Page last updated: 2024-10-24

chloroquine and Arrhythmia

chloroquine has been researched along with Arrhythmia in 48 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Research Excerpts

ExcerptRelevanceReference
" Therefore, the aim of study was to evaluate the influence of seven-month chloroquine treatment with a 250mg daily dose on arrhythmia, conduction disturbances as well as heart rate variability and repolarization parameters assessed in 24-hour Holter monitoring."7.73The cardiac safety of chloroquine phosphate treatment in patients with systemic lupus erythematosus: the influence on arrhythmia, heart rate variability and repolarization parameters. ( Chudzik, M; Cygankiewicz, I; Sysa-Jedrzejowska, A; Wozniacka, A; Wranicz, JK, 2006)
"Chloroquine poisoning in children, although infrequent, is extremely dangerous because of the narrow margin between therapeutic and toxic doses."7.68Chloroquine poisoning in a child. ( Bernard, WD; Kelly, JC; Knapp, J; Schultz, C; Wasserman, GS, 1990)
" In fact, two of the actually used drugs against SARS-CoV2, such as chloroquine and the combination lopinavir/ritonavir, might determine a QT (the time from the start of the Q wave to the end of the T wave) interval prolongation and they show several interactions with antiarrhythmic drugs and antipsychotic medications, making them prone to an increased risk of developing arrhythmias."5.12COVID-19 and the burning issue of drug interaction: never forget the ECG. ( Cameli, M; Cameli, P; Franchi, F; Mandoli, GE; Menci, D; Mondillo, S; Sciaccaluga, C; Sisti, N; Valente, S, 2021)
"A 58 year old woman on long term treatment with chloroquine for systemic lupus erythematosus presented with cardiac conduction disorders and heart failure with hypertrophic cardiomyopathy, which was confirmed by histology to be related to chloroquine toxicity."4.80Chloroquine cardiomyopathy with conduction disorders. ( Baguet, JP; Fabre, M; Tremel, F, 1999)
"We applied a set of in silico and in vitro assays, compliant with the Comprehensive In Vitro Proarrhythmia Assay (CiPA) paradigm, to assess the risk of chloroquine (CLQ) or hydroxychloroquine (OH-CLQ)-mediated QT prolongation and Torsades de Pointes (TdP), alone and combined with erythromycin (ERT) and azithromycin (AZI), drugs repurposed during the first wave of coronavirus disease 2019 (COVID-19)."4.02Applying the CiPA approach to evaluate cardiac proarrhythmia risk of some antimalarials used off-label in the first wave of COVID-19. ( Abernathy, M; Anderson, WD; Beattie, KA; Chaudhary, KW; Coulot, J; Delaunois, A; Gryshkova, V; Hebeisen, S; Holbrook, M; Kramer, J; Kuryshev, Y; Leishman, D; Lushbough, I; Passini, E; Redfern, WS; Rodriguez, B; Rossman, EI; Trovato, C; Valentin, JP; Wu, C, 2021)
"Neither diazepam nor other ligands for benzodiazepine binding sites protect against or attenuate chloroquine cardiotoxicity."3.96Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam. ( Hughes, DA, 2020)
"Chloroquine seems to play a protective role in the unexpected high rate of cardiac arrhythmias and conduction disturbances observed in SLE."3.80Evidence for cardiac safety and antiarrhythmic potential of chloroquine in systemic lupus erythematosus. ( Bonfá, E; Borba, EF; Kalil-Filho, R; Martinelli Filho, M; Nishioka, S; Pedrosa, A; Ramires, JA; Teixeira, RA; Viana, VS, 2014)
" Therefore, the aim of study was to evaluate the influence of seven-month chloroquine treatment with a 250mg daily dose on arrhythmia, conduction disturbances as well as heart rate variability and repolarization parameters assessed in 24-hour Holter monitoring."3.73The cardiac safety of chloroquine phosphate treatment in patients with systemic lupus erythematosus: the influence on arrhythmia, heart rate variability and repolarization parameters. ( Chudzik, M; Cygankiewicz, I; Sysa-Jedrzejowska, A; Wozniacka, A; Wranicz, JK, 2006)
"Chloroquine poisoning in children, although infrequent, is extremely dangerous because of the narrow margin between therapeutic and toxic doses."3.68Chloroquine poisoning in a child. ( Bernard, WD; Kelly, JC; Knapp, J; Schultz, C; Wasserman, GS, 1990)
" However, some of these medications have potential cardiac adverse effects."2.66Cardiac safety of off-label COVID-19 drug therapy: a review and proposed monitoring protocol. ( Lazar, S; Naksuk, N; Peeraphatdit, TB, 2020)
"In the largest reported cohort of coronavirus disease 2019 patients to date treated with chloroquine/hydroxychloroquine±azithromycin, no instances of Torsade de pointes, or arrhythmogenic death were reported."1.56Effect of Chloroquine, Hydroxychloroquine, and Azithromycin on the Corrected QT Interval in Patients With SARS-CoV-2 Infection. ( Beldner, S; Chang, D; Chinitz, J; Epstein, LM; Gabriels, J; Goldner, B; Ismail, H; John, R; Mahmood, E; Makker, P; Mansoor, A; Mitra, R; Mountantonakis, S; Saleh, M; Skipitaris, N; Soo Kim, B; Willner, J, 2020)
"Due to potential arrhythmia risk from observed QT prolongation, alternans was assessed in the anesthetized guinea pig after azithromycin or chloroquine alone and after combination treatment at clinically relevant concentrations proposed for the management of malaria."1.34Azithromycin/chloroquine combination does not increase cardiac instability despite an increase in monophasic action potential duration in the anesthetized guinea pig. ( Deng, S; Duncan, JN; Dunne, M; Fossa, AA; Wisialowski, T, 2007)
"Life-threatening cardiac arrhythmias may be the first sign of overdosage."1.26Intentional chloroquine overdosage. ( Britton, WJ; Kevau, IH, 1978)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199020 (41.67)18.7374
1990's2 (4.17)18.2507
2000's3 (6.25)29.6817
2010's4 (8.33)24.3611
2020's19 (39.58)2.80

Authors

AuthorsStudies
Thomet, U1
Amuzescu, B1
Knott, T1
Mann, SA1
Mubagwa, K1
Radu, BM1
Souza-Silva, MVR1
Pereira, DN1
Pires, MC1
Vasconcelos, IM1
Schwarzbold, AV1
Vasconcelos, DH1
Pereira, EC1
Manenti, ERF1
Costa, FR1
Aguiar, FC1
Anschau, F1
Bartolazzi, F1
Nascimento, GF1
Vianna, HR1
Batista, JDL1
Machado-Rugolo, J1
Ruschel, KB1
Ferreira, MAP1
Oliveira, LS1
Menezes, LSM1
Ziegelmann, PK1
Tofani, MGT1
Bicalho, MAC1
Nogueira, MCA1
Guimarães-Júnior, MH1
Aguiar, RLO1
Rios, DRA1
Polanczyk, CA1
Marcolino, MS1
Juurlink, DN1
Lentini, G1
Cavalluzzi, MM1
Habtemariam, S1
Saleh, M1
Gabriels, J1
Chang, D1
Soo Kim, B1
Mansoor, A1
Mahmood, E1
Makker, P1
Ismail, H1
Goldner, B1
Willner, J1
Beldner, S1
Mitra, R1
John, R1
Chinitz, J1
Skipitaris, N1
Mountantonakis, S1
Epstein, LM1
Monzani, A1
Genoni, G1
Scopinaro, A1
Pistis, G1
Kozel, D1
Secco, GG1
Naksuk, N1
Lazar, S1
Peeraphatdit, TB1
Hughes, DA1
Asensio, E1
Acunzo, R1
Uribe, W1
Saad, EB1
Sáenz, LC1
Medeiros-Domingo, A1
Carrasco, OF1
Berni-Betancourt, A1
Norinder, U1
Tuck, A1
Norgren, K1
Munic Kos, V1
Sciaccaluga, C1
Cameli, M1
Menci, D1
Mandoli, GE1
Sisti, N1
Cameli, P1
Franchi, F1
Mondillo, S1
Valente, S1
Kim, YS1
Lee, SY1
Yoon, JW1
Kim, D1
Yu, S1
Kim, JS1
Kim, JH1
Varshneya, M1
Irurzun-Arana, I1
Campana, C1
Dariolli, R1
Gutierrez, A1
Pullinger, TK1
Sobie, EA1
Alkasir, A1
Lippmann, S1
Wong, AO1
Gurung, B1
Wong, WS1
Mak, SY1
Tse, WW1
Li, CM1
Lieu, DK1
Costa, KD1
Li, RA1
Hajjar, RJ1
Ehrlich, H1
Elkbuli, A1
Delaunois, A1
Abernathy, M1
Anderson, WD1
Beattie, KA1
Chaudhary, KW1
Coulot, J1
Gryshkova, V1
Hebeisen, S1
Holbrook, M1
Kramer, J1
Kuryshev, Y1
Leishman, D1
Lushbough, I1
Passini, E1
Redfern, WS1
Rodriguez, B1
Rossman, EI1
Trovato, C1
Wu, C1
Valentin, JP1
Ogah, OS1
Umuerri, EM1
Adebiyi, A1
Orimolade, OA1
Sani, MU1
Ojji, DB1
Mbakwem, AC1
Stewart, S1
Sliwa, K1
Luo, C1
Wang, K1
Liu, T1
Zhang, H2
Teixeira, RA1
Borba, EF1
Pedrosa, A1
Nishioka, S1
Viana, VS1
Ramires, JA1
Kalil-Filho, R1
Bonfá, E1
Martinelli Filho, M1
Karathanos, TV1
Boyle, PM1
Trayanova, NA1
El Harchi, A1
McPate, MJ1
Zhang, Yh1
Hancox, JC1
Phipps, C1
Chan, K1
Teo, F1
Ponampalam, R1
BURRELL, ZL1
MARTINEZ, AC1
YU, KJ2
HSU, CY2
HUANG, MH2
CH'EN, HM1
CHOU, CL1
BASSET, A1
MOINS, H1
ORTOLANI, G1
GIULIANI, V1
ELISEO, V1
SOKOLOV-PONOMAREVA, OD1
BEREZHKOV, LF1
SANABRIA, A1
CARBONELL, LM1
SOTO, R1
Wozniacka, A1
Cygankiewicz, I1
Chudzik, M1
Sysa-Jedrzejowska, A1
Wranicz, JK1
Fossa, AA1
Wisialowski, T1
Duncan, JN1
Deng, S1
Dunne, M1
Baguet, JP1
Tremel, F1
Fabre, M1
Mono, G1
Kuhn, E1
Swift, A1
Karmazyn, M1
Horrobin, DF1
Manku, MS1
Karmali, RA1
Morgan, RO1
Ally, AI1
Singh, A1
Singh, N1
Singh, J1
Britton, WJ1
Kevau, IH1
Charles, D1
Ducloux, M1
Descamps, DP1
Norman, P1
Kelly, JC1
Wasserman, GS1
Bernard, WD1
Schultz, C1
Knapp, J1
Jurik, AG1
Møller, P1
Sogani, RK1
Sharma, DK1
Gupta, V1
Alekseev, GK1
Aviado, DM1
Sadavongvivad, C1
Cambar, P1
Ayitey-Smith, E1
Boye, GL1
Nichani, N1
Lewis, RA1
Don Michael, TA1
Aiwazzadeh, S1
Sagardiluz, J1
Clèdes, J1
Potaux, L1
Favarel-Garrigues, JC1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Low-dose Hydroxychloroquine and Bromhexine: a Novel Regimen for COVID-19 Prophylaxis in Healthcare Professionals (ELEVATE Trial)[NCT04340349]Early Phase 1214 participants (Anticipated)Interventional2021-02-01Enrolling by invitation
Safety and Efficacy of Post-exposure Prophylaxis With Hydroxychloroquine (HCQ) for the Prevention of COVID-19 in High-risk Older Individuals in Long-term and Specialized Care: A Double-blind Randomized Control Trial[NCT04397328]Phase 3336 participants (Anticipated)Interventional2020-05-19Not yet recruiting
Chloroquine for Patients With Symptomatic Persistent Atrial Fibrillation: A Prospective Pilot Study[NCT02932007]Phase 240 participants (Anticipated)Interventional2017-03-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for chloroquine and Arrhythmia

ArticleYear
Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2020, Apr-27, Volume: 192, Issue:17

    Topics: Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infe

2020
Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2020, Apr-27, Volume: 192, Issue:17

    Topics: Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infe

2020
Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2020, Apr-27, Volume: 192, Issue:17

    Topics: Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infe

2020
Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2020, Apr-27, Volume: 192, Issue:17

    Topics: Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infe

2020
Cardiac safety of off-label COVID-19 drug therapy: a review and proposed monitoring protocol.
    European heart journal. Acute cardiovascular care, 2020, Volume: 9, Issue:3

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Antimalarials; Arrhythmias, Cardiac; Betacoronavirus;

2020
Recommendations for the measurement of the QT interval during the use of drugs for COVID-19 infection treatment. Updatable in accordance with the availability of new evidence.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2020, Volume: 59, Issue:2

    Topics: Adult; Aged; Antimalarials; Arrhythmias, Cardiac; Azithromycin; Chloroquine; Coronavirus Infections;

2020
Existing highly accumulating lysosomotropic drugs with potential for repurposing to target COVID-19.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 130

    Topics: Anti-Inflammatory Agents; Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Betacoronavirus; Che

2020
COVID-19 and the burning issue of drug interaction: never forget the ECG.
    Postgraduate medical journal, 2021, Volume: 97, Issue:1145

    Topics: Adenosine Monophosphate; Alanine; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Antiviral

2021
SARS-CoV 2 Infection (Covid-19) and Cardiovascular Disease in Africa: Health Care and Socio-Economic Implications.
    Global heart, 2021, 03-15, Volume: 16, Issue:1

    Topics: Acute Coronary Syndrome; Africa; Antimalarials; Arrhythmias, Cardiac; Cardiovascular Diseases; Chlor

2021
Chloroquine cardiomyopathy with conduction disorders.
    Heart (British Cardiac Society), 1999, Volume: 81, Issue:2

    Topics: Antirheumatic Agents; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Chloroquine; Echocardiogra

1999
[Cardiotoxic effects of drugs and various other substances. A review].
    Fortschritte der Medizin, 1978, Apr-13, Volume: 96, Issue:14

    Topics: Adrenergic Agonists; Amphetamine; Antimony; Arrhythmias, Cardiac; Arsenic Poisoning; Catecholamines;

1978

Other Studies

40 other studies available for chloroquine and Arrhythmia

ArticleYear
Assessment of proarrhythmogenic risk for chloroquine and hydroxychloroquine using the CiPA concept.
    European journal of pharmacology, 2021, Dec-15, Volume: 913

    Topics: Action Potentials; Antiviral Agents; Arrhythmias, Cardiac; Biological Assay; Chloroquine; Computer S

2021
Real-Life Data on Hydroxychloroquine or Chloroquine with or Without Azithromycin in COVID-19 Patients: A Retrospective Analysis in Brazil.
    Arquivos brasileiros de cardiologia, 2023, Volume: 120, Issue:9

    Topics: Aged; Arrhythmias, Cardiac; Azithromycin; Brazil; Chloroquine; Cohort Studies; COVID-19; COVID-19 Dr

2023
COVID-19, Chloroquine Repurposing, and Cardiac Safety Concern: Chirality Might Help.
    Molecules (Basel, Switzerland), 2020, Apr-16, Volume: 25, Issue:8

    Topics: Antimalarials; Antiviral Agents; Arrhythmias, Cardiac; Betacoronavirus; Cardiotoxicity; Chloroquine;

2020
Effect of Chloroquine, Hydroxychloroquine, and Azithromycin on the Corrected QT Interval in Patients With SARS-CoV-2 Infection.
    Circulation. Arrhythmia and electrophysiology, 2020, Volume: 13, Issue:6

    Topics: Anti-Bacterial Agents; Antimalarials; Arrhythmias, Cardiac; Azithromycin; Betacoronavirus; Chloroqui

2020
QTc evaluation in COVID-19 patients treated with chloroquine/hydroxychloroquine.
    European journal of clinical investigation, 2020, Volume: 50, Issue:6

    Topics: Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Cardiotoxicity; Chloroquine; Coronavirus Infec

2020
Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam.
    British journal of pharmacology, 2020, Volume: 177, Issue:21

    Topics: Animals; Arrhythmias, Cardiac; Benzodiazepinones; Cardiotoxicity; Chloroquine; Clonazepam; Coronavir

2020
Potential pro-arrhythmic effects of pharmacotherapy against SARS-CoV-2.
    Archivos de cardiologia de Mexico, 2020, Volume: 90, Issue:Supl

    Topics: Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Chloroquine; Coronavirus Infections; COVID-19;

2020
Cardiotoxicity induced by the combination therapy of chloroquine and azithromycin in human embryonic stem cell-derived cardiomyocytes.
    BMB reports, 2020, Volume: 53, Issue:10

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Azithromycin; Cardiotoxicity; Cell Differentiation

2020
Investigational Treatments for COVID-19 may Increase Ventricular Arrhythmia Risk Through Drug Interactions.
    CPT: pharmacometrics & systems pharmacology, 2021, Volume: 10, Issue:2

    Topics: Action Potentials; Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Chloroquine; COVID-19; COVI

2021
COVID-19 and Cardiac Concerns for Psychiatric Patients.
    The primary care companion for CNS disorders, 2020, 12-03, Volume: 22, Issue:6

    Topics: Antidepressive Agents; Antiviral Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrioventricular

2020
Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues.
    Journal of molecular and cellular cardiology, 2021, Volume: 153

    Topics: Anti-Bacterial Agents; Antimalarials; Arrhythmias, Cardiac; Azithromycin; Chloroquine; COVID-19 Drug

2021
Cardiac arrhythmias in COVID-19 patients: A combination of viral comorbidities and pro-arrhythmic drug interactions.
    The American journal of emergency medicine, 2021, Volume: 48

    Topics: Angiotensin-Converting Enzyme 2; Anti-Bacterial Agents; Antimalarials; Arrhythmias, Cardiac; Azithro

2021
Applying the CiPA approach to evaluate cardiac proarrhythmia risk of some antimalarials used off-label in the first wave of COVID-19.
    Clinical and translational science, 2021, Volume: 14, Issue:3

    Topics: Animals; Antimalarials; Arrhythmias, Cardiac; Chloroquine; CHO Cells; COVID-19 Drug Treatment; Crice

2021
Computational Analysis of the Action of Chloroquine on Short QT Syndrome Variant 1 and Variant 3 in Human Ventricles.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2018, Volume: 2018

    Topics: Action Potentials; Arrhythmias, Cardiac; Chloroquine; Electrocardiography; Heart Conduction System;

2018
Evidence for cardiac safety and antiarrhythmic potential of chloroquine in systemic lupus erythematosus.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2014, Volume: 16, Issue:6

    Topics: Adult; Anti-Arrhythmia Agents; Antirheumatic Agents; Arrhythmias, Cardiac; Brazil; Cardiotonic Agent

2014
Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2014, Volume: 16 Suppl 4

    Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chloroquine; Computer Simulation; E

2014
Action potential clamp and chloroquine sensitivity of mutant Kir2.1 channels responsible for variant 3 short QT syndrome.
    Journal of molecular and cellular cardiology, 2009, Volume: 47, Issue:5

    Topics: Action Potentials; Animals; Antirheumatic Agents; Arrhythmias, Cardiac; Chloroquine; CHO Cells; Cric

2009
Fatal chloroquine poisoning: a rare cause of sudden cardiac arrest.
    Annals of the Academy of Medicine, Singapore, 2011, Volume: 40, Issue:6

    Topics: Acute Disease; Adult; Antimalarials; Arrhythmias, Cardiac; Chloroquine; Death, Sudden, Cardiac; Drug

2011
Chloroquine and hydroxychloroquine in the treatment of cardiac arrhythmias.
    The New England journal of medicine, 1958, Apr-17, Volume: 258, Issue:16

    Topics: Arrhythmias, Cardiac; Chloroquine; Humans; Hydroxychloroquine

1958
[Therapeutic effect of chloroquine on cardiac arrhythmias].
    Zhonghua nei ke za zhi, 1959, Volume: 7, Issue:2

    Topics: Arrhythmias, Cardiac; Chloroquine; Humans

1959
Chloroquine in treatment of cardiac arrhythmias: a preliminary report.
    Chinese medical journal (Peking, China : 1932), 1959, Volume: 78

    Topics: Arrhythmias, Cardiac; Chloroquine

1959
Clinical assessment of therapeutic effects of chloroquine on cardiac arrhythmias.
    Chinese medical journal (Peking, China : 1932), 1960, Volume: 80

    Topics: Arrhythmias, Cardiac; Chloroquine

1960
[Reduction of complete arrhythmia by chloroquine].
    Archives des maladies du coeur et des vaisseaux, 1961, Volume: 54

    Topics: Arrhythmias, Cardiac; Chloroquine; Humans

1961
[Chloroquine and hydroxychloroquine in the therapy of arrhythmia due to fibrillation].
    La Riforma medica, 1963, Mar-02, Volume: 77

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Chloroquine; Heart Conduc

1963
[SOME NEW DRUGS IN THE TREATMENT OF RHEUMATIC CHILDREN].
    Pediatriia, 1964, Volume: 43

    Topics: Adolescent; Alkaloids; Anabolic Agents; Antithyroid Agents; Arrhythmias, Cardiac; Cardiovascular Dis

1964
Action of procainamide, quinidine and chloroquine upon the conduction system of the dog's heart (histochemical study).
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1959, Volume: 7

    Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Chloroquine; Dog

1959
The cardiac safety of chloroquine phosphate treatment in patients with systemic lupus erythematosus: the influence on arrhythmia, heart rate variability and repolarization parameters.
    Lupus, 2006, Volume: 15, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arrhythmias, Cardiac; Chloroquine; El

2006
Azithromycin/chloroquine combination does not increase cardiac instability despite an increase in monophasic action potential duration in the anesthetized guinea pig.
    The American journal of tropical medicine and hygiene, 2007, Volume: 77, Issue:5

    Topics: Action Potentials; Anesthesia; Animals; Antimalarials; Arrhythmias, Cardiac; Azithromycin; Blood Pre

2007
Low prostaglandin concentrations cause cardiac rhythm disturbances. Effect reversed by low levels of copper or chloroquine.
    Prostaglandins, 1978, Volume: 15, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Chloroquine; Copper; Drug Synergism; Heart Conduction System; Indomet

1978
Oral chloroquine therapy in premature beats.
    Journal of the Indian Medical Association, 1978, Mar-16, Volume: 70, Issue:6

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Chloroquine; Female; Humans; Male; Middle Aged

1978
Intentional chloroquine overdosage.
    The Medical journal of Australia, 1978, Oct-21, Volume: 2, Issue:9

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Chloroquine; Electrocardiography; Female; Heart; Humans; Ma

1978
[The heart in severe chloroquine poisoning. Apropos of 4 cases].
    Bulletin de la Societe medicale d'Afrique noire de langue francaise, 1975, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Chloroquine; Female; Heart; Heart Conduction System; Humans

1975
Chloroquine poisoning in a child.
    Annals of emergency medicine, 1990, Volume: 19, Issue:1

    Topics: Apnea; Arrhythmias, Cardiac; Chloroquine; Female; Humans; Infant; Poisoning; Seizures

1990
Atrioventricular conduction time in rheumatoid arthritis.
    Rheumatology international, 1985, Volume: 5, Issue:5

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Arthritis, Rheumatoid; Atrioventricular Node; Cardiom

1985
Cardiovascular collapse following small dose of chloroquin in healthy young adult.
    The Journal of the Association of Physicians of India, 1986, Volume: 34, Issue:7

    Topics: Adult; Arrhythmias, Cardiac; Chloroquine; Humans; Male

1986
[Observations on the treatment of certain forms of arrhythmia using contemporary methods].
    Kardiologiia, 1968, Volume: 8, Issue:1

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Card

1968
Cardiopulmonary effects of antimalarial drugs. 1. 4-Aminoquinolines: chloroquine quinetholate.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:1

    Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Asthma; Blood Pressure; Chloroform; Chloroquine; Dopamin

1970
Effect of hyperthermia on acute chloroquine toxicity in rabbits.
    European journal of pharmacology, 1974, Volume: 25, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Chloroquine; Electrocardiography; Female; Fever; Male

1974
The effects of acute chloroquine poisoning with special reference to the heart.
    American heart journal, 1970, Volume: 79, Issue:6

    Topics: Adolescent; Animals; Antidotes; Arrhythmias, Cardiac; Bradycardia; Chloroquine; Dogs; Epinephrine; H

1970
[Cardiac complications in acute poisoning].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1967, Volume: 144, Issue:7

    Topics: Adolescent; Adult; Amitriptyline; Arrhythmias, Cardiac; Child; Child, Preschool; Chloroquine; Digita

1967