Page last updated: 2024-10-24

chloroquine and Anemia, Hemolytic

chloroquine has been researched along with Anemia, Hemolytic in 25 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).

Research Excerpts

ExcerptRelevanceReference
"Primaquine has the potential to reduce malaria-related anaemia at day 42 and beyond by preventing recurrent parasitaemia."6.61The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis. ( Abreha, T; Alemu, SG; Añez, A; Anstey, NM; Aseffa, A; Assefa, A; Awab, GR; Baird, JK; Barber, BE; Borghini-Fuhrer, I; Chu, CS; Commons, RJ; D'Alessandro, U; Dahal, P; Daher, A; de Vries, PJ; Douglas, NM; Erhart, A; Gomes, MSM; Grigg, MJ; Guerin, PJ; Hien, TT; Hwang, J; Kager, PA; Ketema, T; Khan, WA; Lacerda, MVG; Leslie, T; Ley, B; Lidia, K; Monteiro, WM; Nosten, F; Pereira, DB; Phan, GT; Phyo, AP; Price, RN; Rowland, M; Saravu, K; Sibley, CH; Simpson, JA; Siqueira, AM; Stepniewska, K; Taylor, WRJ; Thriemer, K; Thwaites, G; Tran, BQ; Vieira, JLF; Wangchuk, S; Watson, J; White, NJ; William, T; Woodrow, CJ, 2019)
"Chloroquine, quinine, quinacrine and related drugs are effective antimalarial agents only against parasites that degrade haemoglobin."3.66Mode of action of antimalarial drugs. ( Fitch, CD, 1983)
"Primaquine has the potential to reduce malaria-related anaemia at day 42 and beyond by preventing recurrent parasitaemia."2.61The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis. ( Abreha, T; Alemu, SG; Añez, A; Anstey, NM; Aseffa, A; Assefa, A; Awab, GR; Baird, JK; Barber, BE; Borghini-Fuhrer, I; Chu, CS; Commons, RJ; D'Alessandro, U; Dahal, P; Daher, A; de Vries, PJ; Douglas, NM; Erhart, A; Gomes, MSM; Grigg, MJ; Guerin, PJ; Hien, TT; Hwang, J; Kager, PA; Ketema, T; Khan, WA; Lacerda, MVG; Leslie, T; Ley, B; Lidia, K; Monteiro, WM; Nosten, F; Pereira, DB; Phan, GT; Phyo, AP; Price, RN; Rowland, M; Saravu, K; Sibley, CH; Simpson, JA; Siqueira, AM; Stepniewska, K; Taylor, WRJ; Thriemer, K; Thwaites, G; Tran, BQ; Vieira, JLF; Wangchuk, S; Watson, J; White, NJ; William, T; Woodrow, CJ, 2019)
"Cases of human babesiosis are rarely reported and probably under-diagnosed in China; therefore, improving our understanding of this disease as a newly emerging public health threat is imperative."1.48Human babesiosis in Southeast China: A case report. ( Chen, H; Huang, S; Jin, L; Li, J; Ni, Q; Pan, C; Yao, L; Zhang, L, 2018)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199018 (72.00)18.7374
1990's0 (0.00)18.2507
2000's2 (8.00)29.6817
2010's4 (16.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Devine, A1
Howes, RE1
Price, DJ1
Moore, KA1
Ley, B2
Simpson, JA2
Dittrich, S1
Price, RN2
Huang, S1
Zhang, L1
Yao, L1
Li, J1
Chen, H1
Ni, Q1
Pan, C1
Jin, L1
Commons, RJ1
Thriemer, K1
Chu, CS1
Douglas, NM1
Abreha, T1
Alemu, SG1
Añez, A1
Anstey, NM1
Aseffa, A1
Assefa, A1
Awab, GR1
Baird, JK1
Barber, BE1
Borghini-Fuhrer, I1
D'Alessandro, U1
Dahal, P1
Daher, A1
de Vries, PJ1
Erhart, A1
Gomes, MSM1
Grigg, MJ1
Hwang, J1
Kager, PA1
Ketema, T1
Khan, WA1
Lacerda, MVG1
Leslie, T1
Lidia, K1
Monteiro, WM1
Pereira, DB1
Phan, GT1
Phyo, AP1
Rowland, M1
Saravu, K1
Sibley, CH1
Siqueira, AM1
Stepniewska, K1
Taylor, WRJ1
Thwaites, G1
Tran, BQ1
Hien, TT1
Vieira, JLF1
Wangchuk, S1
Watson, J1
William, T1
Woodrow, CJ1
Nosten, F1
Guerin, PJ1
White, NJ1
Zhang, P1
Gao, X1
Ishida, H1
Amnuaysirikul, J1
Weina, PJ1
Grogl, M1
O'Neil, MT1
Li, Q1
Caridha, D1
Ohrt, C2
Hickman, M1
Magill, AJ2
Ray, P1
Rochford, R1
Baresel, PC1
Campo, B1
Sampath, A1
Tekwani, BL1
Walker, LA1
WITTMER, JF1
KUPCHINSKAS, IuK1
Fitch, CD1
Flici, O1
Tadjerouni, A1
Leroy, F1
Teys, JP1
Hubinont, PO1
Khoo, KK1
Kedar, PS1
Ghosh, K1
Colah, RB1
Mohanty, D1
Buchachart, K1
Krudsood, S1
Singhasivanon, P1
Treeprasertsuk, S1
Phophak, N1
Srivilairit, S1
Chalermrut, K1
Rattanapong, Y1
Supeeranuntha, L1
Wilairatana, P1
Brittenham, G1
Looareesuwan, S1
Gnehm, HE1
Waldvogel, FA1
Berner, H1
Brown, GV1
Adner, MM1
Altstatt, LB1
Conrad, ME1
Anderson, AE1
Cassaday, PB1
Healy, GR1
Conte, J1
Durand, D1
Ton That, H1
Suc, JM1
Brewer, GJ1
Zarafonetis, CJ1
Sheehy, TW1
Reba, RC1
Parks, GR1
Martelo, OJ1
Smoller, M1
Saladin, TA1
Nkrumah, FK1
Rey, M1
Camerlynck, P1
Oudart, JL1
Zucker, JM1
Plassart, M1
Alihonou, E1
Lafaix, C1
Stevenson, DD1
McGerity, JL1
Pannacciulli, I1
Salvidio, E1
Tizianello, A1
Parravidino, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does Artemisinin Combination Treatment Reduce the Radical Curative Efficacy of High Dose Tafenoquine for Plasmodium Vivax Malaria?[NCT05788094]Phase 4388 participants (Anticipated)Interventional2023-06-26Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for chloroquine and Anemia, Hemolytic

ArticleYear
The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis.
    BMC medicine, 2019, 08-01, Volume: 17, Issue:1

    Topics: Adult; Anemia, Hemolytic; Antimalarials; Chloroquine; Female; Glucosephosphate Dehydrogenase Deficie

2019
[AUTOALLERGY IN CLINICAL INTERNAL MEDICINE].
    Klinicheskaia meditsina, 1964, Volume: 42

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Agranulocytosis; Anemia, Hemolytic; Anemia, He

1964
[Malaria in pregnant women. Presentation of 2 cases and review of the literature].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1982, Volume: 11, Issue:8

    Topics: Abortion, Spontaneous; Acute Kidney Injury; Adult; Anemia, Hemolytic; Antimalarials; Brain Diseases;

1982
Chemoprophylaxis of malaria.
    The Medical journal of Australia, 1986, Jun-23, Volume: 144, Issue:13

    Topics: Adolescent; Adult; Africa; Anemia, Hemolytic; Asia; Australia; Child; Child, Preschool; Chloroquine;

1986

Trials

2 trials available for chloroquine and Anemia, Hemolytic

ArticleYear
The treatment of malaria in glucose-6-phosphate dehydrogenase deficient patients in Sabah.
    Annals of tropical medicine and parasitology, 1981, Volume: 75, Issue:6

    Topics: Adolescent; Adult; Anemia, Hemolytic; Antimalarials; Child; Chloroquine; Drug Combinations; Female;

1981
The haemolytic effect of various regimens of primaquine with chloroquine in American Negroes with G6PD deficiency and the lack of an effect of various antimalarial suppressive agents on erythrocyte metabolism.
    Bulletin of the World Health Organization, 1967, Volume: 36, Issue:2

    Topics: Anemia, Hemolytic; Antimalarials; Black or African American; Chloroquine; Clinical Trials as Topic;

1967

Other Studies

19 other studies available for chloroquine and Anemia, Hemolytic

ArticleYear
Cost-Effectiveness Analysis of Sex-Stratified
    The American journal of tropical medicine and hygiene, 2020, Volume: 103, Issue:1

    Topics: Adult; Afghanistan; Aminoquinolines; Anemia, Hemolytic; Antimalarials; Chloroquine; Cost-Benefit Ana

2020
Human babesiosis in Southeast China: A case report.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2018, Volume: 68

    Topics: Administration, Intravenous; Anemia, Hemolytic; Anti-Bacterial Agents; Azithromycin; Babesiosis; C-R

2018
An in vivo drug screening model using glucose-6-phosphate dehydrogenase deficient mice to predict the hemolytic toxicity of 8-aminoquinolines.
    The American journal of tropical medicine and hygiene, 2013, Volume: 88, Issue:6

    Topics: Acute Disease; Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Disease Mode

2013
Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Oct-22, Volume: 110, Issue:43

    Topics: Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Combined Modality Therapy;

2013
AEROMEDICAL ASPECTS OF MALARIA PROPHYLAXIS WITH CHLOROQUINE-PRIMAQUINE.
    Aerospace medicine, 1963, Volume: 34

    Topics: Aerospace Medicine; Anemia; Anemia, Hemolytic; Chloroquine; Humans; Malaria; Methemoglobinemia; Moto

1963
Mode of action of antimalarial drugs.
    Ciba Foundation symposium, 1983, Volume: 94

    Topics: Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Drug Resistance; Heme; Hemin; Hemoglobins; H

1983
Chronic persistent hemolysis in an infant: can we afford to forget malaria as a cause?
    The hematology journal : the official journal of the European Haematology Association, 2002, Volume: 3, Issue:2

    Topics: Anemia, Hemolytic; Chloroquine; Chronic Disease; Humans; Infant; Infectious Disease Transmission, Ve

2002
Effect of primaquine standard dose (15 mg/day for 14 days) in the treatment of vivax malaria patients in Thailand.
    The Southeast Asian journal of tropical medicine and public health, 2001, Volume: 32, Issue:4

    Topics: Adult; Anemia, Hemolytic; Antimalarials; Chloroquine; Female; Glucosephosphate Dehydrogenase; Hemato

2001
[Perinatal transmission of Plasmodium falciparum malaria].
    Schweizerische medizinische Wochenschrift, 1975, Jun-21, Volume: 105, Issue:25

    Topics: Adult; Anemia, Hemolytic; Blood Transfusion; Chloroquine; Female; Glucosephosphate Dehydrogenase; Hu

1975
[Malaria in children, with special reference to cerebral malaria (author's transl)].
    Klinische Padiatrie, 1975, Volume: 187, Issue:5

    Topics: Age Factors; Anemia, Hemolytic; Brain Diseases; Cerebral Palsy; Child; Child, Preschool; Chloroquine

1975
Coombs'-positive hemolytic disease in malaria.
    Annals of internal medicine, 1968, Volume: 68, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Anemia, Hemolytic; Antibodies; Chloroquine; Coombs Test; Drug Erupti

1968
Babesiosis in man. Sixth documented case.
    American journal of clinical pathology, 1974, Volume: 62, Issue:5

    Topics: Anemia, Hemolytic; Animals; Babesia; Babesiosis; Bilirubin; Blood Transfusion; Chloroquine; Disease

1974
[Acute kidney failure and hemolytic anemia caused by erythrocytic G6PD dificit revealed by chloroquine administration].
    Journal d'urologie et de nephrologie, 1973, Volume: 79, Issue:9

    Topics: Acute Kidney Injury; Anemia, Hemolytic; Chloroquine; Disseminated Intravascular Coagulation; Female;

1973
Combined pyrimethamine-quinine therapy for chloroquine-resistant P. falciparum infections.
    Southern medical journal, 1969, Volume: 62, Issue:2

    Topics: Adolescent; Adult; Agranulocytosis; Anemia, Hemolytic; Chloroquine; Clinical Laboratory Techniques;

1969
Malaria in American soldiers.
    Archives of internal medicine, 1969, Volume: 123, Issue:4

    Topics: Anemia, Hemolytic; Blood Cell Count; Carrier State; Chloroquine; Hematocrit; Hemoglobinometry; Hepat

1969
Hereditary elliptocytosis associated with severe haemolytic anaemia and malaria.
    The African journal of medical sciences, 1972, Volume: 3, Issue:2

    Topics: Anemia, Hemolytic; Child, Preschool; Chloroquine; Elliptocytosis, Hereditary; Erythrocytes, Abnormal

1972
[Clinical aspects of G 6 PD deficiency in African children (apropos of 50 cases in Dakars)].
    The African journal of medical sciences, 1971, Volume: 2, Issue:2

    Topics: Adolescent; Anemia, Hemolytic; Child; Child, Preschool; Chloramphenicol; Chloroquine; Erythrocyte Co

1971
Simultaneous drug reactions in the same patient. Chloroquine-Primaquine sensitivity.
    JAMA, 1970, Apr-27, Volume: 212, Issue:4

    Topics: Adolescent; Anemia, Hemolytic; Chloroquine; Drug Hypersensitivity; Edema; Erythrocytes; Glucosephosp

1970
Hemolytic effects of standard single dosages of primaquine and chloroquine on G-6-PD-deficient caucasians.
    The Journal of laboratory and clinical medicine, 1969, Volume: 74, Issue:4

    Topics: Anemia, Hemolytic; Black or African American; Chloroquine; Chromium Isotopes; Female; Glucosephospha

1969