chloroquine has been researched along with Asthma in 38 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The object of this review was to assess the efficacy of adding chloroquine to oral corticosteroids in patients with chronic asthma who are dependent on oral corticosteroids with the intention of minimising or eventually eliminating the use of these oral steroids." | 8.82 | Chloroquine as a steroid sparing agent for asthma. ( Bara, A; Dean, T; Dewey, A; Lasserson, TJ; Walters, EH, 2003) |
| "To investigate the effect of chloroquine on airway hyperresponsiveness in asthmatic mice and explore the possible mechanism." | 7.81 | [Inhibitory effect of chloroquine on airway hyperresponsiveness in asthmatic mice]. ( Fu, Z; Hu, XY; Liu, EM; Sun, XC; Wang, LJ, 2015) |
| "The object of this review was to assess the efficacy of adding chloroquine to oral corticosteroids in patients with chronic asthma who are dependent on oral corticosteroids with the intention of minimising or eventually eliminating the use of these oral steroids." | 4.82 | Chloroquine as a steroid sparing agent for asthma. ( Bara, A; Dean, T; Dewey, A; Lasserson, TJ; Walters, EH, 2003) |
| "To investigate the effect of chloroquine on airway hyperresponsiveness in asthmatic mice and explore the possible mechanism." | 3.81 | [Inhibitory effect of chloroquine on airway hyperresponsiveness in asthmatic mice]. ( Fu, Z; Hu, XY; Liu, EM; Sun, XC; Wang, LJ, 2015) |
| "Current asthma therapies fail to target airway remodeling that correlates with asthma severity driving disease progression that ultimately leads to loss of lung function." | 1.51 | Autophagy Activation in Asthma Airways Remodeling. ( Deshpande, DA; Ghavami, S; Haghi, M; McAlinden, KD; Oliver, BG; Sharma, P; Sohal, SS; Xenaki, D, 2019) |
| "TAS2R agonists attenuated features of airway remodeling including smooth muscle mass, extracellular matrix deposition and pro-fibrotic signaling, and also prevented mucus accumulation and development of AHR in mice." | 1.46 | Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice. ( Deshpande, DA; Knight, MJ; Nayak, AP; Oliver, B; Pan, S; Sharma, P; Tang, F; Wang, N; Yi, R, 2017) |
| "Sixty-seven patients with bronchial asthma treated with the bronchodilator insanovin for 4 weeks were followed up." | 1.32 | [Insanovin aerosol therapy in the treatment of bronchial asthma]. ( Insanov, AB; Mustafaeva, LI, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (76.32) | 18.7374 |
| 1990's | 1 (2.63) | 18.2507 |
| 2000's | 2 (5.26) | 29.6817 |
| 2010's | 4 (10.53) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Zhao, Y | 1 |
| Zhang, X | 1 |
| Tu, W | 1 |
| Wan, R | 1 |
| Shen, Y | 1 |
| Zhang, Y | 1 |
| Trivedi, R | 1 |
| Gao, P | 1 |
| Senna, G | 1 |
| Caminati, M | 1 |
| Castells, M | 1 |
| Sharma, P | 2 |
| Yi, R | 1 |
| Nayak, AP | 1 |
| Wang, N | 1 |
| Tang, F | 1 |
| Knight, MJ | 1 |
| Pan, S | 1 |
| Oliver, B | 1 |
| Deshpande, DA | 2 |
| McAlinden, KD | 1 |
| Ghavami, S | 1 |
| Xenaki, D | 1 |
| Sohal, SS | 1 |
| Oliver, BG | 1 |
| Haghi, M | 1 |
| Sun, XC | 1 |
| Hu, XY | 1 |
| Wang, LJ | 1 |
| Liu, EM | 1 |
| Fu, Z | 1 |
| Zhu, MS | 1 |
| ENGESET, A | 1 |
| JUUL-MOLLER, O | 1 |
| BENDA, R | 1 |
| MOSSE, A | 1 |
| DE AGUILAR, R | 2 |
| AGARWAL, SL | 1 |
| DESHMANKAR, BS | 1 |
| BHARGAVA, V | 1 |
| ORINSTEIN, E | 1 |
| GEOFFROY, H | 1 |
| ALAMEL, P | 1 |
| BERRADA, A | 1 |
| DAOUDI, A | 1 |
| HIRAKI, H | 1 |
| KIMURA, I | 4 |
| MORIYA, K | 2 |
| TSUCHIDA, K | 1 |
| MATSUURA, Y | 2 |
| SHIBUYA, K | 1 |
| KOTANI, H | 1 |
| KRAMMER, H | 1 |
| MORITANI, Y | 1 |
| TSUCHIDA, J | 1 |
| MATSUURA, R | 1 |
| TIODA, J | 1 |
| Dean, T | 1 |
| Dewey, A | 1 |
| Bara, A | 1 |
| Lasserson, TJ | 1 |
| Walters, EH | 1 |
| Insanov, AB | 1 |
| Mustafaeva, LI | 1 |
| Mandour, AM | 1 |
| Omran, LA | 1 |
| Karapata, AP | 1 |
| Yan, GT | 1 |
| Rudyk, BI | 1 |
| Ayitey-Smith, E | 1 |
| Boye, GL | 1 |
| Furkert, K | 1 |
| Aviado, DM | 1 |
| Sadavongvivad, C | 1 |
| Cambar, P | 1 |
| Jäger, L | 1 |
| Pecherek, K | 1 |
| Sadowski, M | 1 |
| Narasaki, N | 1 |
| Suematsu, T | 1 |
| Ciszek, J | 2 |
| Walczak, J | 2 |
| Voog, R | 1 |
| Chouteau, J | 1 |
| Marchal, A | 1 |
| Cabanel, G | 1 |
| Isomaki, H | 1 |
| Kreus, KE | 1 |
| Jirkal, J | 1 |
| Salavec, M | 1 |
| Tennenbaum, JI | 1 |
| Smith, RE | 1 |
| Moriya, Y | 1 |
| Nishizaki, Y | 1 |
| Kudriavtsev, GV | 1 |
3 reviews available for chloroquine and Asthma
| Article | Year |
|---|---|
Chloroquine as a steroid sparing agent for asthma.
Topics: Adrenal Cortex Hormones; Asthma; Chloroquine; Humans; Hydroxychloroquine; Randomized Controlled Tria | 2003 |
[Antiasthmatics. 12].
Topics: Adrenal Cortex Hormones; Aminophylline; Anti-Bacterial Agents; Asthma; Atropine; Barbiturates; Bronc | 1967 |
[Progress in the symptomatic treatment of bronchial asthma].
Topics: Adrenergic beta-Agonists; Aerosols; Animals; Antimalarials; Asthma; Chloroquine; Diethylcarbamazine; | 1972 |
1 trial available for chloroquine and Asthma
| Article | Year |
|---|---|
Chloroquine in the treatment of bronchial asthma.
Topics: Adolescent; Adult; Aged; Asthma; Child; Chloroquine; Eye Diseases; Female; Humans; Male; Middle Aged | 1968 |
34 other studies available for chloroquine and Asthma
| Article | Year |
|---|---|
Type II alveolar epithelial cell aryl hydrocarbon receptor protects against allergic airway inflammation through controlling cell autophagy.
Topics: Allergens; Alveolar Epithelial Cells; Animals; Asthma; Autophagy; Basic Helix-Loop-Helix Transcripti | 2022 |
Editorial: Reconsidering anaphylaxis at the time of COVID-19 pandemic.
Topics: Adolescent; Adult; Anaphylaxis; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, | 2020 |
Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Flu | 2017 |
Autophagy Activation in Asthma Airways Remodeling.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthm | 2019 |
[Inhibitory effect of chloroquine on airway hyperresponsiveness in asthmatic mice].
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Chloroquine; Dexamethasone; Dinoprost; Disease Models | 2015 |
A "bitter" end to asthma revealed.
Topics: Adrenergic beta-2 Receptor Agonists; Anti-Inflammatory Agents; Asthma; Chloroquine; Humans; Myocytes | 2011 |
[Quinacrine & chloroquine in asthma therapy].
Topics: Asthma; Chloroquine; Disease; Peritoneal Diseases; Peritoneum; Quinacrine | 1957 |
[Bronchial asthma treated with chloroquine].
Topics: Asthma; Chloroquine | 1961 |
[Synthetic antimalarials in the treatment of asthma].
Topics: Antimalarials; Asthma; Chloroquine | 1962 |
[Preliminary considerations on a new treatment for infantile asthma. Hypotelencephaly of growth].
Topics: Asthma; Biological Phenomena; Child; Chloroquine; Humans; Infant; Physiological Phenomena | 1961 |
[Treatment of infantile asthma with chloroquine].
Topics: Asthma; Child; Chloroquine; Humans; Infant | 1962 |
CHLOROQUINE IN BRONCHIAL ASTHMA.
Topics: Asthma; Chloroquine; Histamine Release; Lung; Pharmacology; Rats; Research; Stomach | 1963 |
[PROTECTIVE SERUMS IN COMBINATION WITH CORTICOIDS AND GAMMA GLOBULINS].
Topics: Adrenal Cortex Hormones; Anti-Allergic Agents; Asthma; Chloroquine; gamma-Globulins; Histamine; Hist | 1963 |
[A CASE OF HIGHLY EVOLUTIVE AND CACHEXIA-CAUSING POLYNEURITIC FORM OF PERIARTERITIS NODOSA].
Topics: Asthma; Biopsy; Blood Chemical Analysis; Cachexia; Chloroquine; Eosinophilia; Fundus Oculi; Gastroen | 1963 |
[LECTURES ON NEW METHODS OF TREATING BRONCHIAL ASTHMA, WITH SPECIAL REFERENCE TO THE PROLONGED ADMINISTRATION OF CHLOROQUINE PHOSPHATE. (2)].
Topics: Adolescent; Asthma; Child; Chloroquine; Humans; Japan; Statistics as Topic | 1964 |
[Asthma therapy with resochin].
Topics: Asthma; Chloroquine | 1960 |
[Prolonged quinoline derivative (chloroquine) therapy of bronchial asthma].
Topics: Asthma; Chloroquine; Quinolines | 1962 |
[Studies on bronchial asthma therapy using quinoline derivatives. On results of orotic acid-chloroquine therapy].
Topics: Anti-Infective Agents, Local; Asthma; Chloroquine; Dermatologic Agents; Hydroxychloroquine; Hydroxyq | 1961 |
[Insanovin aerosol therapy in the treatment of bronchial asthma].
Topics: Adult; Aerosols; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchod | 2004 |
An authentic case of pulmonary malaria caused by Plasmodium falciparum.
Topics: Adult; Anemia; Asthma; Chloroquine; Humans; Malaria; Male; Plasmodium falciparum | 1981 |
[Ambulatory treatment of bronchial asthma patients with immunosuppressive agensts].
Topics: Adult; Ambulatory Care; Asthma; Chloroquine; Female; Humans; Immunosuppressive Agents; Male | 1977 |
[Changes in activity of phospholipase A2 and its metabolic production of prostaglandins in lung tissue of asthmatic guinea pigs].
Topics: 6-Ketoprostaglandin F1 alpha; Albumins; Animals; Asthma; Chloroquine; Dinoprost; Dinoprostone; Guine | 1992 |
[Comparative evaluation of various methods of immunosuppressive therapy in severe bronchial asthma].
Topics: Adolescent; Adult; Aged; Aminocaproic Acid; Asthma; Autoimmune Diseases; Azathioprine; Chloroquine; | 1985 |
Effect of chloroquine on histamine-induced bronchial asthma in the guinea-pig.
Topics: Animals; Asthma; Chloroquine; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Lung; Male | 1974 |
Cardiopulmonary effects of antimalarial drugs. 1. 4-Aminoquinolines: chloroquine quinetholate.
Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Asthma; Blood Pressure; Chloroform; Chloroquine; Dopamin | 1970 |
[Chloroquine in treatment of asthma in children].
Topics: Adolescent; Age Factors; Asthma; Child; Child, Preschool; Chloroquine; Female; Humans; Male; Optic N | 1973 |
[Therapy of bronchial asthma].
Topics: Adolescent; Adult; Aged; Allergens; Asthma; Child; Chloroquine; Desensitization, Immunologic; Dust; | 1971 |
Treatment of bronchial asthma with chloroquine.
Topics: Administration, Oral; Adult; Asthma; Chloroquine; Dexamethasone; Drug Tolerance; Female; Humans; Mal | 1971 |
[Asthma therapy with a combination of synthetic antimalarials (83 cases)].
Topics: Adolescent; Adult; Aged; Asthma; Chloroquine; Drug Synergism; Electrocardiography; Eosinophilia; Eye | 1969 |
[Treatment of bronchial asthma with arechin].
Topics: Acute Disease; Adult; Asthma; Chloroquine; Dexamethasone; Drug Synergism; Drug Tolerance; Female; Hu | 1970 |
[Antimalarials in the treatment of bronchial asthma].
Topics: Adolescent; Adult; Aged; Antimalarials; Asthma; Chloroquine; Female; Humans; Hypersensitivity; Infec | 1968 |
Antimalarial therapy for resistant asthma.
Topics: Adult; Asthma; Chloroquine; Female; Humans | 1966 |
[Study on allergens of bronchial asthma].
Topics: Adolescent; Adult; Aged; Allergens; Asthma; Child; Child, Preschool; Chloroquine; Female; Humans; Ma | 1966 |
[On the treatment of bronchial asthma with resoquine and delagyl in view of remote results].
Topics: Adult; Aged; Asthma; Chloroquine; Female; Humans; Male; Middle Aged | 1966 |