chloroquine has been researched along with Akinetic-Rigid Variant of Huntington Disease in 4 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pierzynowska, K | 1 |
| Gaffke, L | 1 |
| Hać, A | 1 |
| Mantej, J | 1 |
| Niedziałek, N | 1 |
| Brokowska, J | 1 |
| Węgrzyn, G | 1 |
| Vodicka, P | 1 |
| Lim, J | 1 |
| Williams, DT | 1 |
| Kegel, KB | 1 |
| Chase, K | 1 |
| Park, H | 1 |
| Marchionini, D | 1 |
| Wilkinson, S | 1 |
| Mead, T | 1 |
| Birch, H | 1 |
| Yates, D | 1 |
| Lyons, K | 1 |
| Dominguez, C | 1 |
| Beconi, M | 1 |
| Yue, Z | 1 |
| Aronin, N | 1 |
| DiFiglia, M | 1 |
| Glinsky, GV | 1 |
| Juopperi, TA | 1 |
| Kim, WR | 1 |
| Chiang, CH | 1 |
| Yu, H | 1 |
| Margolis, RL | 1 |
| Ross, CA | 1 |
| Ming, GL | 1 |
| Song, H | 1 |
4 other studies available for chloroquine and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Correction of Huntington's Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model.
Topics: Autophagy; Chloroquine; Drug Evaluation, Preclinical; Genes, Reporter; Genistein; HEK293 Cells; Huma | 2018 |
Assessment of chloroquine treatment for modulating autophagy flux in brain of WT and HD mice.
Topics: Animals; Antimalarials; Autophagy; Brain; Chloroquine; Disease Models, Animal; Gene Knock-In Techniq | 2014 |
SNP-guided microRNA maps (MirMaps) of 16 common human disorders identify a clinically accessible therapy reversing transcriptional aberrations of nuclear import and inflammasome pathways.
Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; alpha Karyopherins; Apoptosis | 2008 |
Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells.
Topics: Adult; Animals; Astrocytes; Cell Differentiation; Cell Line; Cell Survival; Chloroquine; Female; Hum | 2012 |