chloroquine has been researched along with Autoimmune Diabetes in 8 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 16-year old girl with insulin-dependent diabetes mellitus (8 years' duration) developed tropic malaria 7 weeks after her return from Kenya despite a longtime prophylaxis using pyrimethamine and sulfadoxine (Fansidar)." | 7.67 | [Chloroquine and pyrimethamine/sulfadoxine resistant malaria tropica in a child with diabetes mellitus]. ( Bienzle, U; Burger, W; Kroll, MH; Weber, B, 1984) |
| "A 16-year old girl with insulin-dependent diabetes mellitus (8 years' duration) developed tropic malaria 7 weeks after her return from Kenya despite a longtime prophylaxis using pyrimethamine and sulfadoxine (Fansidar)." | 3.67 | [Chloroquine and pyrimethamine/sulfadoxine resistant malaria tropica in a child with diabetes mellitus]. ( Bienzle, U; Burger, W; Kroll, MH; Weber, B, 1984) |
| "Chloroquine treatment delayed the spontaneous onset of diabetes in NOD mice, coincident with the decreased activation of PLN DCs." | 1.36 | TLR9 blockade inhibits activation of diabetogenic CD8+ T cells and delays autoimmune diabetes. ( Dutz, JP; Finegood, D; Geng, X; Lee, AS; Santamaria, P; Shameli, A; Zhang, Y, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, X | 1 |
| Zhao, X | 1 |
| Cheng, R | 1 |
| Huang, Y | 1 |
| de Almeida Júnior, RF | 1 |
| de Souza, KSC | 1 |
| Galdino, OA | 1 |
| da Silva Junior, AA | 1 |
| Arrais, RF | 1 |
| Machado, PRL | 1 |
| Farias, KJS | 1 |
| de Rezende, AA | 1 |
| Kang, JM | 1 |
| Lee, HS | 1 |
| Kim, J | 2 |
| Yang, DH | 1 |
| Jeong, HY | 1 |
| Lee, YH | 1 |
| Kim, DJ | 1 |
| Park, SH | 1 |
| Sung, M | 1 |
| An, HJ | 1 |
| Lee, SH | 1 |
| Lee, SY | 1 |
| Liu, M | 1 |
| Peng, J | 1 |
| Tai, N | 1 |
| Pearson, JA | 1 |
| Hu, C | 1 |
| Guo, J | 1 |
| Hou, L | 1 |
| Zhao, H | 1 |
| Wong, FS | 1 |
| Wen, L | 1 |
| Zhang, Y | 1 |
| Lee, AS | 1 |
| Shameli, A | 1 |
| Geng, X | 1 |
| Finegood, D | 1 |
| Santamaria, P | 1 |
| Dutz, JP | 1 |
| Zipris, D | 1 |
| Lien, E | 1 |
| Nair, A | 1 |
| Xie, JX | 1 |
| Greiner, DL | 1 |
| Mordes, JP | 1 |
| Rossini, AA | 1 |
| Blazar, BR | 1 |
| Whitley, CB | 1 |
| Kitabchi, AE | 1 |
| Tsai, MY | 1 |
| Santiago, J | 1 |
| White, N | 1 |
| Stentz, FB | 1 |
| Brown, DM | 1 |
| Kroll, MH | 1 |
| Bienzle, U | 1 |
| Burger, W | 1 |
| Weber, B | 1 |
8 other studies available for chloroquine and Autoimmune Diabetes
| Article | Year |
|---|---|
Autophagy attenuates high glucose-induced oxidative injury to lens epithelial cells.
Topics: Animals; Autophagy; Cataract; Cells, Cultured; Chloroquine; Culture Media; Diabetes Mellitus, Experi | 2020 |
Chloroquine as a promising adjuvant therapy for type 1 Diabetes Mellitus.
Topics: Adolescent; Anti-Inflammatory Agents; Case-Control Studies; Cell Proliferation; Cell Survival; Chemo | 2020 |
Beneficial Effect of Chloroquine and Amodiaquine on Type 1 Diabetic Tubulopathy by Attenuating Mitochondrial Nox4 and Endoplasmic Reticulum Stress.
Topics: Amodiaquine; Animals; Apoptosis; Cells, Cultured; Chloroquine; Diabetes Mellitus, Experimental; Diab | 2020 |
Toll-like receptor 9 negatively regulates pancreatic islet beta cell growth and function in a mouse model of type 1 diabetes.
Topics: Animals; Chloroquine; Diabetes Mellitus, Type 1; Female; Flow Cytometry; Glucose Tolerance Test; Ins | 2018 |
TLR9 blockade inhibits activation of diabetogenic CD8+ T cells and delays autoimmune diabetes.
Topics: Animals; CD8-Positive T-Lymphocytes; Cell Differentiation; Chloroquine; Clone Cells; CpG Islands; Di | 2010 |
TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat.
Topics: Animals; B-Lymphocytes; Breeding; Cells, Cultured; Chloroquine; Diabetes Mellitus, Type 1; Disease S | 2007 |
In vivo chloroquine-induced inhibition of insulin degradation in a diabetic patient with severe insulin resistance.
Topics: Adipose Tissue; Adult; alpha-Galactosidase; beta-N-Acetylhexosaminidases; Biopsy; Chloroquine; Diabe | 1984 |
[Chloroquine and pyrimethamine/sulfadoxine resistant malaria tropica in a child with diabetes mellitus].
Topics: Adolescent; Chloroquine; Diabetes Mellitus, Type 1; Diagnosis, Differential; Doxycycline; Drug Resis | 1984 |