Page last updated: 2024-10-24

chloroquine and Androgen-Independent Prostatic Cancer

chloroquine has been researched along with Androgen-Independent Prostatic Cancer in 7 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Kudo, Y1
Endo, S1
Fujita, M1
Ota, A1
Kamatari, YO1
Tanaka, Y1
Ishikawa, T1
Ikeda, H1
Okada, T1
Toyooka, N1
Fujimoto, N1
Matsunaga, T1
Ikari, A1
Lin, JZ1
Wang, WW1
Hu, TT1
Zhu, GY1
Li, LN1
Zhang, CY1
Xu, Z1
Yu, HB1
Wu, HF1
Zhu, JG1
Lin, C1
Blessing, AM1
Pulliam, TL1
Shi, Y1
Wilkenfeld, SR1
Han, JJ1
Murray, MM1
Pham, AH1
Duong, K1
Brun, SN1
Shaw, RJ1
Ittmann, MM1
Frigo, DE1
Mortezavi, A1
Salemi, S1
Kranzbühler, B1
Gross, O1
Sulser, T1
Simon, HU1
Eberli, D1
Nguyen, HG1
Yang, JC1
Kung, HJ1
Shi, XB1
Tilki, D1
Lara, PN1
DeVere White, RW1
Gao, AC1
Evans, CP1
Babcook, MA1
Sramkoski, RM1
Fujioka, H1
Daneshgari, F1
Almasan, A1
Shukla, S1
Nanavaty, RR1
Gupta, S1
Wang, L1
Wang, J1
Xiong, H1
Wu, F1
Lan, T1
Zhang, Y1
Guo, X1
Wang, H1
Saleem, M1
Jiang, C1
Lu, J1
Deng, Y1

Other Studies

7 other studies available for chloroquine and Androgen-Independent Prostatic Cancer

ArticleYear
Discovery and Structure-Based Optimization of Novel Atg4B Inhibitors for the Treatment of Castration-Resistant Prostate Cancer.
    Journal of medicinal chemistry, 2022, 03-24, Volume: 65, Issue:6

    Topics: Apoptosis; Autophagy; Autophagy-Related Proteins; Cell Line, Tumor; Cysteine Endopeptidases; Humans;

2022
FOXM1 contributes to docetaxel resistance in castration-resistant prostate cancer by inducing AMPK/mTOR-mediated autophagy.
    Cancer letters, 2020, 01-28, Volume: 469

    Topics: AMP-Activated Protein Kinase Kinases; Apoptosis; Autophagy; Autophagy-Related Protein 7; Beclin-1; C

2020
Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling.
    Oncogene, 2021, Volume: 40, Issue:9

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Calci

2021
Inhibition of autophagy significantly increases the antitumor effect of Abiraterone in prostate cancer.
    World journal of urology, 2019, Volume: 37, Issue:2

    Topics: Abiraterone Acetate; Adenine; Antineoplastic Agents; Apoptosis; Autophagy; Autophagy-Related Protein

2019
Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model.
    Oncogene, 2014, Sep-04, Volume: 33, Issue:36

    Topics: Androgen Receptor Antagonists; Animals; Autophagy; Benzamides; Cell Line, Tumor; Chloroquine; Clomip

2014
Combination simvastatin and metformin induces G1-phase cell cycle arrest and Ripk1- and Ripk3-dependent necrosis in C4-2B osseous metastatic castration-resistant prostate cancer cells.
    Cell death & disease, 2014, Nov-20, Volume: 5

    Topics: Adaptor Proteins, Signal Transducing; Autophagy; Cell Line, Tumor; Chloroquine; Drug Combinations; G

2014
Co-targeting hexokinase 2-mediated Warburg effect and ULK1-dependent autophagy suppresses tumor growth of PTEN- and TP53-deficiency-driven castration-resistant prostate cancer.
    EBioMedicine, 2016, Volume: 7

    Topics: Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Benzamides; Cell Line, Tumor; Cell Survival

2016