chloroquine has been researched along with Apoplexy in 3 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine treatment prevented ganglioside dysregulation 3 days post-stroke and partially prevented complex ganglioside depletion 21 days post-stroke." | 5.51 | Chloroquine Restores Ganglioside Homeostasis and Improves Pathological and Behavioral Outcomes Post-stroke in the Rat. ( Caughlin, S; Cechetto, DF; Hepburn, J; Liu, Q; Wang, L; Whitehead, SN; Yeung, KK, 2019) |
| "Chloroquine pretreatment significantly enhanced rats' short-term spatial memory capacity and attenuated the expression of TLR3, IFR3, and IFN-β in the Hippocampus compared to non-treatment control in tGCI rats." | 5.39 | Chloroquine pretreatment inhibits toll-like receptor 3 signaling after stroke. ( Chen, W; Cui, G; Hua, F; Ye, X; Zhao, H; Zhao, Q; Zuo, T, 2013) |
| "Chloroquine treatment prevented ganglioside dysregulation 3 days post-stroke and partially prevented complex ganglioside depletion 21 days post-stroke." | 1.51 | Chloroquine Restores Ganglioside Homeostasis and Improves Pathological and Behavioral Outcomes Post-stroke in the Rat. ( Caughlin, S; Cechetto, DF; Hepburn, J; Liu, Q; Wang, L; Whitehead, SN; Yeung, KK, 2019) |
| "Chloroquine pretreatment significantly enhanced rats' short-term spatial memory capacity and attenuated the expression of TLR3, IFR3, and IFN-β in the Hippocampus compared to non-treatment control in tGCI rats." | 1.39 | Chloroquine pretreatment inhibits toll-like receptor 3 signaling after stroke. ( Chen, W; Cui, G; Hua, F; Ye, X; Zhao, H; Zhao, Q; Zuo, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, YY | 1 |
| Zhang, TY | 1 |
| Xue, X | 1 |
| Liu, DM | 1 |
| Zhang, HT | 1 |
| Yuan, LL | 1 |
| Liu, YL | 1 |
| Yang, HL | 1 |
| Sun, SB | 1 |
| Zhang, C | 1 |
| Xu, HS | 1 |
| Wu, CF | 1 |
| Yang, JY | 1 |
| Caughlin, S | 1 |
| Hepburn, J | 1 |
| Liu, Q | 1 |
| Wang, L | 1 |
| Yeung, KK | 1 |
| Cechetto, DF | 1 |
| Whitehead, SN | 1 |
| Cui, G | 1 |
| Ye, X | 1 |
| Zuo, T | 1 |
| Zhao, H | 1 |
| Zhao, Q | 1 |
| Chen, W | 1 |
| Hua, F | 1 |
3 other studies available for chloroquine and Apoplexy
| Article | Year |
|---|---|
Pseudoginsenoside-F11 attenuates cerebral ischemic injury by alleviating autophagic/lysosomal defects.
Topics: Animals; Apoptosis; Autophagy; Brain; Brain Edema; Brain Ischemia; Chloroquine; Disease Models, Anim | 2017 |
Chloroquine Restores Ganglioside Homeostasis and Improves Pathological and Behavioral Outcomes Post-stroke in the Rat.
Topics: Animals; Behavior, Animal; Cell Survival; Cells, Cultured; Chloroquine; Forelimb; Gangliosides; Home | 2019 |
Chloroquine pretreatment inhibits toll-like receptor 3 signaling after stroke.
Topics: Animals; Chloroquine; Interferon Regulatory Factor-3; Interferon-beta; Male; Memory; Premedication; | 2013 |