chloroquine has been researched along with Alpha Virus Infections in 12 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate whether chloroquine (CQ) is more effective than meloxicam for treating early musculoskeletal pain and arthritis following acute chikungunya (CHIK) virus infection." | 9.19 | Effectiveness of chloroquine and inflammatory cytokine response in patients with early persistent musculoskeletal pain and arthritis following chikungunya virus infection. ( Chopra, A; Saluja, M; Venugopalan, A, 2014) |
| "To evaluate whether chloroquine (CQ) is more effective than meloxicam for treating early musculoskeletal pain and arthritis following acute chikungunya (CHIK) virus infection." | 5.19 | Effectiveness of chloroquine and inflammatory cytokine response in patients with early persistent musculoskeletal pain and arthritis following chikungunya virus infection. ( Chopra, A; Saluja, M; Venugopalan, A, 2014) |
| "The chloroquine treatment consisted of 600 mg at day 1, 600 mg at days 2 and 3, and 300 mg at days 4 and 5." | 2.73 | On chikungunya acute infection and chloroquine treatment. ( Boisson, V; Charrel, RN; De Lamballerie, X; Enault, S; Flahault, A; Le Grand, R; Reynier, JC; Roques, P, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rashad, AA | 1 |
| Mahalingam, S | 2 |
| Keller, PA | 1 |
| Nothias-Scaglia, LF | 1 |
| Retailleau, P | 1 |
| Paolini, J | 1 |
| Pannecouque, C | 1 |
| Neyts, J | 1 |
| Dumontet, V | 1 |
| Roussi, F | 1 |
| Leyssen, P | 1 |
| Costa, J | 1 |
| Litaudon, M | 1 |
| Chopra, A | 1 |
| Saluja, M | 1 |
| Venugopalan, A | 1 |
| Dash, PK | 1 |
| Agarwal, A | 1 |
| Sharma, S | 1 |
| Saha, A | 1 |
| Joshi, G | 1 |
| Gopalan, N | 1 |
| Sukumaran, D | 1 |
| Parida, MM | 1 |
| Ozden, S | 1 |
| Lucas-Hourani, M | 1 |
| Ceccaldi, PE | 1 |
| Basak, A | 1 |
| Valentine, M | 1 |
| Benjannet, S | 1 |
| Hamelin, J | 1 |
| Jacob, Y | 1 |
| Mamchaoui, K | 1 |
| Mouly, V | 1 |
| Desprès, P | 1 |
| Gessain, A | 1 |
| Butler-Browne, G | 1 |
| Chrétien, M | 1 |
| Tangy, F | 1 |
| Vidalain, PO | 1 |
| Seidah, NG | 1 |
| De Lamballerie, X | 2 |
| Boisson, V | 1 |
| Reynier, JC | 1 |
| Enault, S | 1 |
| Charrel, RN | 2 |
| Flahault, A | 1 |
| Roques, P | 1 |
| Le Grand, R | 1 |
| Ninove, L | 1 |
| Burt, FJ | 1 |
| Rolph, MS | 1 |
| Rulli, NE | 1 |
| Heise, MT | 1 |
| Taubitz, W | 1 |
| Cramer, JP | 1 |
| Kapaun, A | 1 |
| Pfeffer, M | 1 |
| Drosten, C | 1 |
| Dobler, G | 1 |
| Burchard, GD | 1 |
| Löscher, T | 1 |
| Savarino, A | 1 |
| Cauda, R | 1 |
| Cassone, A | 1 |
| Rao, G | 1 |
| Khan, YZ | 1 |
| Chitnis, DS | 1 |
| Boelaert, JR | 1 |
| Taramelli, D | 1 |
| Olliaro, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of the Prognostic Value of Musculoskeletal Ultrasound in Adults With Chikungunya[NCT02281123] | 200 participants (Anticipated) | Observational | 2014-07-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for chloroquine and Alpha Virus Infections
| Article | Year |
|---|---|
Antiviral treatment of chikungunya virus infection.
Topics: Alphavirus Infections; Antiviral Agents; Chikungunya virus; Chloroquine; Humans; Interferons; Ribavi | 2009 |
Chikungunya: a re-emerging virus.
Topics: Aedes; Africa; Alphavirus Infections; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, | 2012 |
2 trials available for chloroquine and Alpha Virus Infections
| Article | Year |
|---|---|
Effectiveness of chloroquine and inflammatory cytokine response in patients with early persistent musculoskeletal pain and arthritis following chikungunya virus infection.
Topics: Acute Disease; Alphavirus Infections; Arthritis; Chikungunya Fever; Chloroquine; Cytokines; Disease | 2014 |
On chikungunya acute infection and chloroquine treatment.
Topics: Alphavirus Infections; Animals; Antiviral Agents; Chikungunya virus; Chloroquine; Double-Blind Metho | 2008 |
8 other studies available for chloroquine and Alpha Virus Infections
| Article | Year |
|---|---|
Chikungunya virus: emerging targets and new opportunities for medicinal chemistry.
Topics: Alphavirus Infections; Chikungunya Fever; Chikungunya virus; Disease Outbreaks; Europe; Humans; Mode | 2014 |
Jatrophane diterpenes as inhibitors of chikungunya virus replication: structure-activity relationship and discovery of a potent lead.
Topics: Alphavirus Infections; Antiviral Agents; Chikungunya Fever; Chikungunya virus; Diterpenes; Euphorbia | 2014 |
Development of a SYBR green I-based quantitative RT-PCR for Ross River virus: Application in vector competence studies and antiviral drug evaluation.
Topics: Aedes; Alphavirus Infections; Animals; Antimalarials; Antiviral Agents; Benzothiazoles; Chlorocebus | 2016 |
Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein.
Topics: Alphavirus Infections; Amino Acid Chloromethyl Ketones; Antimalarials; Cell Line; Chikungunya virus; | 2008 |
Chikungunya fever in travelers: clinical presentation and course.
Topics: Adolescent; Adult; Alphavirus Infections; Arthralgia; Chikungunya virus; Child; Chloroquine; Female; | 2007 |
On the use of chloroquine for chikungunya.
Topics: Alphavirus Infections; Antirheumatic Agents; Arthralgia; Chikungunya virus; Chloroquine; Humans; Tre | 2007 |
Chikungunya infection in neonates.
Topics: Alphavirus Infections; Anti-Bacterial Agents; Ceftriaxone; Chikungunya virus; Chloroquine; Humans; I | 2008 |
Chloroquine enhances viral replication and murine disease.
Topics: Alphavirus Infections; Animals; Antimalarials; Cardiovirus Infections; Chloroquine; Cytokines; Encep | 2000 |