chloroquine has been researched along with Anti-MuSK Myasthenia Gravis in 15 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine induced a myasthenic syndrome in a patient taking the drug for presumable reticular erythematous mucinosis." | 8.77 | Myasthenic syndrome caused by direct effect of chloroquine on neuromuscular junction. ( Bednarik, J; Bourgeois, P; Carton, H; Robberecht, W; van Hees, J, 1989) |
| "The anti-rheumatoid drug D-penicillamine (D-pen) has a reactive sulfhydryl group capable of modifying self antigens, and can provoke typical autoantibody-mediated myasthenia gravis (MG), especially in DR1+ individuals." | 7.70 | T cell responses to D-penicillamine in drug-induced myasthenia gravis: recognition of modified DR1:peptide complexes. ( Hill, M; Moss, P; Newsom-Davis, J; Willcox, N; Wordsworth, P, 1999) |
| "We have described a unique patient who had reversible and dose-related myasthenia gravis after penicillamine and chloroquine therapy for rheumatoid arthritis." | 7.67 | Myasthenia gravis caused by penicillamine and chloroquine therapy for rheumatoid arthritis. ( Hearn, J; Tiliakos, NA, 1986) |
| "Chloroquine induced a myasthenic syndrome in a patient taking the drug for presumable reticular erythematous mucinosis." | 4.77 | Myasthenic syndrome caused by direct effect of chloroquine on neuromuscular junction. ( Bednarik, J; Bourgeois, P; Carton, H; Robberecht, W; van Hees, J, 1989) |
| "The anti-rheumatoid drug D-penicillamine (D-pen) has a reactive sulfhydryl group capable of modifying self antigens, and can provoke typical autoantibody-mediated myasthenia gravis (MG), especially in DR1+ individuals." | 3.70 | T cell responses to D-penicillamine in drug-induced myasthenia gravis: recognition of modified DR1:peptide complexes. ( Hill, M; Moss, P; Newsom-Davis, J; Willcox, N; Wordsworth, P, 1999) |
| "A middle-age woman had intermittently had chloroquine as an antimalarial agent for 21 years." | 3.68 | Persisting chloroquine-induced myasthenia? ( De Bleecker, J; De Reuck, J; Meire, F; Quatacker, J, 1991) |
| "We have described a unique patient who had reversible and dose-related myasthenia gravis after penicillamine and chloroquine therapy for rheumatoid arthritis." | 3.67 | Myasthenia gravis caused by penicillamine and chloroquine therapy for rheumatoid arthritis. ( Hearn, J; Tiliakos, NA, 1986) |
| "Myasthenic reaction with partial neuromuscular block in the electromyogram and increased antibodies against acetylcholine-receptor protein developed during chloroquine administration over two months in a 52-year-old man known for eight years ot have rheumatoid arthritis." | 3.66 | [Myasthenia syndrome during chloroquine treatment (author's transl)]. ( Fateh-Moghadam, A; Schumm, F; Wiethölter, H, 1981) |
| "A young woman on chronic corticosteroid treatment for systemic lupus erythematosus developed a myasthenia-like syndrome 7 weeks after starting chloroquine therapy." | 1.27 | Chloroquine myopathy and myasthenia-like syndrome. ( Cornelio, F; Mantegazza, R; Mora, M; Pareyson, D; Sghirlanzoni, A, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Guidon, AC | 1 |
| Amato, AA | 1 |
| Killen, JA | 1 |
| Lindstrom, JM | 1 |
| Pichon, P | 1 |
| Soichot, P | 1 |
| Loche, D | 1 |
| Chapelon, M | 1 |
| Schumm, F | 1 |
| Wiethölter, H | 1 |
| Fateh-Moghadam, A | 1 |
| Savage, CO | 1 |
| Brooks, CJ | 1 |
| Harcourt, GC | 1 |
| Picard, JK | 1 |
| King, W | 1 |
| Sansom, DM | 1 |
| Willcox, N | 2 |
| Brüggemann, W | 1 |
| Herath, H | 1 |
| Ferbert, A | 1 |
| Hill, M | 1 |
| Moss, P | 1 |
| Wordsworth, P | 1 |
| Newsom-Davis, J | 1 |
| Argov, Z | 1 |
| Mastaglia, FL | 1 |
| De Bleecker, J | 1 |
| De Reuck, J | 1 |
| Quatacker, J | 1 |
| Meire, F | 1 |
| Robberecht, W | 1 |
| Bednarik, J | 1 |
| Bourgeois, P | 1 |
| van Hees, J | 1 |
| Carton, H | 1 |
| Muirden, KD | 1 |
| Sghirlanzoni, A | 1 |
| Mantegazza, R | 1 |
| Mora, M | 1 |
| Pareyson, D | 1 |
| Cornelio, F | 1 |
| Hearn, J | 1 |
| Tiliakos, NA | 1 |
| Thomas, PK | 1 |
| Oosterhuis, HJ | 1 |
| de Haas, WH | 1 |
4 reviews available for chloroquine and Anti-MuSK Myasthenia Gravis
| Article | Year |
|---|---|
COVID-19 and neuromuscular disorders.
Topics: Antiviral Agents; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Vaccines; Delivery of Heal | 2020 |
Drug therapy: Disorders of neuromuscular transmission caused by drugs.
Topics: Aged; Animals; Anti-Bacterial Agents; Anticonvulsants; Cardiovascular Agents; Chloroquine; Drug-Rela | 1979 |
Myasthenic syndrome caused by direct effect of chloroquine on neuromuscular junction.
Topics: Adult; Chloroquine; Electric Stimulation; Electromyography; Erythema; Female; Humans; Injections; Ma | 1989 |
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
1 trial available for chloroquine and Anti-MuSK Myasthenia Gravis
| Article | Year |
|---|---|
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
11 other studies available for chloroquine and Anti-MuSK Myasthenia Gravis
| Article | Year |
|---|---|
Specific killing of lymphocytes that cause experimental autoimmune myasthenia gravis by ricin toxin-acetylcholine receptor conjugates.
Topics: Adjuvants, Immunologic; Animals; Autoimmune Diseases; B-Lymphocytes; Chloroquine; Cytotoxins; Lympho | 1984 |
[Myasthenic syndrome induced by chloroquine poisoning: an unusual clinical form confirmed by ocular involvement].
Topics: Adult; Chloroquine; Electromyography; Eye Diseases; Humans; Male; Myasthenia Gravis | 1984 |
[Myasthenia syndrome during chloroquine treatment (author's transl)].
Topics: Arthritis, Rheumatoid; Chloroquine; Electromyography; Humans; Male; Middle Aged; Myasthenia Gravis | 1981 |
Human vascular endothelial cells process and present autoantigen to human T cell lines.
Topics: Antigen Presentation; Antigens, CD; Autoantigens; B7-1 Antigen; CD28 Antigens; CD58 Antigens; Cell A | 1995 |
[Follow-up and immunologic findings in drug-induced myasthenia].
Topics: Aged; Antirheumatic Agents; Autoantibodies; Chloroquine; Female; Follow-Up Studies; HLA-DR4 Antigen; | 1996 |
T cell responses to D-penicillamine in drug-induced myasthenia gravis: recognition of modified DR1:peptide complexes.
Topics: Aged; Amino Acid Sequence; Antirheumatic Agents; Autoimmune Diseases; Base Sequence; Blood Proteins; | 1999 |
Persisting chloroquine-induced myasthenia?
Topics: Chloroquine; Edrophonium; Female; Humans; Malaria; Middle Aged; Muscles; Myasthenia Gravis | 1991 |
Chloroquine myopathy and myasthenia-like syndrome.
Topics: Adult; Biopsy; Chloroquine; Female; Humans; Lupus Erythematosus, Systemic; Microscopy, Electron; Mus | 1988 |
Myasthenia gravis caused by penicillamine and chloroquine therapy for rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Chloroquine; Dose-Response Relationship, Drug; Humans; Male; Myastheni | 1986 |
Myopathy.
Topics: Alcoholism; Chloroquine; Glucosyltransferases; Glycogen Storage Disease; Humans; Ischemia; Muscular | 1970 |
Curare sensitivity and myastheniform symptoms in patients with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Blepharoptosis; Chloroquine; Diplopia; Eye Manifestations; Female; Huma | 1969 |