K, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Gil, D | 1 |
| Laidler, P | 1 |
| Zarzycka, M | 1 |
| Dulińska-Litewka, J | 1 |
| Buri, MV | 1 |
| Domingues, TM | 1 |
| Paredes-Gamero, EJ | 1 |
| Casaes-Rodrigues, RL | 1 |
| Rodrigues, EG | 1 |
| Miranda, A | 1 |
| Maes, H | 1 |
| Kuchnio, A | 1 |
| Peric, A | 1 |
| Moens, S | 1 |
| Nys, K | 1 |
| De Bock, K | 1 |
| Quaegebeur, A | 1 |
| Schoors, S | 1 |
| Georgiadou, M | 1 |
| Wouters, J | 1 |
| Vinckier, S | 1 |
| Vankelecom, H | 1 |
| Garmyn, M | 1 |
| Vion, AC | 1 |
| Radtke, F | 1 |
| Boulanger, C | 1 |
| Gerhardt, H | 1 |
| Dejana, E | 1 |
| Dewerchin, M | 1 |
| Ghesquière, B | 1 |
| Annaert, W | 1 |
| Agostinis, P | 1 |
| Carmeliet, P | 1 |
| Junco, JJ | 1 |
| Mancha-Ramirez, A | 1 |
| Malik, G | 1 |
| Wei, SJ | 1 |
| Kim, DJ | 1 |
| Liang, H | 1 |
| Slaga, TJ | 1 |
| Zhang, X | 1 |
| Xu, Q | 1 |
| Zhang, Z | 1 |
| Cheng, W | 1 |
| Cao, W | 1 |
| Jiang, C | 1 |
| Han, C | 1 |
| Li, J | 1 |
| Hua, Z | 1 |
| Negroiu, G | 1 |
| Dwek, RA | 1 |
| Petrescu, SM | 1 |
| Inoue, S | 1 |
| Hasegawa, K | 1 |
| Ito, S | 1 |
| Wakamatsu, K | 1 |
| Fujita, K | 1 |
| Djordevic, B | 1 |
| Lange, CS | 1 |
| Rotman, M | 1 |
| Oikawa, A | 1 |
| Saeki, H | 1 |
| Akiyama, T | 1 |
| Matsumoto, J | 1 |
9 other studies available for chloroquine and B16 Melanoma
| Article | Year |
|---|---|
Inhibition Effect of Chloroquine and Integrin-Linked Kinase Knockdown on Translation in Melanoma Cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Autophagy-Related Protein-1 Homo | 2021 |
Resistance to degradation and cellular distribution are important features for the antitumor activity of gomesin.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antimicrobial Cationic Peptides; Antineoplast | 2013 |
Tumor vessel normalization by chloroquine independent of autophagy.
Topics: Angiogenesis Inhibitors; Animals; Autophagy; Autophagy-Related Protein 5; Camptothecin; Cell Line, T | 2014 |
Ursolic acid and resveratrol synergize with chloroquine to reduce melanoma cell viability.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; Cell Survival; | 2015 |
Chloroquine enhanced the anticancer capacity of VNP20009 by inhibiting autophagy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Bacterial Vaccines; Cell Line, T | 2016 |
Tyrosinase-related protein-2 and -1 are trafficked on distinct routes in B16 melanoma cells.
Topics: Animals; Cell Line, Tumor; Chloroquine; Endoplasmic Reticulum; Golgi Apparatus; Intramolecular Oxido | 2005 |
Antimelanoma activity of chloroquine, an antimalarial agent with high affinity for melanin.
Topics: Animals; Antimalarials; Antineoplastic Agents; Chloroquine; Chromatography, High Pressure Liquid; Do | 1993 |
Potentiation of radiation lethality in mouse melanoma cells by mild hyperthermia and chloroquine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Survival; Chloroquine; Dose-Response Relationship, Drug; | 1992 |
Electron microscopic evidence for stimulation of melanosomal maturation by lysosomotropic agents and monensin in cultured B16 mouse melanoma cells.
Topics: Ammonium Chloride; Animals; Cell Division; Cell Line; Chloroquine; Cytoplasmic Granules; Lysosomes; | 1987 |