chloroquine has been researched along with Atheroma in 4 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These findings suggest that chloroquine ameliorates atherosclerosis and stabilizes plaque by modulating Tregs differentiation through the regulation of the ATM/AMPK/mTOR pathway." | 8.31 | Chloroquine Alleviates Atherosclerosis by Modulating Regulatory T Cells Through the ATM/AMPK/mTOR Signaling Pathway in ApoE -/- Mice. ( Gao, J; Huang, Q; Li, S; Liu, D; Meng, W; Mo, X; Tian, H; Zhang, Y, 2023) |
| "These findings suggest that chloroquine ameliorates atherosclerosis and stabilizes plaque by modulating Tregs differentiation through the regulation of the ATM/AMPK/mTOR pathway." | 4.31 | Chloroquine Alleviates Atherosclerosis by Modulating Regulatory T Cells Through the ATM/AMPK/mTOR Signaling Pathway in ApoE -/- Mice. ( Gao, J; Huang, Q; Li, S; Liu, D; Meng, W; Mo, X; Tian, H; Zhang, Y, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Z | 1 |
| Ouyang, C | 1 |
| Zhang, H | 1 |
| Gu, Y | 1 |
| Deng, Y | 1 |
| Du, C | 1 |
| Cui, C | 1 |
| Li, S | 2 |
| Wang, W | 1 |
| Kong, W | 1 |
| Chen, J | 1 |
| Cai, J | 1 |
| Geng, B | 1 |
| Liu, D | 1 |
| Zhang, Y | 2 |
| Huang, Q | 1 |
| Meng, W | 1 |
| Gao, J | 1 |
| Mo, X | 1 |
| Tian, H | 1 |
| Liang, X | 1 |
| Hou, X | 1 |
| Yang, Y | 1 |
| Liu, H | 1 |
| Guo, R | 1 |
| Yang, Z | 1 |
| Yang, L | 1 |
| Emanuel, R | 1 |
| Sergin, I | 1 |
| Bhattacharya, S | 1 |
| Turner, J | 1 |
| Epelman, S | 1 |
| Settembre, C | 1 |
| Diwan, A | 1 |
| Ballabio, A | 1 |
| Razani, B | 1 |
4 other studies available for chloroquine and Atheroma
| Article | Year |
|---|---|
Vascular smooth muscle cell-derived hydrogen sulfide promotes atherosclerotic plaque stability via TFEB (transcription factor EB)-mediated autophagy.
Topics: Atherosclerosis; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Biomarkers; | 2022 |
Chloroquine Alleviates Atherosclerosis by Modulating Regulatory T Cells Through the ATM/AMPK/mTOR Signaling Pathway in ApoE -/- Mice.
Topics: AMP-Activated Protein Kinases; Animals; Apolipoproteins E; Ataxia Telangiectasia; Atherosclerosis; C | 2023 |
The feedback loop of "EMMPRIN/NF-κB" worsens atherosclerotic plaque via suppressing autophagy in macrophage.
Topics: Animals; Apolipoproteins E; Apoptosis; Autophagy; Basigin; Chloroquine; Cytokines; Down-Regulation; | 2018 |
Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Autophagy; Autophagy-Related Protein 5; Basic Helix-Loo | 2014 |