chloroquine has been researched along with Astrocytoma in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with Dabrafenib and Trametinib was started, and tumor size increased in size after 14 months of treatment." | 1.56 | Using personalized medicine in gliomas: a genomic approach to diagnosis and overcoming treatment resistance in a case with pleomorphic xanthoastrocytoma. ( Evernden, BR; Forsyth, P; Fusco, MJ; Macaulay, RJ; Peguero, E; Piña, Y; Smalley, KS; Walko, CM, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piña, Y | 1 |
| Fusco, MJ | 1 |
| Macaulay, RJ | 1 |
| Walko, CM | 1 |
| Peguero, E | 1 |
| Evernden, BR | 1 |
| Smalley, KS | 1 |
| Forsyth, P | 1 |
| Chu, BC | 1 |
| Howell, SB | 1 |
2 other studies available for chloroquine and Astrocytoma
| Article | Year |
|---|---|
Using personalized medicine in gliomas: a genomic approach to diagnosis and overcoming treatment resistance in a case with pleomorphic xanthoastrocytoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Chloroquine; Drug Resi | 2020 |
Differential toxicity of carrier-bound methotrexate toward human lymphocytes, marrow and tumor cells.
Topics: Astrocytoma; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Chloroquine; Deoxyuridine; Humans; In | 1981 |