chloroquine has been researched along with Airway Remodeling in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Airway Remodeling: The structural changes in the number, mass, size and/or composition of the airway tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Current asthma therapies fail to target airway remodeling that correlates with asthma severity driving disease progression that ultimately leads to loss of lung function." | 1.51 | Autophagy Activation in Asthma Airways Remodeling. ( Deshpande, DA; Ghavami, S; Haghi, M; McAlinden, KD; Oliver, BG; Sharma, P; Sohal, SS; Xenaki, D, 2019) |
| "TAS2R agonists attenuated features of airway remodeling including smooth muscle mass, extracellular matrix deposition and pro-fibrotic signaling, and also prevented mucus accumulation and development of AHR in mice." | 1.46 | Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice. ( Deshpande, DA; Knight, MJ; Nayak, AP; Oliver, B; Pan, S; Sharma, P; Tang, F; Wang, N; Yi, R, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, P | 2 |
| Yi, R | 1 |
| Nayak, AP | 1 |
| Wang, N | 1 |
| Tang, F | 1 |
| Knight, MJ | 1 |
| Pan, S | 1 |
| Oliver, B | 1 |
| Deshpande, DA | 2 |
| McAlinden, KD | 1 |
| Ghavami, S | 1 |
| Xenaki, D | 1 |
| Sohal, SS | 1 |
| Oliver, BG | 1 |
| Haghi, M | 1 |
2 other studies available for chloroquine and Airway Remodeling
| Article | Year |
|---|---|
Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Flu | 2017 |
Autophagy Activation in Asthma Airways Remodeling.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthm | 2019 |